Approaches For Transdermal Drug Delivery System:A Review

Authors

  • Thakre Snehal Department of Pharmaceutics, Shri.D.D.Vispute College of Pharmacy and research center, New Panvel
  • Madhuri Shinde Department of Pharmaceutics, Shri.D.D.Vispute College of Pharmacy and research center, New Panvel

Keywords:

Bioavailability, Dosing frequency, Hepatic first pass metabolism, Transdermal drug Delivery system

Abstract

As the oral route of drug delivery system shows number of side effects such as gastric irritation, fluctuation in drug level in plasma, hepatic first pass metabolism.The Transdermal drug delivery system (TDDS) provides the effective way to deliver the drug directly in systemic circulation and hence increase in therapeutic effect of the drug. Topical administration of therapeutic agents offers many advantages over conventional oral and other routes of drug delivery.Transdermal administration of drugs is an another way of administration that can significantly deliver the larger molecules in potent quantities that overcome the problem with the oral administration such as poor bioavailability due to first pass metabolism and gastric irritation.To improve the effectiveness of the transdermal drug delivery system, number of approaches are emerged,which will increase the absorption of the drug in systemic circulaton and reduction in dosing frequency.This review article describes the number of approaches for transdermal drug delivery system.

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Published

2014-03-01

How to Cite

Snehal, T., & Shinde, M. (2014). Approaches For Transdermal Drug Delivery System:A Review. Asian Journal of Pharmaceutical Research and Development, 2(2), 1–12. Retrieved from https://ajprd.com/index.php/journal/article/view/160

Issue

Volume 2nd Issue 2nd March-April 2014

Section

Review Articles

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