Literature Review on the Biological Effects of Taraxacum Officinale Plant In Therapy
DOI:
https://doi.org/10.22270/ajprd.v7i3.502Keywords:
Phytotherapy. Taraxacum officinale. Antioxidants. Properties anticancer action.Abstract
Since human beings have sought in nature, components that can obtain help in therapeutics or even in the cure of diseases. The progress made in the area of science promoted the development of recognized and effective herbal medicines, as well as the search for the population, for less aggressive treatments. The evaluation of the antioxidant activity of plants has been an important issue taking into account its importance on human health, since the natural antioxidants present a reduced health risk, when compared to the synthetic ones that present toxic effect. From the Asteraceae family, of which the plant species Taraxacum officinale, popularly known as dandelion, stands out among the 71 species on the list of the Ministry of Health (RENISUS), scientifically affirmed, to treat liver disorders, inflammations, potential in the anti-bacterial, cytotoxic, antiviral, antiparasitic, antifungal activity, besides studies to verify its anticancer action and of carcinogenic prevention. The acute toxicity of Taraxacum officinale appears to be low, with LD50 values estimated at 36.8g / kg and 28.8g / kg, for the whole plant. The adverse or complex toxic effects for T. officinale have not yet been reported. This review of the literature was elaborated through studies of articles contained in the Scielo, Google Scholar and Pub Med platforms. Through this review the importance of phytotherapy studies for pharmacological purposes was verified, aiming to improve the therapeutics.
Downloads
References
2. Silva E J, Nascimento CCHC, Nascimento SF, Vasconcelos SDDDe, Nogueira RI, Stephens PRS, Barreto AS And Diré GF, Study of The Biological Effects of Aqueous Extracts of Schinus terebinthifolius raddi, on the Survival Fraction of Mutant and Wild Strains of Escherichia Coli. Merit Research Journals.2018; 6:89
3. Guerra M P, Nodari RO, Biodiversidade Aspectos Biológicos, Geográficos, Legais E Éticos. In: Simões, CMO, Schenkel EP, Gosmann G, Mello JCP, Mentz LA, Petrovick PR (Ed.). Farmacognosia: Da Planta Ao Medicamento. 6. Ed. Porto Alegre: Editora Da Ufrgs.2007; 4-28.
4. Bila DM, Dezotti M. Fármacos No Meio Ambiente. Quím. Nova, São Paulo.2003; 26(4):523-530.
5. Leite Nadghia F. Sobral-Souza CE, Albuquerque RS, Brito DI, Lavor AK, Alencar LB. Cunha FA. Actividadantiparasitaria In Vitro Citotóxica De Cariofileno Y Eugenol Contra Trypanosoma Cruzi Y Leishmania Brasiliensis. Revista Cubana De Plantas Medicinales. 2013; 18(4): 522-528.
6. Lorenzi H, Matos FJA, Plantas Medicinais No Brasil: Nativas E Exóticas. Novaodessa, Sp: Instituto Plantarum, 2002. 512 P
7. Velázquez, E Et Al. Antioxidant Activity of Paraguayan Plant Extracts. Fitoterapia. 2003; 74(1-2):91-97.
8. Cowan MM. Plant Products As Antimicrobial Agents. Clin. Microbiol. Rev, 1999; 12(4):564-582.
9. Ahmad VU, Yasmeen S, Ali Z, Khan MA, Choudhary MI, Akhtar F, Miana GA, Zahid M, Taraxacum A New Guaianolide From Taraxacum wallichii. Journal of Natural Product. 2000; 63:1010–1011.
10. Brasil, Ministério Da Saúde; Portal Da Saúde. Plantas De Interesse Ao Sus. 2014.
11. Cronquist AF. Farmacognosia.4.Ed.Lisboa: Fundação Caloustegulbenkian.1979; 2:1010.
12. Teske M, Trentini AMM, Compêndio De Fitoterapia .3 edition . Curitiba: Herbarium.1997. P.120-121.
13. Kissmann KG, Groth D, Plantas Infestantes E Nocivas. São Paulo: Basf Brasileira, Tomo Ii.1992; P. 798.
14. Costa AF. Farmacognosia. 4ed. Lisboa: Fundação Caloustegulbenkian.1979; 2:1010.
15. Panizza, S. Plantas Que Curam (Cheiro De Mato). 16.Ed. São Paulo: Ibrasa.1996; 279p.
16. Lorenzi H; Matos FJA . Plantas Daninhas Do Brasil: Terrestres, Aquaticas, Parasitas, Toxicas E Medicinais. 2.Ed. Nova Odessa: Plantarum. 1991; 440p.
17. Alonso JR, Tratado De Fitomedicina, Bases Clínicas E Farmacológicas. Buenos Aires: Ediciones Srl.2000; 743p.
18. Nascimento JE, Melo AFM, Lima E Silva TC, Veras Filho J, Santos EM, Albuquerque UP, Amorim ELC, Estudo Fitoquímico E Bioensaio Toxicológico Frente A Larvas De Artemia Salina Leach. De Três Espécies Medicinais Do Gênero Phyllanthus (Phyllanthaceae). Journal of Basic and Applied Pharmaceutical Sciences.2008; 29(2):143-148.
19. Newall Ca, Anderson, La, Phillipson, Jd, Plantas Medicinas: Guia Para Profissional De Saúde. Ed. Premier.2002.
20. Fabri RL, Nogueira MS, Dutra LB, Bouzada MLM, Scio E. Potencial Antioxidante E Antimicrobiano De Espécies Da Família Asteraceae. Revista Brasileira De Plantas Medicinais.2011; 13(2):183-189.
21. Dariuszjedrejek, Bernadetta Lis, Agatarolnik, Anna Stochmal, Beata Olas. Comparative Phytochemical, Cytotoxicity, Antioxidant and Haemostatic Studies of Taraxacum officinale Root Preparations. Revista Acceptedmanuscript. 2019.
22. Michałmiłek, Dana MarcinˇCáková and Jaroslav Legáth. Polyphenols Content, Antioxidant Activity, And Cytotoxicity Assessment of Taraxacum officinale Extracts Prepared Through The Micelle-Mediated Extraction Method. Revista Molecules;2019.
23. Seo,SW, Koo HN, An HJ, Kwon KB, Lim BC, Seo EA, Ryu DG, Moon G, Kim HY, Kim HM, Hong SH, 2005. Taraxacum officinale Protects Against Cholecystokinin-Induced Acute Pancreatitis In Rats. World Journal of Gastroenterology.2005; 11:597–599.
24. Koo HN, Hong SH, Song BK, Kim CH, Yoo YH, Kim HM, Taraxacum officinale Induces Cytotoxicity Through Tnf- And Il-1 Secretion In Hepg2 Cells. Life Sciences.2004; 74:1149–1157.
25. Kim HM, Oh CH, Chung CK, Activation of Inducible Nitric Oxide Synthase By Taraxacum officinale In Mouse Peritoneal Macrophages. General Pharmacology.1999; 32:683–688.
26. Zhu M, Wong P.Y, Li RC, Effects of Taraxacum mongolicum on The Bioavailability and Disposition of Ciprofloxacin In Rats. Journal of Pharmaceuticalsciences.1999; 88:632–634.
27. Takasaki M, Konoshima T, Tokuda H, Masuda K, Arai Y, Shiojima K, Ageta H, Anti-Carcinogenic Activity of Taraxacum Plant. Biological and Pharmaceutical Bulletin.1999; 22:602–605.
28. Sophia C. Sigstedt, Carla J. Hooten, Manika C. Callewaert, Aaron R. Jenkins, Anntherese E. Romero, Michael J. Pullin, Alexander Kornienko, Timothy K. Lowrey, Severine Van Slambrouck and Wim F.A. Steelant. Evaluation of Aqueous Extracts of Taraxacum officinale On Growth and Invasion of Breast And Prostate Cancer Cells. International Journal of Oncology.2008; 32:2008.
29. Cunha A, Teixeira, Frederico; Silva, Alda; Roque, Odete. Plantas Naterapêutica Farmacologia E Ensaios Clínicos. Fundação Caloustegulbenkian. 2010; 360-380.
30. Head, Kathleen. Natural Approaches to Prevention and Treatment of Infections of the Lower Urinary Tract. Alternative Medicine Review.2008; 13(3): 223-235.
31. Hisano Marcelo, Bruschini Homero, Nicodemo Antonio Carlos, Srougi Miguel. Cranberries and Lower Urinary Tract Infection Prevention. Clinics. 2012; 661-665.
32. Cowan C, Hutchison C, Cole T, Barry S, Paul J, Reed N, Russell JA, Randomised Double-Blind Placebo-Controlled Trial To Determine The Effect of Cranberry Juice on Decreasing The Incidence of Urinary Symptoms And Urinary Tract Infections In Patients Undergoing Radiotherapy For Cancer of The Bladder Or Cervix. Clinical Oncology. 2012. E31.
33. Nowack Rainer, Schmitt Wilhelm, Cranberry Juice for Prophylaxis of Urinary Tract Infections – Conclusions from Clinical Experience and Research. Phytomedicine.2008; 15:653-663.
34. Cunha A, Roque Odete. Plantas Medicinais Da Farmacopeia Portuguesa – Constituintes, Controlo, Farmacologia E Utilização. Fundação Caloustegulbenkian.A Edição. Revista E Atualizada.2011; 203- 678.
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.