Frequency analysis of subgroup blood typing and Cis-AB type

Authors

  • Youngdu Baek Dept. of Biological Laboratory Science, Daegu Health College, Daegu, Korea
  • Cheolin Park Dept. of Biological Laboratory Science, Daegu Health College, Daegu, Korea

DOI:

https://doi.org/10.22270/ajprd.v11i2.1241

Keywords:

Transfusion, Cis-AB, antigenicity, side effects, blood subtypes.

Abstract

The purpose of this study is to prevent side effects of transfusion by analyzing the frequency of subtype blood types in blood type tests. Of the 19,800 cases, 128 (0.59%) cases were classified as subtypes. The distribution of subtype detection in K University Hospital was classified as Cis-AB (39 cases, 30.5%), A₂ (25 cases, 21.6%), A₂B (24 cases, 20.7%), A₁B (13 cases, 11.2%), A₃ (11 cases, 9.5 cases) %), B₃(9 cases, 7.8%), Ag(3 cases, 2.6%), Ax(1 case, 0.95%), Ay(1 case, 0.9%), Bx(1 case, 0.9%), Bel(1 case, 0.9%). Am, Az, and Bm were not detected at all. These subtype blood types are caused by quantitative and qualitative variants of antigenicity on the surface of red blood cells. Finally, the examiner should select blood that matches the patient's blood type and select blood that is not abnormal in the examination and transfuse it to prevent side effects of transfusion in advance.

 

Downloads

Download data is not yet available.

Author Biographies

Youngdu Baek, Dept. of Biological Laboratory Science, Daegu Health College, Daegu, Korea

Dept. of Biological Laboratory Science, Daegu Health College, Daegu, Korea

Cheolin Park, Dept. of Biological Laboratory Science, Daegu Health College, Daegu, Korea

Dept. of Biological Laboratory Science, Daegu Health College, Daegu, Korea

References

1. Lee JY, OH DJ, PARK YM. The Frequency and Distribution of the ABO Subgroups in Korean Blood Donors. Korean J Blood Transfus. 2010; 3(1):223~229.
2. Heo WY, Chung YN, Kim TY, Yu H, Bae JC, Kim H, Cho D.Analysis of ABO grouping discrepancies among patients from a tertiary hospital in Korea. TransfusApher Sci.2021;60(6):103230. doi: 10.1016
3. Lee, JI, KO SB. Adsorption & Elution methods for solving ABO subgroup discrepancy cases Korean J Blood Transfus. 2011; 2(1):40-40.
4. Park MS, Cheon SJ, Lee CH, Cho D. Diverse Phenotypes of Cis-AB Blood Group and Transfusion Strategy. Korean J. Blood Transfus. 2016; 304-306.
5. Choi BY, Uhm HK, Kim KH. A Study on A Subgroup of ABO Blood Groups in Koreans = A Study on A Subgroup of ABO discrepancy Group in Koreans Korean J. Blood Transfus2001; 7(4):59-62.
6. Kim HN, Lee HJ, Choi GR. Characteristics of Intron 6 Gene Sequences of Korean cis-AB Blood Type Korean J Blood Transfus. 2010; (6):230-235.
7. Woo CM, Lee HJ, Kwak HS, Shin SW, Kwon JY. Mismatched Transfusion Reaction in cis-AB Patient - A case report. Transplant Med. 2006; 3(2):632-637.
8. Seo DH, Kim SY, Kim JY, Park SS, Lee JB. Molecular Genetic Analysis of Korean B Subgroup Blood Types.Korean J Blood Transfus2005; 4(1):280-284.
9. Huang H, Jin SL, Xi W, Lu Q, Qian C, Wang X. Molecular genetic analysis of weak ABO subgroups in the Chinese population reveals ten novel ABO subgroup alleles.Blood Transfus. 2019; 17(3): 217–222.
10. Ammaranond P, Sriyarak J. Saejong S, Deesin P, Seereemaspun A, Rojanathanes. Enhanced Agglutination Reaction of ABO Subgroups by Gold Nanoparticle Solution: Implication for Identification of ABO Subgroups.Blood Transfus. 2011;24(2):77-83.
11. Chun S, Ryu MR, Cha SY, Seo JY, Cho D. ABO Mistyping of cis-AB Blood Group by the Automated Microplate Technique. Transfus Med Hemother. 2018; 45(1):5-10
12. Shin E, Kim H, Hur M, Lee H, Sohn IS, Park KU, Seo DH. Cis-AB showing discrepant results across different automated and manual methods: a case report and review of the literature. ClinChem Lab Med. 2023 Feb 24. doi: 10.1515/cclm-2023-0085
13. Cho D, Kim SH, Jeon MJ, Choi KL, Kee SJ, Shin MG, Shin JH, Suh SP, Yazer MH, Ryang DW. The serological and genetic basis of the cis-AB blood group in Korea. Vox Sang. 2004; 87(1):41-3.
14. Kolokolova GP. The forensic medical significance of cis-AB group in the AB0 system and its diagnostics in the traces of human discharges. Sud Med Ekspert. 2003; 46(5):43-7.

Published

2023-04-14

How to Cite

Baek, Y., & Park, C. (2023). Frequency analysis of subgroup blood typing and Cis-AB type. Asian Journal of Pharmaceutical Research and Development, 11(2), 1–5. https://doi.org/10.22270/ajprd.v11i2.1241

Issue

Vol. 11 No. 2 (2023): Volume 11 Issue 2 March - April. 2023

Section

Research Articles

AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).