An Overview Onsustained Release Formulations Using Solid Dispersion as Solubility Enhancement Technique.
DOI:
https://doi.org/10.22270/ajprd.v11i3.1257Keywords:
Solid dispersion, Sustained release, Solubility, polymer, Bioavailability.Abstract
Biopharmaceutical classification system is important for determining the bioavailability of the drug. Drugs that dissolve slowly in water can be effectively solid-dispersed to increase their bioavailability. The bioavailability issue can be due to insufficient solubility of permeability. The poorly water-soluble medication dissolves more quickly when combined with the water-soluble carriers used to make solid dispersion. The review paper concentrates on the preparation techniques, benefits, drawbacks, and characterization of solid dispersion. Pharmaceuticals with sustained release have recently emerged as a very practical tool in medical practise, providing patients with a variety of real and perceived benefits. By minimising fluctuations in Using the therapeutic dose of the medicine in the body, sustained release is another promising reduction technique side effects. The major methods for creating tablets with a sustained release matrix are wet granulation, direct compression, or dispersion. In this review paper got the information about various polymers and different methods which are used for the formulate the sustained release tablet.
Downloads
Download data is not yet available.
References
1. Dharna A, Neelam S, Singh S, Aroraint S. Solid dispersions: A review on drug delivery system and solubility enhancement. J Pharm Sci Res 2017; 5(3):1-9. 2. Patil AN, Shinkar DM, Saudagar RB. Review article: solubility Enhancement by solid dispersion. Int J Curr Pharm Res 2017; 9(3):15-18.
2. Venkat B,Yadav AV. Enhancement of solubility and dissolution rate of bcs class ii pharmaceuticals by nonaquious granulation technique. International journal of pharma. research and development 2010;1 (12)
3. Patidar k. Solid Dispersion Technology: A Boon for Poor Water Soluble Drugs. Indian Journal of Novel Drug delivery 2011;2 (3):83-90
4. Kumar A., Raj V., Riyaz Md., Singh S., Review on sustained release matrix formulations, International Journal of Pharmacy and Integrated Life Sciences.2013; 1(3):1-14
5. Horter D, Dressman JB, Influence of physicochemical properties on dissolution of drug in the gastrointestinal tract, Adv Drug Del, 1997; 53: 3-14
6. Loen shargel, Andrew BC Yu. Applied Biopharmaceutics And Pharmacokinetics 2nd ed. ACC, 1985.
7. Text Book of water insoluble drug formulation by Rong Liu.Page no.500-523.
8. Anupama Kalia MP. Solid Dispersions: an approach towards enhancing dissolution rate. international Journal of Pharmacy and Pharmaceutical Sciences 2011; 3(4):9-19.
9. Bhawana Kapoor R K.Solid dispersion: an evolutionary approach for solubility enhancement of poorly water soluble drugs. International Journal of Recent Advances in Pharmaceutical Research2012; 2 (2): 1-16.
10. Asker AF, Whitworth CW.Dissolution of acetylsalicylic acid from acetylsalicylic acid-polyethylene glycol 6000 coprecipitates. Pharmazie1975; 30:530-531.
11. Mogal SA, Gurjar P N, Yamgar DS, Kamod AC. Solid dispersion technique for improving solubility of some poorly soluble drugs. Der Pharmacia Lettre 2012; 4 (5):1574 1586.
12. Singh J, Walia M, Harikumar SL, Solubility enhancement by solid dispersion method: A Review, Journal of drug delivery & therapeutics, 2013; 3(5):148-155.
13. Sekiguchi K, Obi N, Studies on Absorption of Eutectic Mixture. I. A comparison of the behaviour of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man, Chem. Pharm. Bull, 1961; 9:866-872.
14. Goldberg AH, Gibaldi M, Kanig JL, Increasing dissolutionrates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures II - experimental evaluation of a eutectic mixture: urea-acetaminophen system, J. pharm. Sci.1966; 55:482-487.
15. Castellan GW, Physical Chemistry, Addison-Wesley, Menlo Park,CA, 1983, 324-336.
16. Kumar B.Solid dispersion- A review, Pharma tutor.2017; 5(2):24-29
17. Dixit ND, Niranjan SK. “A review: Solid dispersion” World journal of pharmacy and pharmaceutical science.2014; 3(9):238-257.
18. Singh N and Sarangi MK. Solid dispersion-a novel approach for enhancement of bioavailability of poorly soluble drugs in oral drug delivery system, Global journal of pharmacy & pharmaceutical science, 2017; 3(2):001-008
19. Singh S, Baghel RS and Yadav L, “A review on solid dispersion” International journal of pharmacy & life science 2011; 2(9):1078-1095.
20. Anupama Kalia MP. Solid Dispersions: an approach towards enhancing dissolution rate. International Journal of Pharmacy and Pharmaceutical Sciences2011; 3(4):9-19.
21. Shaikh SN, Hifzurrahman S, Athar MD, Dr. Khan GJ, Raza S, Mohd AA, “Review on solid dispersion of poor water soluble drug by using natural polymers” The Pharma innovation Journal 2019; 8(1):631-636.
22. Singh S, Baghel RS and Yadav L, “A review on solid dispersion” International journal of pharmacy & life science 2011; 2(9):1078-1095
23. RenuKalyanwatSP. Solid Dispersion: a method for enhancing drug dissolution. International Journal of Drug Formulation & Research 2010; 1 (3);1-14.
24. Ladan Akbarpour Nikghalb G S. Solid Dispersion: Methods and Polymers to increase the solubility of poorly soluble drugs. Journal of Applied Pharmaceutical Science2012; 2 (10):170-175,.
25. Mogal S A GP. Solid dispersion technique for improving solubility of some poorly soluble durgs. Der Pharmacia Lettre 2012 ;4 (5):1574-1586.
26. Remington: The Science and Practice of Pharmacy, 21st ed., D. B. Troy, Ed; Baltimore,Maryland, USA: Lippincott Williams & Wilkins.
27. Tapan Kumar Giri AA. Physicochemical Classification and Formulation Development Of Solid Dispersion Of Poorly Water Soluble Drugs: An Updated Review. International Journal of Pharmaceutical & Biological Archives2010;1(4):309-324.
28. Huda N.H., Saffoon N., Sutradhar K.B., Uddin R; Enhancement of Oral Bioavailability and Solid Dispersion: A Review; Journal of Applied Pharm Sci; 2011; 1:13-20
29. Dixit AK., Singh RP; solid dispersion – A strategy for improving the solubility of poorly soluble drugs; IJRPBS; 2012; 3(2):960-966
30. Jain C.P., Sharma A; Solid dispersion: A promising technique to enhance solubility of poorly water-soluble drug; Int. J of Drug Delivery; 2011; 3:149-170.
31. Das S.K., Roy S., Kalimuthu Y., Khanam J., Nanda A; Solid Dispersions: An Approach to Enhance the Bioavailability of Poorly WaterSoluble Drugs; Int. J of Pharmacology and Pharmaceutical Technology; 1; 37 – 46
32. praveenkumar; solid dispersion – A review; Journal of pharmaceutical and scientific innovation; 2012; 1(3):27-34
33. Text book of solid dispersions as a formulation for poorly soluble compounds by G. Van den Mooter, University of Leuven, Belgium.
34. Colombo P, Bettini R, Santi P, Peppas NA; Swellable matrix for controlled drug delivery;gel-layer behaviour, mechanisms and optimal performance: Pharmaceutical science & amp, Technology Today,2000:198-204 .
35. Ravindra G, Basant K, Laxmi V, Pramod D, Shekhar V, Prasad NK, parameters Required for Sustained Release Drug Delivery systems, Indian Journal of Novel Drug Delivery, 2009:101-106.
36. Bhargava A, Rathore RPS, Tanwar YS, Gupta S, Bhaduka G, Oral Sustained Release Dosage Form: An Opportunity To Prolong The Release of Drug, IJARPB: 2013,:7-14.
37. J. Sahoo, P. N. Murthy, S. Biswal, and ManikFormulation of Sustained-Release Dosage Form of Verapamil Hydrochloride by Solid Dispersion Technique Using Eudragit RLPO or Kollidon®SRAAPS Pharm SciTech. 2009; 10(1): 27–33
38. V.D.Sundhar, M.Madhavi Latha, S.Nandha Kumar, M.D.Dhana Raju. ‘Design and evaluation of sustained release tablets containing solid dispersion of Ziprasidone hydrochloride’. Int J Pharm Tech Res. 2014; 6(3):959-968
39. Fayeza Tahseen* A.B. Gangurde, Formulation Development and In-vitro Evaluation of Sustained Release Tablets of Carvedilol Solid Dispersion Volume 3, Issue 4 (2014):52-61
40. A high bioavailability and sustained-release nano-delivery system for nintedanib based on electrospray technologyHongfei Liu,Kunyu Du Dongli Li , Yi Du , Jumei Xi , Ying Xu ,Yan Shen , Tao Jiang , Thomas J Webster Int J Nanomedicine. 2018; 10(13):8379-8393.
41. Manju.s Formulation and characterization of ibuprofen sustained release tablet by solid dispersion technique. October 2018.
42. Mr. S. Thangamuthue Enhancement of glimepiride dissolution profile by solid dispersion technique. March 2019
43. M.Sunitha Reddy, and T.Jyothirmayee. ‘Formulation and evaluation of Ibuprofen sustained release matrix tablets using Manlikara Zapota gum as a release retarding polymer’. Int J Inno Pharm Sci Res. 2015; 3(9):1350-1361.
44. S Kumar, Satish Kumar Gupta. ‘Preparation and evaluation of solid dispersions of Aceclofenac for the improvement of Dissolution rate’. J Chronother Drug Deliv. Vol 6,2015:pp.37-40.
45. Nobuyuki Tanaka ,Keiji Imai,. Development of novel sustained-release system, disintegration-controlled matrix tablet (DCMT) with solid dispersion granules of nilvadipineJ Control Release. 2005 Nov 28; 108(2-3):386-95.
46. Huyen Thi Thanh Tran 1, Jun Bom Park, Ki-Hyuk Hong, Han-Gon Choi, Hyo-Kyung Han, Jaehwi Lee, Kyung Taek Oh, Beom-Jin LeePreparation and characterization of pH-independent sustained release tablet containing solid dispersion granules of a poorly water-soluble drugInt J Pharm. 2011 Aug 30;415(1-2):83-8. 2011.05.052.
47. Sustained-release solid dispersion of pelubiprofen using the blended mixture of aminoclay and pH independent polymers: preparation and in vitro/in vivo characterization Drug Deliv. 2017; 24(1): 1731–1739.
48. panelHemlata Patil a, Roshan V. Tiwari Formulation and development of pH-independent/dependent sustained release matrix tablets of ondansetron HCl by a continuous twin-screw melt granulation process.2015; 30:33-41
49. Kosika Sandeep, ‘Formulation And Evaluation Of Sustained Release Tablets From Solid Dispersion Of Glipizide’. Int J Advan Res Found.2017; l 4:1-12.
50. Khayyam Shaikh, Formulation and evaluation of sustained release tablet from solid dispersion of lovastatin 20 January 2013
51. S. L. Neha, Neelam Singh, Mohd YasirSustained release solid dispersion of Metoclopramide HCL: formulation, evaluation and pharmacokinetic studies Journal of Applied Pharmaceutical Science 2015; 5(03):055-065.
52. Himansu Bhusan Samal, Formulation and evaluation of sustained release zidovudine matrix tablet.2011; 3(2)
53. Ruqaiyah khan, Formulation evaluation of sustained release matrix tablet of rabeprazole using wet granulation technique. J Pharm Bioallied Sci, 2014Jul-Sep; 6(3):180-184.
54. K.J Wadher, Formulation and evaluation of a sustained release tablet of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers Indian J Pharm Sci.2011; 73(2):208-215.
55. Rita B and Suresh V, Formulation and evaluation of Sustained release matrix tablet of nifedipine. ISSN 2386-5180 Vol. 3 No.1:7
56. K.R. Shankar, Formulation and evaluation of sustained release matrix tablets of baclofen IJPSR 2018:4402-09
57. 57. Priyadharshini, *Akelesh Formulation and evaluation sustained release matrix tablet using atenol hydrochloride wjpmr, 2018; 4(12):297-306
58. Muhammad SAMIE Design, Formulation and In Vitro Evaluation of Sustained-release Tablet Formulations of Levosulpiride Turk J Pharm Sci 2018;15(3):309-318
59. Basavaraja Formulation and Evaluation of Sustained Release Matrix Tablets of Flurbiprofen by Using Natural and Synthetic Polymers Basavaraja et al /J. Pharm. Sci. & Res. 2015; 7(6):274-281
60. V. Kamalakkannan. Design and Development of Sustained Release Matrix Tablets of Tramadol Hydrochloride are using Gum kondagogu as a Natural polymer Sch. Acad. J. Pharm., 2015; 4(3):199-207
61. A. Bharathi ,Formulation development and evaluation of sustained release matrix tablets of quetiapine fumarate .Journal of Chemical and Pharmaceutical Research, 2014; 6(4):628-632
62. Nisha Singh, Formulation and Evaluation of Sustained Release Matrix Tablets of Captopril .Singh et al., 2020; 11(11):7071-7078,
63. Gaurav Agarwal, Shilpi Agarwal Formulation & Evaluation of Sustained Release Matrix Tablet of Repaglinide. ISSN 2578-0247 2018:23.
64. Indranil Kumar Yadav ,Formulation, evaluation and optimization of aceclofenac sustained release matrix tablet CODEN (USA): IJPRIF 2010; 2(1):592-598,
65. Upendra Nagaich, Charu Bhart , Diclofenac Sodium Loaded Sustained Release Matrix Tablet Possessing Natural and Synthetic Polymers: Formulation and in vitro Characterization 2014
66. C.H.V. Alekhya , A research article on formulation and evaluation of sustained release matrix tablet of oxprenolol hydrochloride International Journal of Research in Pharmaceutical and Nano Sciences. 2015; 4(5):290-297.
67. Navin Dixit, Sheo Dutt Maurya, Bhanu P.S.Sagar. Sustained Release Drug Delivery System. Ind J Res Pharm Biotech. 20131; (3):305-310.
2. Venkat B,Yadav AV. Enhancement of solubility and dissolution rate of bcs class ii pharmaceuticals by nonaquious granulation technique. International journal of pharma. research and development 2010;1 (12)
3. Patidar k. Solid Dispersion Technology: A Boon for Poor Water Soluble Drugs. Indian Journal of Novel Drug delivery 2011;2 (3):83-90
4. Kumar A., Raj V., Riyaz Md., Singh S., Review on sustained release matrix formulations, International Journal of Pharmacy and Integrated Life Sciences.2013; 1(3):1-14
5. Horter D, Dressman JB, Influence of physicochemical properties on dissolution of drug in the gastrointestinal tract, Adv Drug Del, 1997; 53: 3-14
6. Loen shargel, Andrew BC Yu. Applied Biopharmaceutics And Pharmacokinetics 2nd ed. ACC, 1985.
7. Text Book of water insoluble drug formulation by Rong Liu.Page no.500-523.
8. Anupama Kalia MP. Solid Dispersions: an approach towards enhancing dissolution rate. international Journal of Pharmacy and Pharmaceutical Sciences 2011; 3(4):9-19.
9. Bhawana Kapoor R K.Solid dispersion: an evolutionary approach for solubility enhancement of poorly water soluble drugs. International Journal of Recent Advances in Pharmaceutical Research2012; 2 (2): 1-16.
10. Asker AF, Whitworth CW.Dissolution of acetylsalicylic acid from acetylsalicylic acid-polyethylene glycol 6000 coprecipitates. Pharmazie1975; 30:530-531.
11. Mogal SA, Gurjar P N, Yamgar DS, Kamod AC. Solid dispersion technique for improving solubility of some poorly soluble drugs. Der Pharmacia Lettre 2012; 4 (5):1574 1586.
12. Singh J, Walia M, Harikumar SL, Solubility enhancement by solid dispersion method: A Review, Journal of drug delivery & therapeutics, 2013; 3(5):148-155.
13. Sekiguchi K, Obi N, Studies on Absorption of Eutectic Mixture. I. A comparison of the behaviour of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man, Chem. Pharm. Bull, 1961; 9:866-872.
14. Goldberg AH, Gibaldi M, Kanig JL, Increasing dissolutionrates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures II - experimental evaluation of a eutectic mixture: urea-acetaminophen system, J. pharm. Sci.1966; 55:482-487.
15. Castellan GW, Physical Chemistry, Addison-Wesley, Menlo Park,CA, 1983, 324-336.
16. Kumar B.Solid dispersion- A review, Pharma tutor.2017; 5(2):24-29
17. Dixit ND, Niranjan SK. “A review: Solid dispersion” World journal of pharmacy and pharmaceutical science.2014; 3(9):238-257.
18. Singh N and Sarangi MK. Solid dispersion-a novel approach for enhancement of bioavailability of poorly soluble drugs in oral drug delivery system, Global journal of pharmacy & pharmaceutical science, 2017; 3(2):001-008
19. Singh S, Baghel RS and Yadav L, “A review on solid dispersion” International journal of pharmacy & life science 2011; 2(9):1078-1095.
20. Anupama Kalia MP. Solid Dispersions: an approach towards enhancing dissolution rate. International Journal of Pharmacy and Pharmaceutical Sciences2011; 3(4):9-19.
21. Shaikh SN, Hifzurrahman S, Athar MD, Dr. Khan GJ, Raza S, Mohd AA, “Review on solid dispersion of poor water soluble drug by using natural polymers” The Pharma innovation Journal 2019; 8(1):631-636.
22. Singh S, Baghel RS and Yadav L, “A review on solid dispersion” International journal of pharmacy & life science 2011; 2(9):1078-1095
23. RenuKalyanwatSP. Solid Dispersion: a method for enhancing drug dissolution. International Journal of Drug Formulation & Research 2010; 1 (3);1-14.
24. Ladan Akbarpour Nikghalb G S. Solid Dispersion: Methods and Polymers to increase the solubility of poorly soluble drugs. Journal of Applied Pharmaceutical Science2012; 2 (10):170-175,.
25. Mogal S A GP. Solid dispersion technique for improving solubility of some poorly soluble durgs. Der Pharmacia Lettre 2012 ;4 (5):1574-1586.
26. Remington: The Science and Practice of Pharmacy, 21st ed., D. B. Troy, Ed; Baltimore,Maryland, USA: Lippincott Williams & Wilkins.
27. Tapan Kumar Giri AA. Physicochemical Classification and Formulation Development Of Solid Dispersion Of Poorly Water Soluble Drugs: An Updated Review. International Journal of Pharmaceutical & Biological Archives2010;1(4):309-324.
28. Huda N.H., Saffoon N., Sutradhar K.B., Uddin R; Enhancement of Oral Bioavailability and Solid Dispersion: A Review; Journal of Applied Pharm Sci; 2011; 1:13-20
29. Dixit AK., Singh RP; solid dispersion – A strategy for improving the solubility of poorly soluble drugs; IJRPBS; 2012; 3(2):960-966
30. Jain C.P., Sharma A; Solid dispersion: A promising technique to enhance solubility of poorly water-soluble drug; Int. J of Drug Delivery; 2011; 3:149-170.
31. Das S.K., Roy S., Kalimuthu Y., Khanam J., Nanda A; Solid Dispersions: An Approach to Enhance the Bioavailability of Poorly WaterSoluble Drugs; Int. J of Pharmacology and Pharmaceutical Technology; 1; 37 – 46
32. praveenkumar; solid dispersion – A review; Journal of pharmaceutical and scientific innovation; 2012; 1(3):27-34
33. Text book of solid dispersions as a formulation for poorly soluble compounds by G. Van den Mooter, University of Leuven, Belgium.
34. Colombo P, Bettini R, Santi P, Peppas NA; Swellable matrix for controlled drug delivery;gel-layer behaviour, mechanisms and optimal performance: Pharmaceutical science & amp, Technology Today,2000:198-204 .
35. Ravindra G, Basant K, Laxmi V, Pramod D, Shekhar V, Prasad NK, parameters Required for Sustained Release Drug Delivery systems, Indian Journal of Novel Drug Delivery, 2009:101-106.
36. Bhargava A, Rathore RPS, Tanwar YS, Gupta S, Bhaduka G, Oral Sustained Release Dosage Form: An Opportunity To Prolong The Release of Drug, IJARPB: 2013,:7-14.
37. J. Sahoo, P. N. Murthy, S. Biswal, and ManikFormulation of Sustained-Release Dosage Form of Verapamil Hydrochloride by Solid Dispersion Technique Using Eudragit RLPO or Kollidon®SRAAPS Pharm SciTech. 2009; 10(1): 27–33
38. V.D.Sundhar, M.Madhavi Latha, S.Nandha Kumar, M.D.Dhana Raju. ‘Design and evaluation of sustained release tablets containing solid dispersion of Ziprasidone hydrochloride’. Int J Pharm Tech Res. 2014; 6(3):959-968
39. Fayeza Tahseen* A.B. Gangurde, Formulation Development and In-vitro Evaluation of Sustained Release Tablets of Carvedilol Solid Dispersion Volume 3, Issue 4 (2014):52-61
40. A high bioavailability and sustained-release nano-delivery system for nintedanib based on electrospray technologyHongfei Liu,Kunyu Du Dongli Li , Yi Du , Jumei Xi , Ying Xu ,Yan Shen , Tao Jiang , Thomas J Webster Int J Nanomedicine. 2018; 10(13):8379-8393.
41. Manju.s Formulation and characterization of ibuprofen sustained release tablet by solid dispersion technique. October 2018.
42. Mr. S. Thangamuthue Enhancement of glimepiride dissolution profile by solid dispersion technique. March 2019
43. M.Sunitha Reddy, and T.Jyothirmayee. ‘Formulation and evaluation of Ibuprofen sustained release matrix tablets using Manlikara Zapota gum as a release retarding polymer’. Int J Inno Pharm Sci Res. 2015; 3(9):1350-1361.
44. S Kumar, Satish Kumar Gupta. ‘Preparation and evaluation of solid dispersions of Aceclofenac for the improvement of Dissolution rate’. J Chronother Drug Deliv. Vol 6,2015:pp.37-40.
45. Nobuyuki Tanaka ,Keiji Imai,. Development of novel sustained-release system, disintegration-controlled matrix tablet (DCMT) with solid dispersion granules of nilvadipineJ Control Release. 2005 Nov 28; 108(2-3):386-95.
46. Huyen Thi Thanh Tran 1, Jun Bom Park, Ki-Hyuk Hong, Han-Gon Choi, Hyo-Kyung Han, Jaehwi Lee, Kyung Taek Oh, Beom-Jin LeePreparation and characterization of pH-independent sustained release tablet containing solid dispersion granules of a poorly water-soluble drugInt J Pharm. 2011 Aug 30;415(1-2):83-8. 2011.05.052.
47. Sustained-release solid dispersion of pelubiprofen using the blended mixture of aminoclay and pH independent polymers: preparation and in vitro/in vivo characterization Drug Deliv. 2017; 24(1): 1731–1739.
48. panelHemlata Patil a, Roshan V. Tiwari Formulation and development of pH-independent/dependent sustained release matrix tablets of ondansetron HCl by a continuous twin-screw melt granulation process.2015; 30:33-41
49. Kosika Sandeep, ‘Formulation And Evaluation Of Sustained Release Tablets From Solid Dispersion Of Glipizide’. Int J Advan Res Found.2017; l 4:1-12.
50. Khayyam Shaikh, Formulation and evaluation of sustained release tablet from solid dispersion of lovastatin 20 January 2013
51. S. L. Neha, Neelam Singh, Mohd YasirSustained release solid dispersion of Metoclopramide HCL: formulation, evaluation and pharmacokinetic studies Journal of Applied Pharmaceutical Science 2015; 5(03):055-065.
52. Himansu Bhusan Samal, Formulation and evaluation of sustained release zidovudine matrix tablet.2011; 3(2)
53. Ruqaiyah khan, Formulation evaluation of sustained release matrix tablet of rabeprazole using wet granulation technique. J Pharm Bioallied Sci, 2014Jul-Sep; 6(3):180-184.
54. K.J Wadher, Formulation and evaluation of a sustained release tablet of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers Indian J Pharm Sci.2011; 73(2):208-215.
55. Rita B and Suresh V, Formulation and evaluation of Sustained release matrix tablet of nifedipine. ISSN 2386-5180 Vol. 3 No.1:7
56. K.R. Shankar, Formulation and evaluation of sustained release matrix tablets of baclofen IJPSR 2018:4402-09
57. 57. Priyadharshini, *Akelesh Formulation and evaluation sustained release matrix tablet using atenol hydrochloride wjpmr, 2018; 4(12):297-306
58. Muhammad SAMIE Design, Formulation and In Vitro Evaluation of Sustained-release Tablet Formulations of Levosulpiride Turk J Pharm Sci 2018;15(3):309-318
59. Basavaraja Formulation and Evaluation of Sustained Release Matrix Tablets of Flurbiprofen by Using Natural and Synthetic Polymers Basavaraja et al /J. Pharm. Sci. & Res. 2015; 7(6):274-281
60. V. Kamalakkannan. Design and Development of Sustained Release Matrix Tablets of Tramadol Hydrochloride are using Gum kondagogu as a Natural polymer Sch. Acad. J. Pharm., 2015; 4(3):199-207
61. A. Bharathi ,Formulation development and evaluation of sustained release matrix tablets of quetiapine fumarate .Journal of Chemical and Pharmaceutical Research, 2014; 6(4):628-632
62. Nisha Singh, Formulation and Evaluation of Sustained Release Matrix Tablets of Captopril .Singh et al., 2020; 11(11):7071-7078,
63. Gaurav Agarwal, Shilpi Agarwal Formulation & Evaluation of Sustained Release Matrix Tablet of Repaglinide. ISSN 2578-0247 2018:23.
64. Indranil Kumar Yadav ,Formulation, evaluation and optimization of aceclofenac sustained release matrix tablet CODEN (USA): IJPRIF 2010; 2(1):592-598,
65. Upendra Nagaich, Charu Bhart , Diclofenac Sodium Loaded Sustained Release Matrix Tablet Possessing Natural and Synthetic Polymers: Formulation and in vitro Characterization 2014
66. C.H.V. Alekhya , A research article on formulation and evaluation of sustained release matrix tablet of oxprenolol hydrochloride International Journal of Research in Pharmaceutical and Nano Sciences. 2015; 4(5):290-297.
67. Navin Dixit, Sheo Dutt Maurya, Bhanu P.S.Sagar. Sustained Release Drug Delivery System. Ind J Res Pharm Biotech. 20131; (3):305-310.
Published
2023-06-15
How to Cite
Nikita, B., Atish, V., Vivek Kumar, R., Poonam, R., & Joshi, V. (2023). An Overview Onsustained Release Formulations Using Solid Dispersion as Solubility Enhancement Technique. Asian Journal of Pharmaceutical Research and Development, 11(3), 84–91. https://doi.org/10.22270/ajprd.v11i3.1257
Issue
Section
Review Articles
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.