Nanoemulsion as Novel Drug Delivery System: Development, Characterization and Application

  • Nikhil Dhumal Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur, Satara 415004, Maharashtra.
  • Vishal Yadav Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur, Satara 415004, Maharashtra.
  • Smita Borkar Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur, Satara 415004, Maharashtra.

Abstract

A dispersed nano-system with droplet sizes as small as submicrons is called a nanoemulsion. Nanoemulsions are thermodynamically stable, transparent, isotropic liquid mixtures of oil, water, surfactant, and co-surfactant. Nanoemulsion typically has droplet sizes between 20 and 200 nanometer. The size and composition of the scattered particles in a continuous phase are the primary distinctions between an emulsion and a nanoemulsion. This approach is intended to alleviate some of the issues that low bioavailability and noncompliance, two issues with traditional drug delivery systems, bring up.Today, nano emulsion can be created for a number of administration routes. A nano emulsion formulation can be considered an effective, secure, and patient-compliant pharmaceutical delivery method. Nowadays, nano emulsions have attracted a lot of interest in pharmacotherapy, dosage form design, and research. A surfactant and a cosurfactant can preserves the stability components of nanoemulsion. Brief details on the types, preparation process, stability, assessment, and applications of nanoemulsion are provided in this review.


 

Keywords: Nanoemulsion, emulsifier, Microfluidization, sonotrode, cosurfactant.

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Author Biographies

Nikhil Dhumal, Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur, Satara 415004, Maharashtra.

Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur,  Satara 415004, Maharashtra.

Vishal Yadav, Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur, Satara 415004, Maharashtra.

Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur,  Satara 415004, Maharashtra.

Smita Borkar, Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur, Satara 415004, Maharashtra.

Department of Pharmaceutics, Arvind Gavali College of Pharmacy Jaitapur,  Satara 415004, Maharashtra.

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How to Cite
Dhumal, N., Yadav, V., & Borkar, S. (2022). Nanoemulsion as Novel Drug Delivery System: Development, Characterization and Application. Asian Journal of Pharmaceutical Research and Development, 10(6), 120-127. https://doi.org/https://doi.org/10.22270/ajprd.v10i6.1205