Pelletalization Techniques: A Review
Keywords:
Pelletization, extrusion, spheronization, cryopelletizationAbstract
In present times, the pelletization technologies are giving much attention as they represent an efficient pathway for manufacture of new drug delivery system .It has good advantage over the conventional dosage form. Pelletization technique help in the formation of spherical beads or pellets having a diameter 0.5 -1.5 mm which can be eventually coated for preparation of modified release dosage form .It leads to an improvement in flow ability, appearance and mixing properties thus avoiding for generation of excessive dust and reduces segregation and remove the undesirable properties and improve the physical and chemical properties of fine powder. The aim of this study is to provide detailed and different techniques of pelletization such as powder layering, suspension /solution layering, extrusion and spheronization, cryopelletization, etc. It also gives a brief idea about the evaluation of pellets and application of pelletization technique.
Downloads
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).