Formulation and Evaluation of Hair Tonic Gel Preparations Resistance Water Fraction N-Hexan Fruit Curm (Phoenix Dactylifera L.)

Authors

  • Chandra P Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
  • Reveny J Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
  • Nainggolan M Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.

DOI:

https://doi.org/10.22270/ajprd.v8i4.772

Keywords:

Dates (Phoenix dactylifera L.), formulations, waterproof gels, hair growth.

Abstract

Objective: This study aims to formulate and evaluate of hair tonicgel preparations resistance water fraction n-hexan fruit curm (Phoenix dactylifera L.)Method: Dates are macerated with 80% ethanol, the extract is concentrated with a rotary evaporator dried with a freeze dryer, the extract is then fractionated with n-hexane. The concentrations used in the preparation of waterproof Hair tonic gel are 5, 7.5, 10 and 12.5% ​​fraction of n-hexane then compared to Hair Tonic from the market. Evaluation of gel preparations includes checking homogeneity, pH, viscosity, irritation, and stability. The animals used are male white rats.Results: The evaluation results of the waterproof gel evaluation on the fraction of n-hexane meet the SNI requirements. Hair tonic waterproof gel preparations yellow to dark brown, homogeneous for 12 weeks of storage at room temperature. The pH and viscosity are stable during 12 weeks of storage and do not irritate the skin. The best hair tonic waterproof hair growth gel growth activity at a concentration of 10%, n-hexane fraction (1.41 ± 0.07).Conclusion: The preparation of waterproof hair tonic gel n-hexane fraction (Phoenix dactylifera L.) has hair growth activity.

Downloads

Download data is not yet available.

Author Biographies

Chandra P, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia

Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia

Reveny J, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia

Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia

Nainggolan M, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.

Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.

References

1. Rostamailis, et al., Tata Kecantikan Rambut: Untuk Sekolah Menengah Kejuruan. Jakarta: Direktorat Pembinaan Sekolah Menengah Kejuruan; 2009.
2. Diana, W dan Wahini M. (2014). Penggunaan Ekstrak Buah Alpukat dan Madu Sebagai Bahan Aktif Hair Tonic Untuk Rambut Rontok. Fakultas Teknik. Universitas Negeri Surabaya. Vol 03(01). Hal 227-232
3. Aini, Q. (2017). Uji Aktivitas Pertumbuhan Rambut Kelinci Jantan dari Sediaan Hair Tonic yang Mengandung Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium L.). Jurnal Farmasi Lampung. Vol 6(2). Hal 2
4. Amer, W.M. and H.A.-R. Ead. History of Botany (part 1): The Date Palm in Ancient History. Taxonomy and documentary study of food plants in Ancient Egypt 1994.Fitriani, E.S.P.(2012). Keajaiban Buah Kurma. (Cetakan Pertama 2012). Yogyakarta: Hal 8-9.
5. Ditjen POM. (1995). Farmakope Indonesia. Edisi IV. Jakarta: Departemen Kesehatan RI. Hal 7.
6. Voight, R. (1994). Buku Pelajaran Teknologi Farmasi. Edisi Kelima. Yogyakarta: Gadjah Mada University Press. Hal 170, 436
7. Strach, M., Dias, T.C.A, Vervier, I., Reeth, I.V., dan Ramos, M.C.T. (2007). Expanding Silicone Tecnologies for Sun Care Performance Complements Aesthetics. Dow Corning Corporation. Hal. 2-7.
8. Ditjen POM. (1979). Farmakope Indonesia. Edisi III. Jakarta: Departemen Kesehatan RI. Hal XXX.
9. Basset, J., Denney, R.C., Jeffrey, G.H.,dan Mendham, J. (1994). Buku Ajar Vogel: Kimia Analisis Kuantitatif Anorganik. Penerjemah : Dr. A. Hadyana Pudjaatmaka dan Ir. L. Setiono. Edisi 4. Jakarta: EGC. 165
10. Jufri, M., Amelia, L., dan Munim, A. (2017). Hair Growth Activity And Safety Test OF Ethosomal Gel Ethyl Acetate Farction Of Nothopanax Leaves (Nothopanax scutellarium Merr.). Asian Journal of Pharmaceutical and Clinical Research. Vol 10(8). Hal 135
11. Caswell, M. (2001). Sunscreen Formulation and Testing. Allured’s Cosmetics and toiletries magazine. Vol 116(9). Hal 52-55.
12. Herdiana, Y. (2007). Formulasi Gel Undesilenil Fenilalanin Dalam Aktifitas Sebagai Pencerah Kulit. Bandung: Fakultas Farmasi Universitas Padjajaran. Hal 7.
13. Margaretha, L. (2015). Formulasi Gel Hair Tonic Ekstrak Kulit Buah Apel (Malus pumila Mill.) dan Uji Aktivitas Pertumbuhan Rambut Marmut. Medan: Skripsi. Fakultas Farmasi. Universitas Sumatera Utara. Hal 22.
14. Barnett G. 1972. Emollient Cream and Lotions. Di dalam Cosmetic Science Technology. Volume I. New York : Willey-Interscience.
15. SNI 16-4955-1998. (1998). Losio Tonik Rambut. Badan Standardisasi Nasional, Jakarta. Hal 1-4.
16. Martin, A., Swarbick, J., dan A. Cammarata. 1993. Farmasi Fisik 2. Edisi III. Jakarta: UI Press. Pp. 940-1010, 1162, 1163, 1170.
17. Garg, A., D. Aggarwal, S. Garg, and A. K. Sigla. 2002. Spreading of Semisolid Formulation: An Update. Pharmaceutical Tecnology. September: 84-102.

Published

2020-08-15

How to Cite

P, C., J, R., & M, N. (2020). Formulation and Evaluation of Hair Tonic Gel Preparations Resistance Water Fraction N-Hexan Fruit Curm (Phoenix Dactylifera L.). Asian Journal of Pharmaceutical Research and Development, 8(4), 4–6. https://doi.org/10.22270/ajprd.v8i4.772