Antagonistic Activity of Agaricuscampestris mushroom Extracts Against some Human Pathogenic Bacterial Species

  • Shatha Ali Shafiq Department of Biology, College of Science, Mustansiriyah university /Baghdad-Iraq
  • Rasha Salam Sahib Al-Rafidain university college –Medical Laboratory Techniques/Baghdad-Iraq

Abstract

The present study focused on the evaluation of Agaricuscampestris mushroom extracts activity against four clinical isolates Escherichia coli; Pseudomonas aerginosa; Staphylococcus haemolyticus and Staphylococcus aureus. Agaricuscampestris mushroom extracts varied in their antimicrobial activity. The intensity of the antimicrobial effect is dependent upon the solvent , concentration of the mushroom extract and the organism being tested against .Therefore, The hot water and ethanolic extract 96%showed maximum inhibition at high concentrations specially at  500 mg/ml  concentration( 17, 16, 19, 16  ) mm and ( 20,21,19,20) against E. coli , Pseudomonas aerginosa; Staphylococcus aureus and Staphylococcus haemolyticus respectively compared with methanolic extract . The ethyl acetate  extract of the   powder mushroom  of Agaricuscampestris was analyzed to 9 chemical compounds belonged to fatty acids and their derivatives and included :-Nonadecane, Pentacosane, Octadecane, Heptadecane, Heneicosane, Hexadecane, 2,6,10,14-tetramethyl, Butanoic acid, 3,7-dimethyl-6-octenyl ester, Phthalic acid mono-2-ethylhexyl ester ,, Octanoic acid, heptadecyl ester.


 

Keywords: antimicrobial activity , A.campestris , GC_MS

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Author Biographies

Shatha Ali Shafiq, Department of Biology, College of Science, Mustansiriyah university /Baghdad-Iraq

Department of Biology, College of Science, Mustansiriyah university /Baghdad-Iraq

Rasha Salam Sahib, Al-Rafidain university college –Medical Laboratory Techniques/Baghdad-Iraq

Al-Rafidain university college –Medical Laboratory Techniques/Baghdad-Iraq

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How to Cite
Shafiq, S., & Sahib, R. (2022). Antagonistic Activity of Agaricuscampestris mushroom Extracts Against some Human Pathogenic Bacterial Species. Asian Journal of Pharmaceutical Research and Development, 10(2), 13-16. https://doi.org/https://doi.org/10.22270/ajprd.v10i2.1115