Studi Antiviral Andrographis Paniculata, For Herpes Simplex Virustipe 1 (HSV-1) Treatment: In Slico Study
Herpes simplex virus type 1 (HSV-1) is a lifelong infectious disease. Research and drug development for this disease continues to be developed. Andrographis paniculata or commonly known as Sambiloto is a plant that is commonly used empirically as an HSV-1 drug. Further research is needed to determine the effectiveness of these plants as candidates for HSV-1 treatment. This study will determine several bioactive compounds contained in Sambiloto against the HSV-1 receptor in an insilico study which can be the basis for the discovery of new drugs in the treatment of HSV-1 infection.
2. Pongmuangmul S, Phumiamorn S, Sanguansermsri P, Wongkattiya N, Fraser IH, Sanguansermsri D. Anti-herpes simplex virus activities of monogalactosyl diglyceride and digalactosyl diglyceride from Clinacanthus nutans, a traditional Thai herbal medicine. Asian Pac J Trop Biomed. 2016;6(3):192-197. doi:10.1016/j.apjtb.2015.12.014
3. Tajidin NE, Shaari K, Maulidiani M, Salleh NS, Ketaren BR, Mohamad M. Metabolite profiling of Andrographis paniculata (Burm. f.) Nees. young and mature leaves at different harvest ages using 1H NMR-based metabolomics approach. Sci Rep. 2019;9(1):1-10. doi:10.1038/s41598-019-52905-z
4. Chao WW, Lin BF. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010;5:1-15. doi:10.1186/1749-8546-5-17
7. Weni M, Safithri M, Seno DSH. Molecular Docking of Active Compounds Piper crocatum on the A-Glucosidase Enzyme as Antidiabetic. Indones J Pharm Sci Technol. 2020;7(2):64. doi:10.24198/ijpst.v7i2.21120
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