Recent Advances in Green Analytical Chemistry

Authors

  • Payal R. Khairmode Department of Pharmaceutical Quality Assurance, SND College of Pharmacy, Babhulgaon (Yeola), India.
  • Ramdas B. Darade Department of Pharmaceutical Quality Assurance, SND College of Pharmacy, Babhulgaon (Yeola), India.

DOI:

https://doi.org/10.22270/ajprd.v13i1.1530

Keywords:

Ziprasidone Hydrochloride, UV-Spectroscopy, method development, pharmaceutical analysis, quality control, HPLC comparison, atypical antipsychotic, schizophrenia, bipolar disorder.

Abstract

This review article provides a comprehensive overview of the development and validation of a UV-Spectroscopic method for the quantification of Ziprasidone Hydrochloride (HCl) in both bulk and marketed formulations. Ziprasidone HCl, an atypical antipsychotic used in the treatment of schizophrenia and bipolar disorder, requires precise analytical methods for its quantification due to its clinical importance. The study emphasizes the methodological aspects, including the selection of solvents, determination of the maximum absorbance wavelength (λmax), and the preparation of standard solutions. The validation process covers key parameters such as linearity, accuracy, precision, specificity, and sensitivity. The method's specificity is confirmed by the lack of interference from common excipients. This UV spectroscopic method is concluded to be simple, reliable, cost-effective, and suitable for routine quality control analysis of Ziprasidone HCl in pharmaceutical preparations. The article also includes a review of the latest literature on analytical methods for Ziprasidone HCl, highlighting recent advancements and comparisons with other techniques such as HPLC.

Downloads

Download data is not yet available.

Author Biographies

Payal R. Khairmode, Department of Pharmaceutical Quality Assurance, SND College of Pharmacy, Babhulgaon (Yeola), India.

Department of Pharmaceutical Quality Assurance, SND College of Pharmacy, Babhulgaon (Yeola), India.

Ramdas B. Darade, Department of Pharmaceutical Quality Assurance, SND College of Pharmacy, Babhulgaon (Yeola), India.

Department of Pharmaceutical Quality Assurance, SND College of Pharmacy, Babhulgaon (Yeola), India.

References

H. Malinsa, in E. Roth (Falters, Farnesyls VL. Reviews 00 Analytical Chemistry, Las additions de physique, Paris, France. 1987:49-64.

G. Pimentel, Opportunities in Chemistry, National Academy Press, Washington DC, USA, 1985.

M. de la Guardia, J. Ruzicka. Analyst (Cambridge, UK) 120 (1995) 17N.

P.T. Anastas, Crit. Rev. Anal Chem. 29 (1999) 167.

M. de la Guardia, K.D. Khalaf. V. Carbonell. A. Morales-Rubio, Anal. Chim. Acta 308 (1995) 462.

M. de la Guardia, K.D. Khalaf RA. Hasan, A. Morales-Rubio. Carbonell, Analyst (Cambridge. UK) 120 (1995) 231.

M. de la Guardia, J. Braz. Chem. Soc. 10 (1999) 429.

A. Abu-Sumra 15. Morris, S.R. Kostyohann. Anal. Chem. 47 (1975) 1475.

M.ID. Luque de Castro, M.M. Jiménes Carmona Trends Anal. Chem. 19 (2000) 221.

BE. Richter. RA. Jones, L. Emell, N.L. Posture, N. Avalonia, C. Pohl. Anal. Chem. 68 (1996) 1033.

RE Belardi, J. Puwlisaya, Pollute. Res. J. Canada 23 (1989) 179.

E. Baltussen, P. Sandra. F. David C.J. Cromer’s. Microcol, Sep. 11(1999) 737.

H. L. P.K. Dasgupta, Anal. Chem. 68 (1996) 1817.

M. Ma. F.F. Cantwell. Anal Chem. 70 (1998) 3912 1141.

IH. Watanabe, H. Tanaka, Talanta 25 (1978) 385.

Ruzicka. Elhi. Hansen. Flow Injection Analysis, Wiley, New York,1998.

K. Yoshinari, H. Waki, S. Ohashi, Talauuta 23 (1976) 449.

Ruzicka. GD. Marshall, Anal. Chim. Acta 237 (1990) 129.

B.F. Res. M.F. Giné, EAG. Zagato, JLF.C. Lima. RA. Lapa. Anal, Chim. Acta 293 (1994) 129.

A. Marta. N. Graber. HM. Widmer. Sers. Actuators. 1 (1990) 244.

Ruzicka. Analyst (Cambridge, UK) 12 (2000) 1053.

Curylo, W. Werenski, J. Namesake, Pul. 1. Environ. Stud. 16(2007) 5.

G. Xiong. B. Tang. X. He. M. Zhan, Z. Zhang, Z. Zhang, Talanta 48 (1999) 33.

Beck K. Totuche. L. Kögel-Krasner, Chennesphere 71 (2008).

D.E. Breithaupt. Food Chem. 86 (2004).

Published

2025-02-15

How to Cite

Khairmode, P. R., & Darade, R. B. (2025). Recent Advances in Green Analytical Chemistry. Asian Journal of Pharmaceutical Research and Development, 13(1), 231–237. https://doi.org/10.22270/ajprd.v13i1.1530