A Prospective Observational Study to Assess Rationality and Drug Characterisation in the Prescription of Opioids in Post-Operative Patients in A Tertiary Care Hospital
DOI:
https://doi.org/10.22270/ajprd.v13i1.1498Abstract
Opioid are the narcotic analgesics which are routinely prescribed for postoperative pain management.The CDC developed guidelines for prescribing opioids to ensure safe, effective care and reduce opioid-related issues in chronic pain management.
This prospective observational study focused on assessment of rationality opioid in the prescription and drug characterization of opioid among post operative patients in a tertiary care hospital for a period of 6 months. The data was collected using information provided by patient medical record, CDC guidelines were used to assess rationality. Rationality in the opioid prescription was assessed using CDC guideline and revealed that majority of the opioid prescription were rational. High degree of irrationality was observed with Inj.Tramadol and long duration opioid prescription, emphasizing the importance of implementation of CDC guidelines.
Opioid drug characterization study revealed that majority of the patients were prescribed with Tab. Tramadol during hospitalization and discharge followed by inj. Tramadol, buprenorphine, morphine. In addition, some of the patients prescribed with buprenorphine at discharge possibly indicating leading to the misuse of the opioid.
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Bohnert AS, Guy Jr GP, Losby JL. Opioid prescribing in the United States before and after the centers for disease control and prevention’s 2016 opioid guideline. Annals of internal medicine. 2018; 169(6):367-75.
Ladha KS, Neuman MD, Broms G, Bethell J, Bateman BT, et al. Opioid prescribing after surgery in the United States, Canada, and Sweden. JAMA Network Open. 2019;2(9):1-11.
Clarke H, Soneli N, Ko D T, Yun L, Wijeysundera D N. Rates and risk factors for prolonged opioid use after major surgery: population-based cohort study. BMJ. 2014; 348:1-10.
Chen D, Li X, Chen Y, Zeng H, Liu J, Li Q. Opioid Dose, Pain, and Recovery following Abdominal Surgery: A Retrospective Cohort Study. Journal of Clinical Medicine. 2022 ;11(24):1-14.
Sabatino JM, Kunkel TS, Ramkumar BD, Keeney JB, Jevsevar SD. Excess Opioid Medication and Variation in Prescribing Patterns Following Common Orthopedic Procedures. The journal of bone& joint surgery. 2018 ;100(3): 180-188.
Joshi S, Shetty Y, Panchal R, Patankar P, Salgaonkar S, Rawat R. An observational study to evaluate the prescription pattern of analgesics used in the perioperative period in a tertiary care hospital. Perspectives in Clinical Research. 2021;12(3):165.
Skala K, Reichl L, Ilias W, Likar R, Grogl-Aringer G, Wallner C, et al. Can we predict addiction to opioid analgesics? A possible tool to estimate the risk of opioid addiction in patients with pain. Pain physician. 2013;16(6):593
McElyea J, Sam B, Hollingsworth H, Chamberlain C, Brown LS. The Effect of Patient Opioid Education on Opioid Use, Storage, and Disposal Patterns. Journal of Pain & Palliative Care Pharmacotherapy. 2022;36(1):11-17.
Bartels K, Mayes LM, Dingmann C, Bullard KJ, Hopfer CJ, Binswanger IA. Opioid Use and Storage Patterns by Patients after Hospital Discharge following Surgery. PLoS One. 2016;11(1):1-10.
Manchikanti L, Giordano J, Boswell MV, Fellows B, Rajeev Manchukonda BD, Pampati V. Psychological factors as predictors of opioid abuse and illicit drug use in chronic pain patients. Journal of opioid management. 2007 Mar 1;3(2):89-100.
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