Role of Floating Tablet In Oral Drug Delivery System
Oral delivery of drugs is the most commonly used mode of administration among all the routes explored for the systemic delivery of drugs by numerous different dosage forms. Many components play a significant role in the development of the drug delivery system. Differences in gastric physiology such as pH and motility, have been shown to have important effects on gastric retention time and drug delivery activity in both intra- and inter-subject variability. FDDS focuses on locally active drugs with a narrow stomach absorption window or a narrow upper small intestine absorption window, are unstable in the intestinal or colonic system, and have poor solubility at high pH values.For drugs that are locally active and have a narrow absorption window in the stomach or upper small intestine and which are unstable in the intestinal or colonic setting. FDDS is particularly interesting because it has a low solubility at high pH. The methods for constructing single and multiple unit floating structures. These systems can help with a variety of issues that arise during the production of a pharmaceutical dose.
2. Dubey J, Verma N. Floating drug delivery system: A review. Int J Pharm Sci Res. 2013; 4(8):2893-99.
3. Meenakshi BN, Santosh K, Annapuram O.Floating drug delivery system: An Overview.2014; 4(2):130-34.
4. Naamani V, Jhansi C. Formulation and evaluation of floating tablets using nimesulide as a model drug. 2017;4 (9):1245-50.
5. Arunachalam, Karthikeyan M, Konam K, Prasad PH, Sethuraman S, Ashutoshkumar S, et al.Floating drug delivery systems: A review. Int J Res Pharm Sci. 2011; 2(1):76-83.
6. Chauhan YS, Kataria U, Dashora A. Formulation and evaluation of floating tablet for indomethacin. J Drug Deliv Therap. 2018;8(4):338-45.
7. Dileep R, Goudanavar P, Ramesh B. Floating drug delivery system: A review. Int J Pharm Pharm Res. 2019; 16(2):515-26.
8. Sarawade A, Ratnaparkhi MP, Chaudhari S. Floating drug delivery system: An overview. Int J Res Develop Pharm Life Sci.2014; 3(5): 1106-15.
9. Kumara SDC, Vengatesh S, Elango K, Damayanthi R, Deattu N, Christina P. Formulation and evaluation of floating tablets of ondansetron hydrochloride. Int J Drug Develop Res.2012; 4(4):265-74.
10. Pattanaya D, Mondal K, Hooain M, Das S, Ali M. A review on floating drug delivery systems in present scenario. Int J Pharm Res Health Sci. 2018; 6(5):2755-62.
11. Kaur B, Sharma S, Sharma G ,Saini R, Singh S, Nagpal M, et al. A Review of floating drug delivery system. Asian J Bio Pharm Sci. 2013; 3(24):1-6.
12. Niharika MG, Krishnamoorthy K, Akkala M. Overview on floating drug delivery system. Int J App Pharm. 2018; 10(6):65-71.
13. Meenakshi B, Santosh K, Annapurna1 O.Floating drug delivery system: A review. J Drug Deliv Therap. 2014; 4(2):130-34.
14. Neetika B, Manish G. Floating drug delivery system. Int J Pharm Res Allied Sci.2012; 1(4):20-28.
15. Niharika MG, Krishnamoorthy K, Akkala M. Overview on floating drug delivery system. Int J App Pharm. 2018; 10(6):65-71.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).