Prevalence and Evaluation of Complications in Valvular Heart Disease Patients In Tertiary Care Hospital

  • Amtul Rafeh Mariya Intern, PharmD, Aster Prime Hospital, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India
  • Arshiya Mubeen Batool Intern, PharmD, Aster Prime Hospital, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India
  • Sri Praneeth Polamuri Dept. of Cardiology, Care Hospital, Hyderabad, Telangana, India
  • Anupama Koneru Professor & Principal, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India
  • S. P Srinivas Nayak Assistant Professor, Dept. of Pharmacy Practice, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Abstract

Background: One of the major outcomes of valvular heart disease have been chronic complications that in turn have led to the reduced quality of life of patients. These complications have indeed caused immense burden on the health care system and has led to increased mortality rate. Objective: To determine prevalence rate and to evaluate complications of valvular heart disease patients. Methods: This is a cross sectional-based study carried out in a single hospital in Hyderabad, India. The survey was carried out over a year in India. The source of data collection was through case sheets and lab reports. Results: Of the total 102 subjects, valvular diseases were more prevalent in the age group of 51-60 and females were found to be more affected than males. Complications were less or equal to no after the procedure of valve replacement was performed in patients with severe cases though some patients showed complications even after surgery, but were stable after a long time of monitoring. 1% of valve prolapse cases were seen and 3% deaths due to the disease. St.jude mechanical valve of different sizes, 19 EPR biological valve and aortic valve implants were majorly used for valve replacement procedure. Conclusion: The study concludes that valvular diseases are more prevalent in the age group 51-60, and females were more affected by valvular diseases than males. Hypertension and diabetes mellitus were found to be the major comorbidities in valvular heart disease patients.


 

Keywords: Valve prolapse, Cardiac arrests, St.jude mechanical valve, EPR biological valve, Hypertension, Diabetes mellitus.

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Author Biographies

Amtul Rafeh Mariya, Intern, PharmD, Aster Prime Hospital, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Intern, PharmD, Aster Prime Hospital, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Arshiya Mubeen Batool, Intern, PharmD, Aster Prime Hospital, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Intern, PharmD, Aster Prime Hospital, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Sri Praneeth Polamuri, Dept. of Cardiology, Care Hospital, Hyderabad, Telangana, India

Dept. of Cardiology, Care Hospital, Hyderabad, Telangana, India

Anupama Koneru, Professor & Principal, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Professor & Principal, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

S. P Srinivas Nayak, Assistant Professor, Dept. of Pharmacy Practice, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

Assistant Professor, Dept. of Pharmacy Practice, Sultan-ul-Uloom College of Pharmacy, JNTU-Hyderabad, Telangana, India

References

1. Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. 2006 Sep 16;368(9540):1005-11. doi: 10.1016/S0140-6736(06)69208-8. PMID: 16980116
2. Kovacs AH, Harrison JL, Colman JM, Sermer M, Siu SC, Silversides CK. Pregnancy and contraception in congenital heart disease: what women are not told. J Am Coll Cardiol. 2008 Aug 12;52(7):577-8. doi: 10.1016/j.jacc.2008.05.013.
3. Aliga, Ragavendra R.; Eagle et al Practical Cardiology: Evaluation and Treatment of Common Cardiovascular Disorders, 2nd ed. Publisher: Lippincott Williams & Wilkins (LWW) 2008. p. 452
4. Otto CM, Bonow RO. Valvular Heart Disease: A Companion to Braunwald’s Heart Disease. 4th ed. Philadelphia, PA: Elsevier Saunders; 2014. P. 326-340
5. Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2017 on CDC WONDER Online Database, released December, 2018. Data are from the Multiple Cause of Death Files, 1999-2017, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. Accessed at http://wonder.cdc.gov/ucd-icd10.html on Oct 24, 2019.
6. Steven Agabegi, MD, Elizabeth Agabegi, MD, Mark D. Duncan, MD, Kelley Chuang, MDDiseases of the Cardiovascular system Section: Valvular Heart Disease in: Elizabeth D Agabegi; Agabegi, Steven S. (2008). Step-Up to Medicine (Step-Up Series). Hagerstwon, MD: Lippincott Williams & Wilkins. 2008. Chapter.1 p.55-100
7. Manjunath CN, Srinivas P, Ravindranath KS, Dhanalakshmi C. Incidence and patterns of valvular heart disease in a tertiary care high-volume cardiac center: a single center experience. Indian Heart J. 2014 May-Jun;66(3):320-6. doi: 10.1016/j.ihj.2014.03.010. Epub 2014 Apr 14. PMID: 24973838; PMCID: PMC4121759
8. Kar S. Outcomes of New-Generation Drug-Eluting Stents in Women with Acute Myocardial Infarction. Curr Cardiol Rep. 2019 Jan 10;21(1):2.
9. Centers for Disease Control and Prevention, National Center for Health Statistics. About Multiple Cause of Death, 1999–2020. CDC WONDER Online Database website. Atlanta, GA: Centers for Disease Control and Prevention; 2022. Accessed February 21, 2022.
10. Carapetis J.R. Rheumatic heart disease in developing countries. N Engl J Med. 2007;357:439–441.
11. Roberts W.C. Morphologic features of the normal and abnormal mitral valve. Am J Cardiol. 1983;51:1005–1028.
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Rafeh Mariya, A., Mubeen Batool, A., Polamuri, S. P., Koneru, A., & Srinivas Nayak, S. P. (2022). Prevalence and Evaluation of Complications in Valvular Heart Disease Patients In Tertiary Care Hospital. Asian Journal of Pharmaceutical Research and Development, 10(6), 30-37. https://doi.org/https://doi.org/10.22270/ajprd.v10i6.1187