GC-MS Analysis of Methanolic Extract of Colpomenia Sinuosa (Mertens Ex Roth) Derb. Et Sol. From Manapad in the South East Coast of Tamil Nadu, India
Objectives: The present study was carried out to explore the various secondary metabolites and bioactive compounds present in the methanolic extract of brown marine macro alga Colpomenia sinuosa (Mertens Ex Roth) Derb. Et Sol.
Design: The plant materials were collected from Hare Island, located in Thoothukudi, Tamil Nadu, India. The characterization of biochemicals was carried out using GC-MS analysis.
Intervention: Among the different solvent extracts, methanolic extract was intervened in the present study
Main outcome measure: The main measurement results in the study were to predict the presence of various phytochemicals in the methanolic extract of Colpomenia sinuosa (Mertens Ex Roth) Derb. Et Sol.
Results: The analysis revealed seventeen bioactive compounds such as z,z-6,28-Heptatriactontadien-2-one (25.88%), 2-Hexadecanol (2.18%), L-(+)-Ascorbic acid (25.13%), N-propyl 11-octadecenoate (9.41%), 3-Methyl-2-(2-oxopropyl)furan (2.02%), Hexadecane (1.01%), Hentriacontane (9.00%), Palmitaldehyde (4.22%), Tritetracontane (2.42%), Squalene (1.03%), Trans-5-Hexyl-1,4-dioxane-2-carboxylic acid (4.12%), Methyl 2-hydroxy-eicosanoate (3.25%), Cyclopentane,1,1,3-trimethyl- (2.15%), Palmitoleic acid (1.64%), Vitamin E (0.18%), 2-Pentacosanone (0.22%) and 3-Methylene-1-oxa-spiro[3,6]decane (0.14%).
Conclusion: The bioactive compounds from methanolic extract of Colpomenia sinuosa (Mertens Ex Roth) Derb. Et Sol. may have the potential effect against various diseases.
2. Iliopoulere D, Agias C, Harvala C, Roussis V. C15 acetogenins from the red alga Laurencia obtusa. Phytochemistry. 2002; 59:111-6.
3. Metzger P, Roger MN, Largean C. Botryolins A & B, two tetramethyl sequalene triethers from the green microalga Botryoccus braunic. Phytochemistry. 2002; 59:839-43.
4. Lekameera R, Vijayabaskar P, Somasundaram ST. Potential antioxidant activity of brown alga Lobophora variegate. Seaweed Res. Utiln. 2007; 29(1&2):55-61.
5. Lekameera R, Vijayabaskar P, Somasundaram ST. Evaluating antioxidant property of brown alga Colpomenia sinuosa (Derb. Et sol). African J. Food Sci. 2008; 2:126-30.
6. Fayaz K, Namitha KN, Chidambara MM, Mahadeva SR, Sarada SK, Ravishankar S. Chemical composition Iron bioavailability and antioxidant activity of Kappaphycus alvarezi (Doty). J. Agric. Food Chem. 2005; 53:792-7.
7. Thirumaran G, Vijayabaskar P, Anantharaman P. Antibacterial and antifungal activities of brown Marine macro algae (Dictyota dichotoma) from the Gulf of mannar biosphere reserve. Environ. Ecol. 2006; 24S(1):37-40.
8. Oh, Kim, Lee. Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. Bioorganic and Medicinal Chem. Lett. 2008; 18:104-8.
9. Venkateswarlu G, Panchagnula K, Aditya L, Gottumukkala VS. Synthesis, structural revision and biological activities of 4-chloroaurone, a metabolite of marine brown alga Spatoglossum variabile. Tetrahedron. 2007; 63:6909-14.
10. Yang L, Peng LS, Zhou S. Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. Bioorganic and Med. Chem. Lett. 2006; 16:4205-8.
11. John Peter Paul J, Sakunthala M. Preliminary phytochemical analysis of Ctenolepis garcinii (Burm. F.) C.B. Clarke. International Journal of Pharmacy Practice & Drug Research. 2017; 7(1):4-7.
12. John Peter Paul J. Phytochemical studies on Turbinaria ornata (Turner) J.Ag. American Journal of PharmTech Research. 2012; 2(6):1-8.
13. John Peter Paul J. GC-MS analysis of acetone extract of Caulerpa racemosa (Forssk.) Web. V. Bosse collected from Kanyakumari in the south east coast of Tamil Nadu, India. Journal of Drug Delivery & Therapeutics. 2019; 9(4):571-3.
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