The Evaluation of Anti Microbial Activity of Classical Siddha Medicine Seenthil Choornam

  • Lalitha Sunanna PG Scholar, Department of Pothu Maruthuvam, Government Siddha Medical College, Palayamkottai Tirunelveli, Tamil Nadu, PIN- 627002
  • A. Manoharan Professor and HOD, Department of Pothu Maruthuvam, Government Siddha Medical College, Palayamkottai Tirunelveli, Tamil, Nadu, PIN- 627002

Abstract

Seenthil Choornam is a Classical Siddha medicine having its ingredients with herbal andanimal origin. The raw drugs- Seenthil (Tinospora cordifolia .sp), Karisalai (Ecilpta Albasp), and Poonagam(Eudriluseugeniae.sp) were purified and combined as per theliterature. Aim: - The aim of the study is to evaluate the anti-microbial activity of Seenthil Choornam.


Materials and methods: - Raw drugs were collectedfrom Keralaand Tamilnadu .The identification and authentication of plant


drugs were obtained fromGovt.Siddha Medical College, Palayamkottai. The authentication of Poonagam (Eudrilus eugeniaesp.) was obtained from Advanced Centre of Environmental Studies and Sustainable Development-Inter University Centre – Mahatma Gandhi University, Kottayam...Anti-bacterial and Anti-fungal activity of aqueous and ethanolic extract of drug is studied for its activity against four Gram positive, three Gram negative bacteria and five fungi in concentrations of 25ul, 50ul, 75ul and 100ul , using Disc diffusion method. The standard drug for comparison of anti-bacterial activity is Streptomycin and for Anti-fungal activityis Fluconazole. Result:- The aqueous extract of drug in concentrations of 75ul & 100ul has  zone of inhibition against Bacillus subtilis (G+ve)- (19mm, 21mm) ,Enterococcusfeacalis-(G+ve)in conc.75ul&100ul - (11mm, 13mm), Klebsiella pneumonia (G-ve) in conc.75ul &100ul- (11mm ,13mm) , Staphylococcus aureus (G+ve)in conc. 75ul &100ul-(10mm,11mm) and towards fungus -Aspergillus flavusin conc. 75ul &100ul ( 12mm, 13mm ) .From the above study it is evident that the classical medicineSeenthil Choornamis effective against human pathogens.


        

Keywords: Anti bacterial, Anti-fungal, SeenthilChoornam.

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Author Biographies

Lalitha Sunanna, PG Scholar, Department of Pothu Maruthuvam, Government Siddha Medical College, Palayamkottai Tirunelveli, Tamil Nadu, PIN- 627002

PG Scholar, Department of Pothu Maruthuvam, Government Siddha Medical College, Palayamkottai Tirunelveli, Tamil Nadu, PIN- 627002

A. Manoharan, Professor and HOD, Department of Pothu Maruthuvam, Government Siddha Medical College, Palayamkottai Tirunelveli, Tamil, Nadu, PIN- 627002

Professor and HOD, Department of Pothu Maruthuvam, Government Siddha Medical College, Palayamkottai Tirunelveli, Tamil, Nadu, PIN- 627002

References

1. Assam AJ P ,Dzoyem J P ,Piem C A and Penlap V B (2010 ), “In vitro Antibacterial Activity and Acute toxicity Studies of Aqueous-Methanol extract of Sidarhombifolia Linn(Malvaceae)”,BMC Complementary and alternative Medicine ,2010; 10(40):1-7.
2. Bauer A W .Kirby W M M, Sherri J C & Turck M. Antibiotic susceptibility testing by a standardized single disk method .Amer .I. C/in. Pathol.45:493-6. (Depts. Microbiology and Medicine .University, Washington .Sch .Med .Seattle .WA)
3. 3.Bindu Modi , Kabitha kumari Shah ,Jiban Shreshta , Prakash Shreshta , Anju Banset ,Injila Tiwari, Surya Prasad Aryal ,Morphology ,Biological Activity ,Chemical Composition and Medicinal value of Tinospora cordifolia (willd ) Miers,2021; 3(1):36-53.
4. Certificate of Zoological Authenticity, Advanced center of environmental Studies and Sustainable Development (ACESSD) –An Inter University Centre.
5. Kohner PC, Rosenblatt JE, Cocker ill FR, 1994.Comparison of agar dilution, broth dilution and Disk diffusion testing of Ampicillin against Haemophilus sp.by using in house and commercially prepared media J.Clin.Microbiol.1994; 32:1594-96.
6. Liton Rama Md, A review on traditional uses, phytochemistry and Pharmacological properties of Ecilpta Alba (Linn) Hassk-an innumerable medicinal plant.
7. Mathebe.M.C, Nickolova.R.V , Lall N,Antibacterial activities of medicinal plants used for the treatment ofdiaeehoea in Limpopo Province ,South Africa , Journal of Ethanopharmacology.2006; 105:289-293.
8. Mohan R.C, Agathiyar Paripooranam-400.213, 7, N.G.O.Colony, Vadapazhani, Chennai -26 Thamarai Noolagam, 2012 January
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Sunanna, L., & Manoharan, A. (2022). The Evaluation of Anti Microbial Activity of Classical Siddha Medicine Seenthil Choornam. Asian Journal of Pharmaceutical Research and Development, 10(3), 24-29. https://doi.org/https://doi.org/10.22270/ajprd.v10i3.1121