Medicated Lozenges: A Review
Artificial intelligence in drug discovery
A lozenge is a solid dose form of a medicine that is meant to dissolve in the mouth or throat. The creation of lozenges began in the 20th century and is continuing in use now. The advantages of lozenges include an increase in the duration of oral form retention in the oral cavity, which is beneficial. Bioavailability is improved. The difference lowers stomach distress and bypasses the first pass metabolism. Compressed lozenges , hard and soft lozenges are a form of lozenge that is available on the market.n this review there is a method of preparation of lozenges with materials that is required for lozenges are addressed. This review also include the research to date, classification, advantages, disadvantages, formulation evaluation, packaging, storage, uses and parameters of the study
2. Mendes RW, Bhargava H. Lozenges. In:Swarbick J, editor. Encyclopedia of Pharmaceutical Technology. 3rd ed. North California, USA: Informa Healthcare Inc.; 2006:2231-2235.
3. Peters d. Medicated Lozenges. In: LiebermanHA, Lachman L, Schwartz JB, editors. Pharmaceutical dosage forms : Tablets 2nd edition. New York : Marcel Dekker , Inc ; 2005:419 577.
4. Firriolo, JF. Oral cavity- A Review. Oral Surg Med Oral Pathol. 1994; 78(2): 189-93.
5. Batheja, P, Thakur, R, Michniak, B. Basic biopharmaceutics of buccal and sublingual absorption, enhancement in drug delivery. London, New York: Touitou E, Barry BW editors.CRC Press, Taylor and Francis Group. 2006; 1: 189.
6. The Pharmaceutics and compounding Laboratory, Lozenges and medication sticks.Available from: http://pharmlabs.unc.edu/labs/lozenge/lozenges.htm.
7. Maheshwari R., Jain V., Ansari R., Mahajan S.C., joshi G. A Review on lozenges. British Biomedical Bulletin. 2013; 1(1):35-43.
8. Pothu R., Rao Y. Lozenges Formulation and Evaluation. International Journal of Advances in Pharmaceutics. Research. 2014; 5(5):290 – 298.
9. Shinde G., Kadam V., Kapse G.R., Jadhav S.B., Zameeruddin Md., BharkadB.A:Review on lozenges. “Indo American Journal of Pharmaceutical Research. 2014; 4(1):566-571.
10. Darade Ashwini D; medicated lozeges; an udatedreview.”world journal of pharmaceutical science 2021 pg no.118-124”
11. Sohal Taniya , Mahajan Tejaswini, Saxam, Kumar Sunil, Prshar Sonica, MalputraSohit, Bhandari Niraj; Medicated lozenges review’world journal of pharmacy and pharmaceutical sciences, vol-7 2018;pg no 775
12. Pattanayak D, Das S. Formulation development and optimization of medicated Lozengesfor pediatric use. Int J Pharm Sci Res. 2012; 3(1):138-140.
13. Kini R, Rathnanand M, Kamath D. Investigating the suitability of Isomalt and liquid glucose as sugar substitute in the formulation of Salbutamol sulfate hard candy lozenge. J Chem Pharm Res. 2011; 3(4): 69-75
14. H.A. Shojaei. Development of medicated Lozenges. J Pharm Sci. 1998; 1(1):15-30.
15. Rawlins EA. Bentley’s Text Book of Pharmaceutics. 8th ed. Rheology, Bailliere Tindall:London; 1991: 123-139
16. Medicated Lozenges. Marcel Dekker Inc. 2nd Ed. New York and Basel. 1991; I: 339-467.
17. Dineshmohan S, Vanitha K., Ramesh A, Srikanth G, Akila S. Review on medicated Lozenges. Int J Res Pharm Biomed Sci. 2010; 1(2):105-108.
18. Michaud J. Pharmaceutical Confectionary. Pharma Chem Pharmaceu. 2002: 24-27
19. Sastry, SV, Nyshdham JR. Review of formulation used in oral cavity. Pharm Sci and Technol Today. 2000; (3): 138-145.
20. Allen, LV.Troches and Lozenges. Secundum Artem. Current & Practical Compounding Information for the Pharmacist. 2000; 4 (2).
21. Phaemachud, T, Tuntarawongsa, S. Clotrimazol Soft Lozenges Fabricated with Melting and Mold Technique. Res J Pharm Biol Chem
22. Sci. 2010; 1(4): 579-586.
23. Esimone, CO, Okoye, FBC, Odimegwu, DC, Nworu, CS, Oleghe, PO, Ejogha, PW. (2010): In vitro Antimicrobial Evaluation of Lozenges Containing Extract of Garlic and Ginger. Int J Health Res. 3(2): 105-110.
24. Gree,y P, Macdonald, IB.Penicillin Agar Pastilles. CMAJ. 1945; 52(4):327-330.
25. Wade, AG, Morris, C, Shephard, A, Crawford, GM, Goulder, MA. A multicenter randomized, double blind, single-dose study assessing the efficacy of AMC/DCBA Warm lozenge or AMC/DCBA Cool lozenge in the relief of acute sore throat. BMC Fam Pract. 2011;12 (6).
26. Shukla, D, Chakraborty, S, Mishra, B. (2012): Evaluation of vivo behaviour of controlled and pulsatile release pastilles using pharmacokinetic and γ-scintigraphic techniques. Expert Opin Drug Deliv. 9(11):1333-1345.
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