TY - JOUR AU - Chavan, Prajakta J. AU - Vithal J Chawre, Atish B. Velhal. AU - Redasani, Vivek K. PY - 2021/10/15 Y2 - 2024/03/29 TI - Spectrophotometric Evaluation of Antiepileptic Activity of Ficusracemosa in Chemicals Induced Epilepsy in Mice JF - Asian Journal of Pharmaceutical Research and Development JA - Asian J Pharm Res Dev VL - 9 IS - 5 SE - Research Articles DO - 10.22270/ajprd.v9i5.997 UR - https://ajprd.com/index.php/journal/article/view/997 SP - 62-66 AB - <p><strong>Objective: </strong>To Evaluvate of Antiepileptic Acivity of Ficus Racemosa Extract Against Chemicals Induced epilepsy in mice, ficusracemosa is also used as antihyperglycemic, antiinflammatery , hepatoprotective action. <strong>Method : </strong>Anticonvulsant activity of three distinct dose levels of ethanolic extract of Ficus racemosa (100, 200, and 400 mg/kg) was tested in Swiss albino mice in seizures induced by Pentylenetetrazol (PTZ). Statistical analysis was carried out by one-way analysis of variance followed by Dunnett's test. <strong>Results</strong>: The presence of , flavonoids, were detected in the bark of Ficus racemosa. The extract dose-dependent effect in the delay of the onset of seizures and reduction in the duration of seizure.<strong>Conclusion : </strong>The ethanolic extract of Ficus racemosa exhibited significant and dose-dependent antiepileptic activity, which may be due to the presence of antioxidant principles like flavanoidsand other phytoconstituent produce protective activity againstPTZ.</p><p>&nbsp;</p><p>&nbsp;</p> ER -