The Role of Matrix Tablet in Oral Drug Delivery System

  • Rajkumar Prasad Yadav Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India
  • F. R. Sheeba Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India
  • Mukesh Sharma Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India
  • Bhargav A Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India
  • Yaswanth Kumar Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India
  • Akshay Kumar Patel Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Abstract

Matrix tablet is an important tool for controlled and sustained release dosage forms. The important route of drug administered by oral route. The oral dosage forms developed and improvedthe patient compliance. The oral controlled release system has been developed by change to formulation scientist, due to the inability to restrain and localized of a system at target area of the gastrointestinal tract. The hydrophilic polymers are becomes product of choice for important ingredients formulation of sustained release dosage forms.The benefit of sustained release dosage forms are compared to the conventional dosage forms and uniform therapeutic effects and drug plasma concentration. The matrices used of various class of hydrophilic, hydrophobic, mineral or biodegradabletypes of polymers and their degradation product have been focused. The drug have less half-life and eliminated from the body with in short period of time. The formulation of drug matrix types have been avoided by difficult sustained release drug delivery system. The mechanism of matrix tablets include the both dissolution and diffusion controlled. It produce the therapeutic efficacy. The goal of this review article is to discuss the release mechanism of the drug dosage form of various polymers and a matrix system used in preparation of matrix tablets.


 

Keywords: Types of Matrix tablets, Mechanism of Matrix tables, Drug release

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Author Biographies

Rajkumar Prasad Yadav, Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

F. R. Sheeba, Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Mukesh Sharma, Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Bhargav A, Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Yaswanth Kumar, Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Akshay Kumar Patel, Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

Department of Pharmaceutics, Mallige College of Pharmacy, Bangalore-560090, Karnataka, India

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How to Cite
Yadav, R., Sheeba, F. R., Sharma, M., A, B., Kumar, Y., & Patel, A. (2021). The Role of Matrix Tablet in Oral Drug Delivery System. Asian Journal of Pharmaceutical Research and Development, 9(2), 80-86. https://doi.org/https://doi.org/10.22270/ajprd.v9i2.930