BIOLOGICAL EVALUATION OF SAUSSUREA LAPPA ROOT EXTRACT FOR ANALGESIC AND ANTI- INFLAMMATORY ACTIVITY

Authors

  • Juluri Krishna Dutta Tejaswi Department of Pharmaceutical Chemistry, Hindu College of Pharmacy, Amaravathi Road, Guntur (AP), India
  • R. Govinda Rajan Department of Pharmaceutical Chemistry, Hindu College of Pharmacy, Amaravathi Road, Guntur (AP), India
  • P Sara Department of Pharmaceutical Chemistry, Hindu College of Pharmacy, Amaravathi Road, Guntur (AP), India

DOI:

https://doi.org/10.22270/ajprd.v6i4.378

Keywords:

Saussurea lappa, Ethonolic, Glycosides, Analgesic, Anti-inflammatory

Abstract

The present study was designed to evaluate the Phytochemical Screening for Analgesic and Anti- inflammatory activities of Ethonolic extract of Saussurea lappa.  The collected plant root material were washed, shade dried, and size reduced into small pieces. Dried materials were coarsely powdered and macerated with petroleum ether for 72 hrs. The plant material was extracted by using ethanol by the cold maceration method. The study concluded that the root extract have potential bioactive substances that may be used to formulate new drugs. The Flavo-Glycosides content in Ethonolic extract of Saussurea lappa root was extracted and results were compared with the standard for Analgesic and Anti- inflammatory activities. The results were compared with the standard using statistical method. However further investigation was required for structural elucidation and pharmacological properties.

Keywords: Saussurea lappa, Ethonolic, Glycosides, Analgesic, Anti-inflammatory.

Downloads

Download data is not yet available.

References

1. Mohammad Asim Khan. Qust (Saussurea Lappa Clarke.) - A Potent Herb of Unani Medicine: A Review. Int J of Cur Pharm Res, 2013; 5 (4): 213-219.
2. Kolisetty Sambasiva Rao. Acylated Flavones Glycosides from the roots of Saussurea lappa and their Antifungal Activity. Molecules, 2007; 12: 328-344.
3. Bose. Some aspects of phytochemical and pharmacological study of Saussurea lappa. J of Pharm Sci, 1961, 50: 679–681.
4. Kretschmer N. Activity Guided Isolation of Anti-Tumour Compounds from Saussurea lappa Clarke. Sci Pharm, 2009; 77: 246-251.
5. Uma Chandur. Phytochemical Evaluation and Anti-Arthritic Activity of Root of Saussurea lappa. Pharmacologia, 2011; 2: 265-269.
6. Thara K M. Comprehensive In-vitro pharmacological activities of different extracts of Saussurea lappa. J of Exp Bio, 2012; 2 (2):417-420.
7. Madan Mohan Pandey. Saussurea costus botanical, chemical and pharmacological review of an ayurvedic medicinal plant. J of Ethno Pharm, 2007; 110: 379–390.
8. Cho. Inhibitory effect of Sesquiterpenes lactones from Saussurea lappa on tumor necrosis factor-alpha production in murine macrophage like cells. Planta Medica, 1998; 64: 594–597.
9. Ravi Shankar Pandey. Saussurea lappa extract modulates cell mediated and humoral immune response in mice. Der Pharmacia Lettre, 2012; 4 (6): 1868-1873.
10. P Upadhyay. Study of Kustha (Saussurea Lappa, Clarke) in ischemic Heart Disease Ancient. Sci of Life, 1993; 13(1):11-18.
11. Anbu J. Evaluation of antihyperlipidemic Activity of Ethanolic Extract of Saussurea Lappa in rats. Int J of Pharm and Bio Sci, 2011, 2:147-154.
12. Niranjan Sutar. Antiulcerogenic Activity of Saussurea Lappa Root. Int J of Pharm & Life Sci, 2011; 2(1):210-217.
13. Juluri Krishna Dutta Tejaswi. Investigation of phytochemical activities of Saussurea Lappa C.B. clarke root extract. World J Pharm Sci, 2018; 6(8).

Published

2018-08-23

How to Cite

Tejaswi, J. K. D., Rajan, R. G., & Sara, P. (2018). BIOLOGICAL EVALUATION OF SAUSSUREA LAPPA ROOT EXTRACT FOR ANALGESIC AND ANTI- INFLAMMATORY ACTIVITY. Asian Journal of Pharmaceutical Research and Development, 6(4), 35–38. https://doi.org/10.22270/ajprd.v6i4.378