Medicinal Plant Used Against Cancer: A Review
DOI:
https://doi.org/10.22270/ajprd.v10i4.1150Keywords:
Cancer, Anti-cancer agents, Medicinal Plants, Plant kingdom, etc.Abstract
Nowadays natural products are considered protective markers compared to synthetic products that are considered unsafe for human health and the environment. Although a large number of synthetic drugs have been added to the world of current pharmacopoeia, there is still no drug system in the world that has been able to solve all health problems, including diseases such as Cancer. The extracts from plants have played an important role in the development of clinically effective anti-cancer agents. The plant kingdom produces naturally occurring secondary metabolites that are being investigated for their anti-cancer activities leading to the development of new clinical drugs. Global results continue to identify new anticancer compounds from plants. In recent years out of fear of adverse effects, people have chosen to make greater use of natural cancer products. This review attempted to summarize a few plants in India and outside India that have anti-cancer activity.
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References
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2. Hassanpour SH, Dehghani M. Review of cancer from perspective of molecular. Journal of Cancer Research and Practice. 2017.
3. Hiatt H, Watson J. D. and Winsten J. A. Origins of human cancer. Book A. Incidence of cancer in humans; Book B. Mechanisms of carcinogenesis; Book C. Human risk assessment. Cold Spring Harbor Laboratory, Box 100, Cold Spring Harbor, NY 11724, USA 1977.
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5. Adam, René. “Introduction Loco regional Tumor Therapy.” Springer, Berlin, Heidelberg. (2015): 1-2.
6. Gospodarowicz, M. K, Brierley J. D, and Wittekind C. “TNM classification of malignant tumours.” John Wiley & Sons. (2017): 714-718.
7. Chanchal DK, Alok S, Rashi S, Bijauliya RK, Yadav RD and Sabharwal M. various medicinal plants used in the treatment of anticancer activity. International Journal of Pharmaceutical Sciences and Research. 2018; 9(4): 1424-29.
8. Agarwal D, Ranawat MS, Chauhan CS, Kamble R. Formulation and Characterization of Colon Targeted pH Dependent Microspheres Of Capecitabine For Colorectal Cancer. Journal of Drug Delivery and Therapeutics. 2013; 3(6):215-222
9. Nema R, Khare S, Jain P, Pradhan A, Gupta A, Singh D. Natural products potential and scope for modern cancer research. American journal of plant sciences, 2013; 4:1270-1277.
10. Kooti et al. Effective Medicinal Plant in Cancer Treatment, Complementary & Alternative Medicine. 2017; 22(4): 982-995.
11. Greenwell M and Rahman PKSM. Medicinal Plants: Their Use in Anticancer Treatment. International Journal of Pharmaceutical Sciences and Research. 2015; 6(10): 4103-12.
12. Al-Snafi AE. Chemical constituents and pharmacological activities of Ammi majus and Ammi visnaga-a review. Int J Pharm Ind Res. 2013; 3:257-265.
13. Bora KS, Sharma A. The genus Artemisia: a comprehensive review. Pharmaceutical Biology. 2011; 49:101-109.
14. Asgarpanah J, Ariamanesh A. Phytochemistry and pharmacological properties of Myrtus communis L. Indian Journal Traditional Knowledge. 2015; 14:82-87.
15. Akrout A, Gonzalez LA, Hajer El J. Antioxidant and antitumor activities of Artemisia campestris and Thymelaea hirsuta from southern Tunisia. Food and Chemical Toxicology. 2011; 49(2):342-47.
16. Poeckel D, Werz O. Boswellic acids: biological actions and molecular targets. Current Medicinal Chemistry. 2006; 13:3359-3369.
17. Yasumoto R, Kawanishi H, Tsujino T, et al. Clinical evaluation of long-term treatment using cernitin pollen extract in patients with benign prostatic hyperplasia. Clinical Therapeutics. 1995; 17:82-87.
18. Wang Y, Duan H, Yang H. A case-control study of stomach cancer in relation to Camellia sinensis in China. Surgical Oncology. 2015; 24:67-70.
19. Srivastava R, Ahmed H, Dixit RK, Saraf SA. Crocus sativus L. A comprehensive review. Pharmacognosy Reviews. 2010; 4:200-208.
20. Hussain AI, Rathore HA, Sattar MZ, Chatha SA, Sarker SD, Gilani AH. Citrullus colocynthis (L.) Schrad (bitter apple fruit): a review of its phytochemistry, pharmacology, traditional uses and nutritional potential. Journal of Ethnopharmacology. 2014; 155:54-66.
21. Tavakkol Afshari J, Rakhshandeh H, Zamani AR, Mahdavi Shahri N, Ghazezadeh L, Norozi M. Cytotoxicity effects of Citrullus colocynthis on Hep2 and L929 cell lines. Hakim Research Journal. 2005;8(2):47-54.
22. Hatam NA, Whiting DA, Yousif NJ. Cucurbitacin glycosides from Citrullus colocynthis. Phytochemistry. 1876;28:1268-1271.
23. Wasfi IA. Some pharmacological studies on Citrullus colocynthis. Journal of Herbs Spices & Medicinal Plants. 1994;2(2):65-79.
24. Ayyad SEN, Abdel-Lateff A, Alarif WM, Patacchioli FR, Badria FA, Ezmirly ST. In vitro and in vivo study of cucurbitacins-type triterpene glucoside from Citrullus colocynthis growing in Saudi Arabia against hepatocellular carcinoma. Environmental Toxicology & Pharmacology. 2012;33:245-251.
25. Tannin-Spitz T, Grossman S, Dovrat S, Gottlieb HE, Bergman M. Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells. Biochemical Pharmacology. 2007;73:56-67.
26. Escribano J, Alonso GL, Coca-Prados M, Fernandez JA. Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro. Cancer Letters. 1996; 100(12):23-30.
27. Abdullaev FI, Frenkle GD. Effect of saffron on cell colony formation and cellular nucleic acid and protein syntheses. Biofactors. 1992; 3:201-204.
28. Mousavi M, Baharara J, Asadi-Samani M. Anti-angiogenesis effect of Crocous sativus L. extract on matrix metalloproteinase gene activities in human breast carcinoma cells. Journal of HerbMed Pharmacology. 2014; 3:101-105.
29. Aung HH, Wang CZ, Ni M, et al. Crocin from Crocus sativus possesses significant anti-proliferation effects on human colorectal cancer cells. Experimental Oncology. 2007;29:175-180.
30. Dubey KK, Ray AR, Behera BK. Production of demethylated colchicine through microbial transformation and scale-up process development. Process Biochemistry. 2008, 43(3), 251-7.
31. Sadooghi SD, Nezhad-Shahrokh-Abadi KH, Zafar Balanezhad S, Baharara J. Investigating the cytotoxic effects of ethanolic extract of Ferula assa-foetida resin on HepG2 cell line. Feyz. 2013; 17: 323-330.
32. Fallah Huseini H, Zahmatkash M, Haghighi M. A review on pharmacological effects of Curcuma longa L. (turmeric). Journal of molecular pathology. 2010;1(33):1-15.
33. Ayyadurai1 N, Valarmathy N, Kannan S, Jansirani D, Alsenaidy A. Evaluation of cytotoxic properties of Curcuma longa and Tagetes erecta on cancer cell line (Hep2). African Journal of Pharmacy and Pharmacology. 2013;7:736-739.
34. Ranjbari J, Alibakhshi A, Arezumand R, et al. Effects of Curcuma longa extract on telomerase activity in lung and breast cancer cells. Zahedan Journal of Research in Medical Sciences. 2014;16(10):1-6.
35. Mohammad P, Nosratollah Z, Mohammad R, Abbas A, Javad R. The inhibitory effect of Curcuma longa extract on telomerase activity in A549 lung cancer cell line. African Journal of Biotechnology. 2010; 9(6). http://www.ajol.info/index.php/ajb/article/view/78098. Accessed February 27, 2017.
36. Hosseinimehr SJ. A review of preventive and therapeutic effects of curcumin in patients with cancer. Journal of Clinical Excellence. 2014;2(2): 50-63.
37. Anand P, Sundaram C, Jhurani S, Kunnumakkara AB, Aggarwal BB. Curcumin and cancer: an “old-age” disease with an “age old” solution. Cancer Letters. 2008;267:133-164.
38. Guo C, Yang J. Antioxidant activities of Ferula assafoetida as determined by FRAP assay. Nutrition Research. 2003; 23: 1719-1726.
39. Valiahdi SM, Iranshahi M, Sahebkar A. Cytotoxic activities of phytochemicals from Ferula species. Daru Journal of Pharmaceutical Sciences. 2013; 21: 39-45.
40. Kooti W, Hasanzadeh-Noohi Z, Sharafi-Ahvazi N, Asadi-Samani M, Ashtary-Larky D. Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa). Chinese Journal of Natural Medicine. 2016; 14:732-745.
41. Khanahmadi MM, Naghdi Badi H, Akhondzadeh S, et al. A review on medicinal plant of Glycyrrhiza glabra L. Journal of Molecular Pathology. 2013; 2(46):1-12.
42. Hamta A, Shariatzadeh SMA, Soleimani Mehranjani SMA, Fallah Huseini H, Hosseinabadi F. The cytotoxic effects of Glycyrrhiza glabra L. root extract on 4T1 cell line derived from BALB/c mice mammary tumors. Journal of Medicinal Plant. 2014; 2(50):92-103.
43. Harwansh RK, Patra KC, Pareta SK, Singh J. Pharmacological studies on Glycyrrhiza glabra. Pharmacology online. 2011;2:1032-1038.
44. Baltina LA. Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine. Curr Med Chem. 2003;10:155-171.
45. Rossi T, Castelli M, Zandomeneghi G, Ruberto A, Benassi L, Magnoni C. Selectivity of action of glycyrrhizin derivatives on the growth of MCF-7 and HEP-2 cells. Anticancer Res. 2003; 23(5A):3813-3818.
46. Nourazarian SM, Nourazarian A, Majidinia M, Roshaniasl E. Effect of root extracts of medicinal herb Glycyrrhiza glabra on HSP90 gene expression and apoptosis in the HT-29 colon cancer cell line. Asian Pac J Cancer Prev. 2015;16:8563-8566.
47. Raval ND, Pandya TN. Pharmacognostic study of Lepidium sativum Linn (Chandrashura). Ayu. 2011;32:116-119.
48. Al-FatimiM, Friedrich U, Jenett-Siems K. Cytotoxicity of plants used in traditional medicine in Yemen. Fitoterapia. 2005;76: 355-358.
49. Aslani E, Naghsh N, Ranjbar M. Cytotoxic effects of hydroalcoholic extracts of cress (Lepidium sativum)—made from different stages of the plant—on k562 Leukemia cell line. Hormozgan Med J. 2015;18:411-419.
50. Servatyari K, Ahmadi A, Kashefi H, Menbari MN, Rostami R, Moloudi MR. The effects of hydroalcoholic extract of Medicago sativa on liver functional test, blood biochemical and coagulation system parameters in male rat. Sci J Kurdistan Univ Med Sci. 2017;21(6):16-26. https://sjku.muk.ac.ir/article-1-2819-en.pdf. Accessed February 27, 2017
51. Huyghe C, Bertin E, Landry N. Medicinal and nutraceutical uses of alfalfa (Medicago sativa L). A review. In: Acharya SN, Thomas JE, eds. Advances in Medicinal Plant Research. Trivandrum, India: Research Signpost; 2007:147-172.
52. Singh Bora K, Sharma A. Phytochemical and pharmacological potential of Medicago sativa: a review. Pharm Biol. 2011;49:211-220.
53. Kooti W, Hasanzadeh-Noohi Z, Sharafi-Ahvazi N, Asadi-Samani M, Ashtary-Larky D. Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa). Chin J Nat Med. 2016; 14:732-745.
54. Tabasi NS, Khajavi-Rad A, Mahmoudi M, et al. The effects of Nigella sativa ethanolic extract on proliferation and apoptosis of renal cell carcinoma ACHN cell line. J Shahrekord Univ Med Sci. 2010;12(3):7-14.
55. Ait Mbarek L, Ait Mouse H, Elabbadi N, et al. Anti-tumor properties of blackseed (Nigella sativa L.) extracts. Braz J Med Biol Res. 2007;40:839-847.
56. Gali-Muhtasib H, Diab-Assaf M, Boltze C, et al. Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. Int J Oncol. 2004;25:857-866.
57. Shoeib AM, Elgayyar M, Dudrich P, Bell J. In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. Int J Oncol. 2003;22:107-113.
58. Muhtasib H, Roessner A, Schneider R. Thymoquinone: a promising anti-cancer drug form natural sources. Int J Biochem Cell Biol. 2006;38:1249-1253.
59. Khalife R, Hodroj MH, Fakhoury R, Rizk S. Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro. Planta Med. 2016;82:312.
60. Elkady AI, Hussein RA, El-Assouli SM. Mechanism of action of Nigella sativa on human colon cancer cells: the suppression of AP-1 and NF-kB transcription factors and the induction of cytoprotective genes. Asian Pac J Cancer Prev. 2015;16:7943-7957.
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Published
2022-08-14
How to Cite
Srivastava, R., & Tiwari, P. (2022). Medicinal Plant Used Against Cancer: A Review. Asian Journal of Pharmaceutical Research and Development, 10(4), pdf. https://doi.org/10.22270/ajprd.v10i4.1150
Issue
Section
Review Articles
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