SCREENING PHYTOCHEMICAL AND ANTI-METHICILLIN RESISTANT (MRSA) ACTIVITY OF 70 % ETHANOLIC EXTRACT FROM THE STEM BARK OF ALBIZIA LEBBECK(L.) BENTH.(FABACEAE)

  • Yao KANGA Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.
  • CAMARA Djeneb Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.
  • KOUASSI Kouadio Aubin Training and Research Unit Sciences of the nature,Nangui Abrogoua University (Ivory Coast), 02 BP 801Abidjan 02.
  • ZIRIHI Guédé Noël Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

Abstract

The emergence of multi-drug resistant strains and limitations of present antimicrobial drugs have led to continuous search for natural products as curative agents for Anti-methicillin resistantinfections. The aim of this study was to evaluate antibacterial activity of an ethanolic extract from Albizia lebbeckstem bark against Anti-methicillin resistant. Methods and Results : The methods of dissemination swab on muller-hinton agar and double dilution were used to evaluate the antibacterial activity of 70 % ethanolic extract of stem bark of Albizia lebbeck.All multi-resistant strains of Staphylococcus aureus and the reference strain (ATCC 25923) were sensitive to 70 % ethanolic extract of the stem bark of Albizia lebbeck. The MBCvary from 0,49 mg/mL to 2mg/mL. Also, the phytochemical screening of this extract revealed the presence of  Polyphenols, Gallic tannins, Catechin tanninsand Flavonoids. These findings confirm that an 70 % ethanolic extract from Albizia lebbeck stem bark inhibited growth of Anti-methicillin resistant at low concentration and could be utilised as an alternative Anti-methicillin resistantagent.

Keywords: Albizia lebbeck, Anti-methicillin resistant, 70 % ethanolic extract, MBC

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Author Biographies

Yao KANGA, Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

CAMARA Djeneb, Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

KOUASSI Kouadio Aubin, Training and Research Unit Sciences of the nature,Nangui Abrogoua University (Ivory Coast), 02 BP 801Abidjan 02.

Training and Research Unit Sciences of the nature,Nangui Abrogoua University (Ivory Coast), 02 BP 801Abidjan 02.

ZIRIHI Guédé Noël, Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

Botany Laboratory, Training and Research Unit Biosciences, 22 BP 582 Abidjan 22, Felix Houphouet-Boigny University, Ivory Coast.

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KANGA, Y., Djeneb, C., Aubin, K., & Noël, Z. (2018). SCREENING PHYTOCHEMICAL AND ANTI-METHICILLIN RESISTANT (MRSA) ACTIVITY OF 70 % ETHANOLIC EXTRACT FROM THE STEM BARK OF ALBIZIA LEBBECK(L.) BENTH.(FABACEAE). Asian Journal of Pharmaceutical Research and Development, 6(6), 1-6. https://doi.org/https://doi.org/10.22270/ajprd.v6i6.458