A Comprehensive Review on the Phytochemistry, Traditional Uses and Pharmacological Activities of Aegle Marmelos: Current Evidence and Future Perspectives

Authors

  • Shruti Raval Department of Pharmacology, A-One Pharmacy College, SNME campus, Naroda -Dehgam road, Enasan, Ahmedabad-382430, Gujarat, India.
  • Dr. Dhaval Patel Department of Pharmacology, A-One Pharmacy College, SNME campus, Naroda -Dehgam road, Enasan, Ahmedabad-382430, Gujarat, India.
  • Dr. Pankti Dalmati Department of Pharmacology, A-One Pharmacy College, SNME campus, Naroda -Dehgam road, Enasan, Ahmedabad-382430, Gujarat, India.
  • Payal Prasad Department of Pharmacology, A-One Pharmacy College, SNME campus, Naroda -Dehgam road, Enasan, Ahmedabad-382430, Gujarat, India.
  • Ritu chandel Department of Pharmacology, A-One Pharmacy College, SNME campus, Naroda -Dehgam road, Enasan, Ahmedabad-382430, Gujarat, India.

DOI:

https://doi.org/10.22270/ajprd.v14i5.1869

Abstract

Aegle marmelos (L.) Correa (Rutaceae), commonly known as bael, is a medicinally important tree widely distributed across the Indian subcontinent and Southeast Asia. Almost every plant part has been used in Ayurvedic, Siddha and Unani medicine. This review systematically examines the botanical profile, ethnomedicinal uses, phytochemical composition and experimental pharmacological evidence for A. marmelos. Major bioactive classes include alkaloids (aegeline, skimmianine), coumarins (marmelosin, imperatorin, marmin, and marmesin), flavonoids (rutin, quercetin), phenolic acids and terpenoids. Preclinical studies demonstrate antidiabetic, antioxidant, antidiarrhoeal, anti-inflammatory, hepatoprotective, antidepressant, and antihyperlipidaemic, antimicrobial and antifungal activities. Mechanistic insights implicate inhibition of carbohydrate-digesting enzymes, enhancement of endogenous antioxidant defences, modulation of inflammatory pathways and monoaminergic neurotransmission. Despite robust preclinical data, high-quality clinical trials and standardised phytopharmaceutical development remain limited. This review synthesises current evidence, identifies research gaps and outlines future directions for the translational development of A. marmelos-based therapeutics.

 

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References

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Published

2026-10-15

How to Cite

Shruti Raval, Dr. Dhaval Patel, Dr. Pankti Dalmati, Payal Prasad, & Ritu chandel. (2026). A Comprehensive Review on the Phytochemistry, Traditional Uses and Pharmacological Activities of Aegle Marmelos: Current Evidence and Future Perspectives. Asian Journal of Pharmaceutical Research and Development, 14(5), 55–59. https://doi.org/10.22270/ajprd.v14i5.1869

Issue

Vol. 14 No. 5 (2026): Volume 14 Issue 5 Sept - Oct. 2026

Section

Review Articles

Copyright (c) 2026 Shruti Raval, Dr. Dhaval Patel, Dr. Pankti Dalmati, Payal Prasad, Ritu chandel

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