An Antihyperlipidemic Agents Review for Atherosclerosis Treatment

Authors

  • Rutuja Talekar Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India
  • Nanasaheb Gorade Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India
  • Sachin Jadhav Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India
  • Pratiksha Chormage Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India
  • Shivani Gadekar Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India
  • Swati H.Tarkase Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India
  • Dr.Gajanan Sanap Department of Medicinal Chemistry, Late Bhagirathi Yashwantrao Pathrikar College of Pharmacy, Pathri.Phulambri, Chh. Sambhajinagar. 431111, India

DOI:

https://doi.org/10.22270/ajprd.v14i2.1734

Abstract

Elevated levels of one or more plasma lipids, including triglycerides, cholesterol, cholesterol esters, phospholipids, and/or plasma lipoproteins, including very low-density lipoprotein and decreased levels of high-density lipoprotein are indicative of a medical condition called hyperlipidemia. This elevation in plasma lipids is one of the primary risk factors for cardiovascular diseases.Statins and fibrates remain the main antihyperlipidemic drugs for the treatment of elevated plasma cholesterol and triglycerides, respectively, at the cost of major negative effects on the liver and muscles. Hyperlipidemia is the main risk factor for coronary heart disease.

 

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Published

2026-04-15

How to Cite

Rutuja Talekar, Nanasaheb Gorade, Sachin Jadhav, Pratiksha Chormage, Shivani Gadekar, Swati H.Tarkase, & Dr.Gajanan Sanap. (2026). An Antihyperlipidemic Agents Review for Atherosclerosis Treatment . Asian Journal of Pharmaceutical Research and Development, 14(2), 174–181. https://doi.org/10.22270/ajprd.v14i2.1734