Pharmacogenomics of Anticancer Medicines: Mechanisms, Clinical Applications, and Future Perspectives

Authors

  • Devarajan S Department of Pharmacology, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India.
  • Gayathri A Department of Pharmacy Practice, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India.
  • Dr.Shri Vijaya Kirubha T Department of Pharmacognosy, Principal, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India

DOI:

https://doi.org/10.22270/ajprd.v13i6.1672

Abstract

Pharmacogenomics has become a vital tool in oncology, guiding the selection and dosing of anticancer medicines based on genetic makeup. Genetic variations in drug- metabolizing enzymes, transporters, and target genes play a pivotal role in determining therapeutic response and toxicity [1]. This review summarizes current understanding of pharmacogenomics in cancer treatment, highlighting key mechanisms, biomarkers, and clinical applications [2]. It also discusses challenges in implementing pharmacogenomics in routine practice, particularly in developing countries, and suggests future directions for integrating pharmacogenomics into personalized medicine strategies [3].

 

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Author Biographies

Devarajan S, Department of Pharmacology, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India.

Department of Pharmacology, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India.

Gayathri A, Department of Pharmacy Practice, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India.

Department of Pharmacy Practice, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India.

Dr.Shri Vijaya Kirubha T, Department of Pharmacognosy, Principal, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India

Department of Pharmacognosy, Principal, Mother Terasa College of Pharmacy, Illupur, Pudukkottai, India

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Published

2025-12-15

How to Cite

Devarajan S, Gayathri A, & Dr.Shri Vijaya Kirubha T. (2025). Pharmacogenomics of Anticancer Medicines: Mechanisms, Clinical Applications, and Future Perspectives. Asian Journal of Pharmaceutical Research and Development, 13(6), 183–184. https://doi.org/10.22270/ajprd.v13i6.1672

Issue

Vol. 13 No. 6 (2025): Volume 13 Issue 6 Nov.- Dec. 2025

Section

Review Articles

License

Copyright (c) 2025 Devarajan S, Gayathri A, Dr.Shri Vijaya Kirubha T

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