FORMULATION AND EVALUATION OF ORMELOXIFENE FAST DISSOLVING TABLETS

Authors

  • Abdul Hasan Sathali Department of Pharmaceutics, College of Pharmacy, Madurai Medical College, Madurai- 625 020, Tamil Nadu, India
  • Ramanathan M Department of Pharmaceutics, College of Pharmacy, Madurai Medical College, Madurai- 625 020, Tamil Nadu, India.

DOI:

https://doi.org/10.22270/ajprd.v6i3.373

Keywords:

Ormeloxifene, superdisintegrants, kneading, dissolution, disintegration time and solid dispersion

Abstract

The objective of the present work was to enhancedissolution and solubility of slightly water soluble ormeloxifene hydrochloride and formulate fast dissolving tablets. The research work was two-phase process, the first phase was to enhance the solubility and dissolution of ormeloxifene. For this object drugwas processed with different solid dispersion techniques like kneading, co precipitation, melting and solvent evaporation technique with

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References

1. Chaudhary V.B and Pate J.K., “Cyclodextrin inclusion complex to enhance solubility of Bhpoorly water soluble drugs”, ijpsr, 2013; vol. 4(1): 68-76.
2. DebjitBhowmik, Chiranjib.B, Krishnakanth, Pankaj, R.MargretChandira, “Fast dissolving tablet: an overview”, Journal of chemical and pharmaceutical research, 2009, 163-177.
3. Abd Al Hammid, Shaimaa N and Ehsan Ali Mohamed, “Formulation and evaluation of Rosuvastation orodispersible tablets”. IJPPS,2013, volume 5
4. Hyma .P, Ravikanth.N, and Pradeep Reddy C.H, “Improvement of solubility and dissolution rate of Pioglitazone by solid dispersions technique”, International journal of advances in pharmaceutical sciences, 2012, volume 3issue 6pages 423-431.
5. Abdul HasanSathali A and Selvaraj V., “Enhancement of solubility and dissolution rate of Racecadotril by solid dispersion methods”, Jur.Curr. Chem. Pharm. Sc.2012, 2(3), 209-225
6. Prabhakar Shires, SreenivasaRao.K and Mohamed Majid Iqbal, “Formulation and evaluation of cyclodextrin inclusion complex tablets of water insoluble drug-Glimipiride”, International journal of research in pharmacy and chemistry, 2012.
7. Deepthimathew, “A study on suitability of Nimesulide-betacyclodextrin complex in oral and topical dosage forms”, International journal of pharmacy and pharmaceutical sciences, 2009, vol. 1, suppl 1.
8. Abhilash M, Prasanth VV, and Shanth Kumar, Formulation and evaluation of solid dispersion of melitracen, IJPC, vol 2(3), 2013.
9. Nagesh C,Nagendra Rao R, Rengaraju D and Vengadesh JS, Solubility and dissolution enhancement of cefixime using natural polymer by solid dispersion technique, IJRPC,2011, page 283-287.
10. Imran Shekh, Vishal Gupta, Abhay Jain and Naveen Gupta, “Preparation and characterisation of beta cyclodextrin Aspirin Inclusion complex”, International journal of pharmacy & life sciences,2011.
11. Sawarikar P.P, Sridhar B K, and Shivkumar S, “Formulation and evaluation of fast dissolving / disintegrating tablets of Isoxsuprine hydrochloride”, Journal of current pharmaceutical research, 2010, 3(1): 41-46
12. AmitModi, Vandana Singh, Arun Gupta, AshlshAgrawal , “Formulation and evaluation of Fast dissolving tablets of Diclofenac sodium using different superdisintigrants by direct compression method”, International journal of pharmaceutical & biological archives,2012, 3(4):1003-1007.
13. Indian pharmacopeia, 2010
14. Ashish P,Harsoliya M S, Pathan J K, and Shruti S, A review formulation of mouth dissolving tablets, Int. jur.of pharmaceutical and clinical science, 2011.
15. Manish R, Sandip B, Gautam D and Mukesh, Formulation and evaluation of intraorally fast dissolving tablet of olmesartan medoxomil, Scholars research library, 2013, vol 5(1): page 232-237.
16. ShuklaVikesh, MasareddyRajashree, Anghore Ashok, ManviFakkirappa.V, “Influence of ß-cyclodextrincomplexation on ketoprofen release from matrix formulation”, International journal of pharmaceutical sciences and drug research, 2009 1(3): 195-202.

Published

2018-07-10

How to Cite

Sathali, A. H., & M, R. (2018). FORMULATION AND EVALUATION OF ORMELOXIFENE FAST DISSOLVING TABLETS. Asian Journal of Pharmaceutical Research and Development, 6(3), 17–31. https://doi.org/10.22270/ajprd.v6i3.373

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