Potential anti-inflammatory effects of Psidium guajava L.: A review

  • M. Sofyan souri Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147
  • Sri Oktavia Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147
  • Ifora ifora Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147


Inflammation is a defence mechanism of a body against foreign substances. However, Inflammation also plays a key role in diseases such as diabetes, asthma, cardiovascular diseases, and cancer. Increasing scientific evidence has shown that fruits, vegetables, and legumes can have anti-inflammatory properties. This paper aims to provide recent studies on the anti-inflammatory properties of Psidium guajava L. A review was conducted on the studies of Psidium guajava L. anti-inflammatory properties performed during the past 10 years with the literature databases such as Pub Med, Science Direct, Google Scholar. Based on our eligibility criteria, a total of ten studies were included in this paper. The studies suggest that the anti-inflammatory activity of Psidium guajava occurs mainly through inhibition of PGE2, COX-2, NO, iNOS, ERK1/2, leukocyte cell migration, and suppression of edema, paw withdrawal latency as well as exhibited a membrane stabilization effect. This review has demonstrated the importance of Psidium guajava L. as a natural anti-inflammatory potential.


Keywords: Anti-inflammatory, Inflammation, Psidium guajava L.


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Author Biographies

M. Sofyan souri, Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147

Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147

Sri Oktavia, Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147

Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147

Ifora ifora, Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147

Departement of Pharmacology and Clinical Pharmacy, School of Pharmaceutical Science Padang (STIFARM Padang), West Sumatera, Indonesia, 25147


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How to Cite
souri, M., Oktavia, S., & ifora, I. (2021). Potential anti-inflammatory effects of Psidium guajava L.: A review. Asian Journal of Pharmaceutical Research and Development, 9(2), 47-52. https://doi.org/https://doi.org/10.22270/ajprd.v9i2.941