Anti diabetic activity of Cynodon dactylon Linn In streptozotocin induced Diabetic Rats and its comparison with some standard flavonoids

Authors

  • Naveen Garg Research Scholar, Bhupal Nobles’ University Udaipur (Raj.) 313001
  • Amit Bhargava Assistant Professor Faculty of pharmacy, Bhupal Nobles’ University Udaipur (Raj.) 313001

DOI:

https://doi.org/10.22270/ajprd.v11i1.1212

Keywords:

cynodon dactylon, Streptozotocin, Flavonoids

Abstract

The aim of present investigation is to evaluate Antidiabetic activity of hydroalcohol extract of whole plant of cynodon dactylon Linn. In streptozotocin induced diabetic rats. Treatment with Cynodon dactylon hydro alcohol extract at two different dose 200 mg/kg and 400 mg/kg and its comparison with standard drug gilbencLinnide at dose of 5 mg/g and some flavonoids i.e. quercertin, kaempferol and epicatichin each at dose of 100mg/kg for 15 days, after induction of diabetes by streptozotocin 50 mg/kg , caused significant decrease in level of tri glycerides, total cholesterol and significantly increase in level of HDL and body weight compared to disease control group. It is furthermore Cynodon dactylon Linn at dose of 200mg/kg and 400mg/kg shows more significant result than some of standard flavonoids. Thus, whole plant of Cynodon dactylon Linn. may have potential Antidiabetic agent.

 

 

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Author Biographies

Naveen Garg, Research Scholar, Bhupal Nobles’ University Udaipur (Raj.) 313001

Research Scholar, Bhupal Nobles’ University Udaipur (Raj.) 313001

Amit Bhargava, Assistant Professor Faculty of pharmacy, Bhupal Nobles’ University Udaipur (Raj.) 313001

Assistant Professor Faculty of pharmacy, Bhupal Nobles’ University Udaipur (Raj.) 313001

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Published

2023-03-18

How to Cite

Garg, N., & Bhargava, A. (2023). Anti diabetic activity of Cynodon dactylon Linn In streptozotocin induced Diabetic Rats and its comparison with some standard flavonoids. Asian Journal of Pharmaceutical Research and Development, 11(1), 63–68. https://doi.org/10.22270/ajprd.v11i1.1212