Formulation Evaluation and Comparative Study of Herbal Mouthwash with Marketed Preparation

Authors

  • Aman Mohata Kamla Nehru College of Pharmacy Butibori, Nagpur, Maharashtra (India)-441122
  • Seema Wakodkar Kamla Nehru College of Pharmacy Butibori, Nagpur, Maharashtra (India)-441122
  • Jagdish Baheti Kamla Nehru College of Pharmacy Butibori, Nagpur Maharashtra (India)- 441108

DOI:

https://doi.org/10.22270/ajprd.v12i6.1501

Abstract

The current study aims to create and assess a herbal mouthwash and assess its efficacy in combating the oral cavity's microbial load. To extract the hydroalcoholic and water-soluble components, plant materials were gathered. Piper nigrum seeds and hibiscus flowers were used to prepare herbal mouthwash for extraction. The prepared mouthwash's pH, antibacterial activity, and physicochemical characteristics were further assessed. The mouthwash that is currently available has good antibacterial qualities. Currently, available mouthwash is a liquid formulation that often includes antiseptic and antibacterial ingredients. The major benefits of utilizing mouthwashes are that they can be used regularly at home to maintain good oral hygiene, that they have antibacterial activity, that they can be used as prophylaxis before and after oral surgery procedures like tooth extractions, and that they clean teeth after brushing. These solutions may be used for various purposes, such as their analgesic, anti-inflammatory, or anti-fungal properties, in addition to their ability to lessen microbial development, gingivitis, and halitosis in the oral cavity.

 

Downloads

Download data is not yet available.

Author Biographies

Aman Mohata, Kamla Nehru College of Pharmacy Butibori, Nagpur, Maharashtra (India)-441122

Kamla Nehru College of Pharmacy Butibori, Nagpur, Maharashtra (India)-441122

Seema Wakodkar, Kamla Nehru College of Pharmacy Butibori, Nagpur, Maharashtra (India)-441122

Kamla Nehru College of Pharmacy Butibori, Nagpur, Maharashtra (India)-441122

Jagdish Baheti, Kamla Nehru College of Pharmacy Butibori, Nagpur Maharashtra (India)- 441108

Kamla Nehru College of Pharmacy Butibori, Nagpur Maharashtra (India)- 441108

References

Sandhya R. Herbal products as mouthwash–a review. Int J Sci Res. 2017 Jul; 6(7):1334-7.

Beltrami M, Bickel M, Baehni PC. The effect of supragingival plaque control on the composition of the subgingival microflora in human periodontitis. Journal of Clinical Periodontology. 1987 Mar;14(3):161-4.

Abdeia RF. The periodontal condition of the elderly in a developed and developing country. The University of Manchester (United Kingdom); 1997.

Porter SR, Scully C. Oral malodour (halitosis). Bmj. 2006 Sep 21; 333(7569):632-5.

Ileri Keceli T, Gulmez D, Dolgun A, Tekcicek M. The relationship between tongue brushing and halitosis in children: a randomized controlled trial. Oral diseases. 2015 Jan; 21(1):66-73.

Nigam D, Verma P, Chhajed M. Formulation and evaluation of herbal mouthwash against oral infections disease. Int J Pharm Life Sci. 2020 Jul 1;11(7):6746-50.

Al-Snafi AE. Chemical constituents, pharmacological effects and therapeutic importance of Hibiscus rosa-sinensis-A review. IOSR Journal of Pharmacy. 2018;8(7):101-19.

Shandilya S, Pathak V. Chemical constituents & pharmacological effects of Hibiscus rosa-sinensis (china rose)–a review. World Journal of Pharmaceutical Research. 2020 Nov 11;10(1):858-69.

Gupta PC, Sharma N. 8 An Overview of Traditional. Aquatic Medicinal Plants. 2023 Aug 1:121.

Varoni E, Tarce M, Lodi G, Carrassi A. Chlorhexidine (CHX) in dentistry: state of the art. Minerva Stomatol. 2012 Sep 1;61(9):399-419.

Damanhouri ZA, Ahmad A. A review on therapeutic potential of Piper nigrum L. Black Pepper): The King of Spices. Med. Aromat. Plants. 2014;3(3):161.

Vishvnath Gupta VG, Jain UK. Status of piperine content in Ayurvedic formulation: method standardization by HPTLC.

Shingate PN, Dongre PP, Kannur DM. New method development for extraction and isolation of piperine from black pepper. International Journal of Pharmaceutical Sciences and Research. 2013 Aug 1;4(8):3165.

Nigam D, Verma P, Chhajed M. Formulation and evaluation of herbal mouthwash against oral infections disease. Int J Pharm Life Sci. 2020 Jul 1;11(7):6746-50.

Hidalgo E, Dominguez C. Mechanisms underlying chlorhexidine-induced cytotoxicity. Toxicology in vitro. 2001 Aug 1;15(4-5):271-6.

Varoni E, Tarce M, Lodi G, Carrassi A. Chlorhexidine (CHX) in dentistry: state of the art. Minerva Stomatol. 2012 Sep 1;61(9):399-419.

Puig Silla M, Almerich Silla JM. Use of chlorhexidine varnishes in preventing and treating periodontal disease. A review of the literature. Med. oral patol. oral cir. bucal (Internet). 2008:257-60.

Lorenz K, Bruhn G, Heumann C, Netuschil L, Brecx M, Hoffmann T. Effect of two new chlorhexidine mouthrinses on the development of dental plaque, gingivitis, and discolouration. A randomized, investigator‐blind, placebo‐controlled, 3‐week experimental gingivitis study. Journal of clinical periodontology. 2006 Aug;33(8):561-7.

Ribeiro LG, Hashizume LN, Maltz M. The effect of different formulations of chlorhexidine in reducing levels of mutans streptococci in the oral cavity: A systematic review of the literature. Journal of dentistry. 2007 May 1;35(5):359-70.

Shingate PN, Dongre PP, Kannur DM. New method development for extraction and isolation of piperine from black pepper. International Journal of Pharmaceutical Sciences and Research. 2013 Aug 1; 4(8):3165.

Nigam D, Verma P, Chhajed M. Formulation and evaluation of herbal mouthwash against oral infections disease. Int J Pharm Life Sci. 2020 Jul 1; 11(7):6746-50.

Published

2024-12-15

How to Cite

Aman Mohata, Seema Wakodkar, & Jagdish Baheti. (2024). Formulation Evaluation and Comparative Study of Herbal Mouthwash with Marketed Preparation. Asian Journal of Pharmaceutical Research and Development, 12(6), 140–146. https://doi.org/10.22270/ajprd.v12i6.1501

Most read articles by the same author(s)