Estimation the Presence of Heavy Metals and Trace Elements in Indian Herbal Cosmetics by Atomic Absorption Spectrophotometer

Authors

  • Krishnasis Chakraborty Department of Quality Assurance Al-Ameen College of Pharmacy, Opposite to Lalbagh Main Gate, Hosur road, Bangalore, India
  • Suraj Chaudhary Department of Quality Assurance Al-Ameen College of Pharmacy, Opposite to Lalbagh Main Gate, Hosur road, Bangalore, India

DOI:

https://doi.org/10.22270/ajprd.v7i5.556

Keywords:

Herbal Cosmetics, WHO, GMP, AAS, Trace elements, Heavy Metals.

Abstract

Heavy metals are identically Pb, Cd and micronutrients elements like Ca, Mg, Al, Cu and Zn were quantitatively estimated using Flame Atomic Absorption Spectrometry (FAAS). Similarly, heavy metals such as As and Hg were quantitatively estimated by Hydride Generation Technique i.e. Cold Vapor Atomic Absorption Spectrometry method expending nitrogen as carrier gas in 30 herbal cosmetic preparations available in Indian markets. The results designate that among the toxic heavy metals. In the present study, Arsenic was found significantly well below the permissible limit, but Cd was found above the permissible limit in the all samples. Trace elements like Ca and Mg were found in higher amount than compare to Al, Cu, and Zn. Presence of trace elements can corroborate to be beneficial but existence of toxic heavy metals in such amounts certainly has adverse effects on the consumer health who always take the herbal products in an impression of being safe because of the natural origin. In conclusion, execution of strict and isolated regulatory guidelines and promotion of Good Analytical Practice (GAP), Good Manufacturing Practices (GMP) and Good Agricultural and Control Practices (GACP) is suggested for herbal cosmetics by WHO and other regulatory agencies. This study presents the status of heavy metals and trace elements in marketed herbal cosmetic formulations and provides a simple and convenient AAS method which can effectively be adopted at Industrial level for the quality control and standardization of herbal cosmetic preparations and other related products.

 

Downloads

Download data is not yet available.

Author Biographies

Krishnasis Chakraborty, Department of Quality Assurance Al-Ameen College of Pharmacy, Opposite to Lalbagh Main Gate, Hosur road, Bangalore, India

Department of Quality Assurance Al-Ameen College of Pharmacy, Opposite to Lalbagh Main Gate, Hosur road, Bangalore, India

Suraj Chaudhary, Department of Quality Assurance Al-Ameen College of Pharmacy, Opposite to Lalbagh Main Gate, Hosur road, Bangalore, India

Department of Quality Assurance Al-Ameen College of Pharmacy, Opposite to Lalbagh Main Gate, Hosur road, Bangalore, India

References

1. Kapoor V.P. Herbal cosmetic for skin and hair care, Nat. Prod. Radiance. 2005;4(4):306-12
2. Goodman and Gillman, “Pharmacological Basis of Therapeutics”, 6th Ed., 321
3. WHO. Environmental Health Criteria: International Programme on Chemical Safety. World Health Organization, Geneva.1995:165
4. Ernst E. Toxic heavy metals and undeclared drugs in Asian herbal medicines, Trends Pharmacol. Sc.
2002; 23:136-9
3. Sun H.W., Ying. G., Yuan. C.G., Zhang. Y.X., LiIi. Y. and De-q. Z. Determination of trace lead in Chinese herbs by derivative flame atomic absorption spectrometry using an atom trapping technique. Anal. Sci. 2002; 18:325-28
4. Ayenimo J.G., Yusuf A.M., Adekunle A.S. and Makinde O.W. Heavy Metal Exposure from Personal Care Products, Bull. Environ. Contam. Toxicol.2010; 84:8-14
5. Sukender K., Jaspreet S., Sneha D. and Munish G AAS Estimation of Heavy metals and Trace Elements in Indian Herbal Cosmetic preparation. Res. J. Sci. 2012;2(3): 46-51
6. Health Canada, Draft guidance on heavy metal impurities in cosmetics, Section 4
7. Ajayi S.O., Oladipo M.O.A., Ogunsuyi H.O. and Adebayo A.O., Determination of the minor and trace elements in Biriniwa tin pyrite and ornamental lead/zinc ore using neutron activation analysis, Bull. Chem Soc. Ethiopia. 2002; 16(2):207-11
8. Nanorom I.C., Igwe T.C. and Oji-Nnorom C.G., Trace metal contents of facial (make-up) cosmetics commonly used in Nigeria, Afr. J. Biotechnol. 2005;4(10):1133-8
9. Nwoko C.O. and Mgbeahuruike L., Heavy metal contamination of ready-to-use herbal remedies in south eastern Nigeria, Pak. J. Nutr., 2011;10(10):959-64
10. Al-Omari S., Determination of essential and toxic trace elements in ten herbal medicines using energy-dispersive XRF analysis, X-Ray Spectrom. 2011; 40:31–6
11. Gomez M.R., Cerutti S., Somb L.L., Silva M.F. and Martınez L.D., Determination of heavy metals for the quality control in Argentinian herbal medicines by ETAAS and ICP-OES, Food and Chem. Toxicol. 2007; 45:1060-4
12. Ajasa A.M.O., Bellob M.O., Ibrahimb A.O., Ogunwandea I.A. and Olaworeb N.O., Heavy trace metals and macronutrients status in herbal plants of Nigeria, Food Chemistry. 2004; 85(1):67-71
13. Sharma D.K., Rai S., Arora S.S., Gupta P.M., Sharma R. and Chopra A.K. Study of the trace elements in Aloe veraL. (Aloe barbandensisMiller) viz. Liliaceae and its biological and environmental importance, J. Chem. Pharm. Res., 2011; 3(3):64
14. Farr G., The hair tissue mineral analysis/why heavy metals are a hazard to your health, Updated 31Dec. 2009.
15. Naithani V., Pathak N. and Chaudhary M. Evaluation of heavy metals in two major ingredients of Ampucare, Int. J. Pharm. Sc. Drug Res.,2010; 2(2):137-44
16. Baranowska, I., Srogi, K., Wlochowicz, A. Szczepanik, K. Determination of Heavy Metal contents in samples of Medi-cinal Herbs. Polish Journal of Environmental Studies, 2002;11(5):467-71
17. Barr. R. D., Woodger B.M. and Rees. P.H. Levels of mercury in urine correlated with the use of skin lightening creams. Am. J. Clin. Pathol.1973;59: 36-40
18. Noviana, E., D.P. Heri, Astuti, and A. Rohman. Validation of mercury analyzer for determination of mercury in snake fruit. Int. Food Res. J.2012; 19(3): 933-36
19. World Health Organization (2003). Traditional Medicine, Fact sheet No. 134 Vogel A.I. A text book of quantitative inorganic chemical analysis including elementary instrumental analysis. Logman Inc., London. 2001; 5th edition: 80

Published

2019-10-15

How to Cite

Chakraborty, K., & Chaudhary, S. (2019). Estimation the Presence of Heavy Metals and Trace Elements in Indian Herbal Cosmetics by Atomic Absorption Spectrophotometer. Asian Journal of Pharmaceutical Research and Development, 7(5), 59–64. https://doi.org/10.22270/ajprd.v7i5.556