Review on process validation of Amoxicillin Potassium Clavulanate Dry Syrup
DOI:
https://doi.org/10.22270/ajprd.v10i4.1146Keywords:
Amoxicillin, Clavulanate , Spectrophotometer, Dry syrup, Validation.Abstract
Modern medicines for human use are required to comply with specific standards and regulation set forth by the concerned authorities. A simple and sensitive UV spectrophotometric method was developed and validated for the simultaneous determination of Potassium Clavulanate (PC) and Amoxicillin. As complementary of this work, an assay method for amoxicillin and potassium clavulanate mixtures was developed and validated; stress-testing and stability studies of amox/clav mixtures was carried out under specified conditions according to ICH and analyzed by using validated stability-indicating assay and related substances methods. Aim of this study was to test the validation of derivative spectrophotometric method in simultaneous determination the content amoxicillin and clavulanate potassium in dry syrup by derivative spectrophotometric method with zero crossing technique, in buffer phosphate pH 4,4-methanol (91:9) mixture.
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23. Kumar, Roshan, Purabi Saha, Priyatosh Pathak, Ramayani Mukherjee, Abhishek Kumar, and Rakesh Kumar Arya. "Evolution Of Tolbutamide In The Treatment Of Diabetes Mellitus." Jour. of Med. P’ceutical & Alli. Sci 9.
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29. Kumar, Roshan, and Purabi Saha. "A Review on Artificial Intelligence and Machine Learning to Improve Cancer Management and Drug Discovery." International Journal for Research in Applied Sciences and Biotechnology (2022); 9(3):149-156.
30. Kumar, S., S. P. Yadav, G. Chandra, D. S. Sahu, R. Kumar, P. S. Maurya, D. K. Yadav, V. JaiswaL, and K. Ranjan. "Effect of dietary supplementation of yeast (Saccharomyces cerevisiae) on performance and hemato-biochemical status of broilers." (2019): 15-19.
31. Mukkamala, Ramesh, Roshan Kumar, Sanjay K. Banerjee, and Indrapal Singh Aidhen. "Synthesis of Benzyl C‐Analogues of Dapagliflozin as Potential SGLT2 Inhibitors." European Journal of Organic Chemistry 2020; 12:1828-1839.
32. Anubhav, Saha Purabi Dubey, Kumar Dr Sanjay, and Kumar Roshan. "Evaluation of Enzyme Producing K. Pneumoniae and Their Susceptibility to Other Anti-Biotics." International Journal of Innovative Science and Research Technology, 2022; 7(5):351-353.
33. Saha, P., Kumar, A., Bhanja, J., Shaik, R., Kawale, A. L., & Kumar, R. A Review of Immune Blockade Safety and Antitumor Activity of Dostarlimab Therapy in Endometrial Cancer. International Journal for Research in Applied Sciences and Biotechnology, 2022; 9(3):201-209.
34. Kumar, Roshan, E. Keshamma, Shravan Kumar Paswan, Purabi Saha, Utkarsh Trivedi, Anurag Chourasia, and Mihir Otia. "Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis." Journal for Research in Applied Sciences and Biotechnology (2022); 1(2): 35-42.
35. Singh, Yogendra, Shravan Kumar Paswan, Roshan Kumar, Mihir Kedarbhai Otia, Smita Acharya, Devinder Kumar, and E. Keshamma. "Plant & Its Derivative Shows Therapeutic Activity on Neuroprotective Effect." Journal for Research in Applied Sciences and Biotechnology (2022); 1(2):10-24.
36. Richard Owusu Nyarko, R. Roopini, Velicharla Raviteja, Chinaza Godswill Awuchi, Roshan Kumar, Erwin Martinez Faller, Elrey Librea Navarro, Edward Boateng, Ivan Kahwa, Paul Owusu Boateng, Christian Asum, and Purabi Saha. 2022. “Novel Sars-CoV-2 Variants & Therapeutic Effects”. Journal for Research in Applied Sciences and Biotechnology 1 (2):25-34. https://doi.org/10.55544/jrasb.1.2.3.
37. Kumar, Roshan, E. Keshamma, Shravan Kumar Paswan, Purabi Saha, Utkarsh Trivedi, Anurag Chourasia, and Mihir Otia. "Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis." Journal for Research in Applied Sciences and Biotechnology, (2022); 1(2): 35-42.
38. Harding MS, Williams PO, Ayrton J: Pharmacology of cefuroxime as the 1-acetoxyethyl ester in volunteers. Antimicrob Agents Chemother 25: 1984, 78-82.
39. Mandell GL, Petri WA: Antimicrobial agents: Penicillin, cephalosporins, and other ]3-1actam antibiotics. In Hardman JG, Limbird LE (eds): Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 9th ed. New York: McGraw-Hill, 1996, pp 1074-1076.
40. Kees F, Lukassck U, Naber KG, Grobccker H: Com parative investigations on the bioavailability of cefuroxime axetil. Arzneim Forsch 41 1999, 843-846.
2. Akhavan BJ, Khanna NR, Vijhani P. StatPearls [Internet]. StatPearls Publishing; Treasure Island (FL): Aug 17, 2021.
3. Awuchi, Chinaza Godswill, Ikechukwu Otuosorochi Amagwula, Priyanka Priya, Roshan Kumar, Umama Yezdani, and Mohammad Gayoor Khan. "Aflatoxins in foods and feeds: A review on health implications, detection, and control." Bull. Environ. Pharmacol. Life Sci 9 (2020): 149-155.
4. Umama, Yezdani, G. Venkatajah, Rav Shourabh, Roshan Kumar, Arvind Verma, Ayush Kumar, and Md Khan Gayoor. "Topic-The scenario of pharmaceuticals and development of microwave as; sisted extraction technique." World J Pharm Pharm Sci, (2019); 8(7):1260-1271.
5. Kumar, Roshan, Purabi Saha, Priya Lokare, Kunal Datta, P. Selvakumar, and Anurag Chourasia. "A Systemic Review of Ocimum sanctum (Tulsi): Morphological Characteristics, Phytoconstituents and Therapeutic Applications." International Journal for Research in Applied Sciences and Biotechnology, (2022); 9(2):221-226.
6. Roshan, Kumar. "Priya damwani, Shivam kumar, Adarsh suman, Suthar Usha. An overview on health benefits and risk factor associated with coffee." International Journal Research and Analytical Review (2020) ; 7(2):237-249.
7. Sahana, Soumitra. "Purabi saha, Roshan kumar, Pradipta das, Indranil Chatterjee, Prasit Roy, Sk Abdur Rahamat." A Review of the 2019 Corona virus (COVID-19) World Journal of Pharmacy and Pharmaceutical science (2020) ; 9(9):2367-2381.
8. Bind, Amit, Saumya Das, Veena D. Singh, Roshan Kumar, Anurag Chourasia, and Purabi Saha. "Natural Bioactives For The Potential Management Of Gastric Ulceration." Turkish Journal of Physiotherapy and Rehabilitation 32, no. 3.
9. Dubey, Anubhav, Priyanka Yadav, Preeti Verma, and Roshan Kumar. "Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line." Journal of Drug Delivery and Therapeutics (2022) ;12(1):51-55.
10. Kumar, Roshan, and Anubhav Dubey. "Phytochemical Investication And Heptoprotective Evalution Acacia Rubica Extract Isonized And Paracetamol Indused Animal Toxicity." Turkish Journal of Physiotherapy and Rehabilitation 32, no. 3.
11. Saha, Purabi, Roshan Kumar, Richard Owusu Nyarko, Ivan Kahwa, and Paul Owusu. "Herbal Secondary Metabolite For Gastro-Protective Ulcer Activity With Api Structures." (2021).
12. Nyarko, Richard Owusu, Amit Prakash, Nayan Kumar, Purabi Saha, and Roshan Kumar. "Tuberculosis a globalized disease." Asian Journal of Pharmaceutical Research and Development (2021) ;9(1):198-201.
13. Raj, A., S. Tyagi, R. Kumar, A. Dubey, and A. C. Hourasia. "Effect of isoproterenol and thyroxine in herbal drug used as cardiac hypertrophy." Journal of Cardiovascular Disease Research (2021): 204-217.
14. Singh, Mukesh Kr, Ajay Kumar, Roshan Kumar, P. Satheesh Kumar, P. Selvakumar, and Anurag Chourasia. "Effects of Repeated Deep Frying on Refractive Index and Peroxide Value of Selected Vegetable Oils." International Journal for Research in Applied Sciences and Biotechnology, (2022) ;9(3): 28-31.
15. Sahana, Soumitra. "Roshan kumar, Sourav nag, Reshmi paul, Nilayan guha, Indranil Chatterjee. A Review on Alzheimer disease and future prospects." World Journal of Pharmacy and Pharmaceutical science (2020) ;9(9): 1276-1285.
16. Nyarko, Richard Owusu, Roshan Kumar, Shaina Sharma, Anurag Chourasia, Ayushmann Roy, and Purabi Saha. "Antibacterial Activity Of Herbal Plant-Tinospora Cordifolia And Catharnthus Roseus." (2022).
17. Sahana, Soumitra, Roshan Kumar, Sourav Nag, Reshmi Paul, Indranil Chatterjee, and Nilayan Guha. "A Review On Alzheimer Disease And Future Prospects." (2020).
18. Nyarko, R. O., P. Saha, R. Kumar, I. Kahwa, E. A. Boateng, P. O. Boateng, A. Christian, and A. Bertram. "Role of Cytokines and Vaccines in Break through COVID 19 Infections." Journal of Pharmaceutical Research International 33 (2021): 2544-2549.
19. Purabisaha, Roshan Kumar, Shrestha Sarkar3 Nikita Rawat, And Amit Prakash. "A Review On Novel Drug Delivery System." (2021).
20. Nyarko, Richard Owusu, Edward Boateng, Ivan Kahwa, and Paul Owusu Boateng. "A comparison analysis on remdesivir, favipiravir, hydroxychloroquine, chloroquine and azithromycin in the treatment of corona virus disease 2019 (COVID-19)-A Review." World J. Pharm. Pharm. Sci 9 (2020): 121-133.
21. Nyarko, R. O., E. Boateng, I. Kahwa, P. O. Boateng, and B. Asare. "The impact on public health and economy using lockdown as a tool against COVID-19 pandemic in Africa: a perspective." J Epidemiol Public Health Rev 5, no. 3 (2020).
22. Kumar, Roshan, Purabi Saha, Shrestha Sarkar, Nikita Rawat, And Amit Prakash. "A Review On Novel Drug Delivery System." IJRAR-International Journal of Research and Analytical Reviews (IJRAR) (2021); 8(1): 183-199.
23. Kumar, Roshan, Purabi Saha, Priyatosh Pathak, Ramayani Mukherjee, Abhishek Kumar, and Rakesh Kumar Arya. "Evolution Of Tolbutamide In The Treatment Of Diabetes Mellitus." Jour. of Med. P’ceutical & Alli. Sci 9.
24. Kumar, Roshan, Purabi Saha, Yogendra Kumar, Soumitra Sahana, Anubhav Dubey, and Om Prakash. "A Review on Diabetes Mellitus: Type1 & Type2." World Journal of Pharmacy and Pharmaceutical Sciences (2020) ; 9(1)0:838-850.
25. Daharia, Anju, Vinod Kumar Jaiswal, Kabya Pratap Royal, Himanshu Sharma, Anuj Kumar Joginath, Roshan Kumar, and Purabi Saha. "A Comparative review on ginger and garlic with their pharmacological Action." Asian Journal of Pharmaceutical Research and Development 10, no. 3 (2022): 65-69.
26. Kumar R, Jain A, Tripathi AK, Tyagi S. Covid-19 outbreak: An epidemic analysis using time series prediction model. In2021 11th international conference on cloud computing, data science & engineering (Confluence) 2021 Jan 28 (pp. 1090-1094). IEEE.
27. KUMAR, AYUSH. "The Scenario of Pharmaceuticals and Development of Microwave Assisted Extraction Techniques." (2019).
28. Saha, Purabi, Richard Owusu Nyarko, Priya Lokare, Ivan Kahwa, Paul Owusu Boateng, and Christian Asum. "Effect of Covid-19 in Management of Lung Cancer Disease: A Review." Asian Journal of Pharmaceutical Research and Development (2022) ; 10(3):58-64.
29. Kumar, Roshan, and Purabi Saha. "A Review on Artificial Intelligence and Machine Learning to Improve Cancer Management and Drug Discovery." International Journal for Research in Applied Sciences and Biotechnology (2022); 9(3):149-156.
30. Kumar, S., S. P. Yadav, G. Chandra, D. S. Sahu, R. Kumar, P. S. Maurya, D. K. Yadav, V. JaiswaL, and K. Ranjan. "Effect of dietary supplementation of yeast (Saccharomyces cerevisiae) on performance and hemato-biochemical status of broilers." (2019): 15-19.
31. Mukkamala, Ramesh, Roshan Kumar, Sanjay K. Banerjee, and Indrapal Singh Aidhen. "Synthesis of Benzyl C‐Analogues of Dapagliflozin as Potential SGLT2 Inhibitors." European Journal of Organic Chemistry 2020; 12:1828-1839.
32. Anubhav, Saha Purabi Dubey, Kumar Dr Sanjay, and Kumar Roshan. "Evaluation of Enzyme Producing K. Pneumoniae and Their Susceptibility to Other Anti-Biotics." International Journal of Innovative Science and Research Technology, 2022; 7(5):351-353.
33. Saha, P., Kumar, A., Bhanja, J., Shaik, R., Kawale, A. L., & Kumar, R. A Review of Immune Blockade Safety and Antitumor Activity of Dostarlimab Therapy in Endometrial Cancer. International Journal for Research in Applied Sciences and Biotechnology, 2022; 9(3):201-209.
34. Kumar, Roshan, E. Keshamma, Shravan Kumar Paswan, Purabi Saha, Utkarsh Trivedi, Anurag Chourasia, and Mihir Otia. "Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis." Journal for Research in Applied Sciences and Biotechnology (2022); 1(2): 35-42.
35. Singh, Yogendra, Shravan Kumar Paswan, Roshan Kumar, Mihir Kedarbhai Otia, Smita Acharya, Devinder Kumar, and E. Keshamma. "Plant & Its Derivative Shows Therapeutic Activity on Neuroprotective Effect." Journal for Research in Applied Sciences and Biotechnology (2022); 1(2):10-24.
36. Richard Owusu Nyarko, R. Roopini, Velicharla Raviteja, Chinaza Godswill Awuchi, Roshan Kumar, Erwin Martinez Faller, Elrey Librea Navarro, Edward Boateng, Ivan Kahwa, Paul Owusu Boateng, Christian Asum, and Purabi Saha. 2022. “Novel Sars-CoV-2 Variants & Therapeutic Effects”. Journal for Research in Applied Sciences and Biotechnology 1 (2):25-34. https://doi.org/10.55544/jrasb.1.2.3.
37. Kumar, Roshan, E. Keshamma, Shravan Kumar Paswan, Purabi Saha, Utkarsh Trivedi, Anurag Chourasia, and Mihir Otia. "Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis." Journal for Research in Applied Sciences and Biotechnology, (2022); 1(2): 35-42.
38. Harding MS, Williams PO, Ayrton J: Pharmacology of cefuroxime as the 1-acetoxyethyl ester in volunteers. Antimicrob Agents Chemother 25: 1984, 78-82.
39. Mandell GL, Petri WA: Antimicrobial agents: Penicillin, cephalosporins, and other ]3-1actam antibiotics. In Hardman JG, Limbird LE (eds): Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 9th ed. New York: McGraw-Hill, 1996, pp 1074-1076.
40. Kees F, Lukassck U, Naber KG, Grobccker H: Com parative investigations on the bioavailability of cefuroxime axetil. Arzneim Forsch 41 1999, 843-846.
Published
2022-08-14
How to Cite
Devi, A., Kumar, S., Jeet, K., Sharma, V., & Chaudhary, A. (2022). Review on process validation of Amoxicillin Potassium Clavulanate Dry Syrup. Asian Journal of Pharmaceutical Research and Development, 10(4), 102–107. https://doi.org/10.22270/ajprd.v10i4.1146
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Section
Review Articles
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