A Review on Moringa Olifera Effervescent Tablet
DOI:
https://doi.org/10.22270/ajprd.v12i6.1489Abstract
The D-optimal mix design was utilized in the new product development process of the Moringa oleifera effervescent tablet to optimize the acid-base ratio in the recipe. The antioxidant activity and chemical profile of the Moringa oleifera extract were assessed. Measurements were made on the physicochemical and sensory properties of the effervescent Moringa oleifera tablet. Because moringa leaves, which are a component of the Moringa Oleifera plant, have a high antioxidant content, they help the body fight off free radicals. Additionally, the contents of the leaves may be turned into effervescent granules, a functional drink. The kind and proportion of the effervescent agent have a significant impact on the granule's physical properties, stability, and acceptability. Because they both offer a texture and mouthfeel that is acceptable, sodium bicarbonate and citric acid were employed as the effervescent agents in this investigation. Three formulations (designated as F1, F2, and F3) with varying ratios of citric acid to sodium bicarbonate were chosen. The wet granulation process was used to create these formulations. The three formulations' effervescent granules demonstrated good particle size distribution and flow capabilities. Furthermore, an extract from Moringa oleifera displayed IC50 values of 320µg/ml. Acceptability-wise, all of the recipes had a somewhat bitter taste, which could be attributed to the extract's tannins and phenolic components. Addition of flavoring agents, such as lemon and strawberry, is unable to mask the bitter taste of the final tablet. Here in, the first Moringa leaves effervescent tablet prepared using wet granulation was successfully formulated.
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References
Divya K, Vamshi G, Vijaykumar T, Sandhya Rani M and Kishore B: Review on Introduction to Effervescent Tablets and Granules. Kenkyu Journal of Pharmacology 2020; 6: 01-11
Ali, Muhammad Azhar, Yusof YA, Chin NL and Ibrahim MN: Development and standardization of Moringa oleifera leaves as a natural dietary supplement. Journal of Dietary Supplements 2018; 1: 1–20
Hirani JJ, Rathod DA, and Vadalia KR, Orally disintegrating tablets: A review. Trop J Pharm Res, 2009. 8(2): 161-172.
Patel, Salim & Siddaiah, M. (2018). Formulation and evaluation of effervescent tablets: a review. Journal of Drug Delivery and Therapeutics. 8. 296-303. 10.22270/jddt.v8i6.2021.
Eoin GM, Nicolas ER and Mark AF: Powder and Reconstituted Properties of Commercial Infant and Follow-On Formulas. Foods 2020; 9(1): 84.
Elena G, Isabel U, Marta S and Pilar GS: Nutritional Value of Moringa oleifera Lam. Leaf Powder Extracts and Their Neuroprotective Effects via Antioxidative and Mitochondrial Regulation. Nutrients 2021; 13(7): 2203.2.
Lenin S, Sujatha R and Sundaram S: Nutritional Composition, Mineral analysis and Sensory Evaluation of Cake and Chocolate with Moringa oleifera Leaf Powder. Journal of Pharmaceutical Research International 2021; 33(60): 2367–2373
Hilda M, Irma S, Meutia F and Kevin K: Formulation of Effervescent Granule from Robusta Green Coffee Bean Ethanolic Extract (Coffea canephora). J Pharm Bioallied Sci 2020; 12(2): 743-746
Murdiana, Happy & Revika, Era & Rahmawati, Dewi & Puspitasari, Tetty & Darumas Putri, Athika & Tri Murti, Bayu. (2018). Moringa oleifera Lam.-Based Effervescent Tablets: Design, Formulation and Physicochemical Evaluation. 10.25258/ijddt.v8i4.9.
Hilda M, Irma S, Meutia F and Kevin K: Formulation of Effervescent Granule from Robusta Green Coffee Bean Ethanolic Extract (Coffea canephora). J Pharm Bioallied Sci 2020; 12(2): 743-746
Asare, G.A.; Gyan, B.; Bugyei, K., Adjei, S.A., Mahama, R.; Addo, P., Out-Nyarko,L.,Wiredu,E.K.andNyarko, A.Toxicitypotentialsof thenutraceuticalMoringaoleiferaAt supra-supplementationlevels. Journal of Ethnopharmacology2012; 139 265-272.
Mutahar, R. K. M., Nagesh, C., Ramesh, R., & Omer, S. (2008). Formulation , development and in vitro evaluation of effervescent tablets of niacin for dyslipidemia. 1(1), 107–114 Nambiar, V. S., & Parnami, S. (2008). Standardization and organoleptic evaluation of drumstick ( Moringa oleifera ) leaves incorporated into traditional indian recipes. Trees for Life Journal, 3(9), 2–6. https://doi.org/10.1111/j.1750-3841.2010.01990.
x Noval, N., Rosyifa, R., & Annisa, A. (2020). Effect of HPMC concentration variation as gelling agent on physical stability of formulation gel ethanol extract bundung plants (Actinuscirpus Grossus). Proceedings of the First National Seminar Universitas Sari Mulia, 1-15. https://doi.org/10.4108/eai.23-11-2019.2298326
Okoye, E. I., Awotunde, T. O., & Morales, T. G. (2013). Formulation and characterization of Moringa oleifera leaf granules. I: Micromeritic properties. Research Journal of Pharmacy and Technology, 6(1), 66–74
Olabode, Z., Akanbi, C. T., Olunlade, B., & Adeola, A. A. (2015). Effects of drying temperature on the nutrients of Moringa (Moringa oleifera). Direct Research Journal of Agricultural and Food Science (DRJAFS), 3(5), 117–122
Pandey, P., Sharma, P., Gupta, R., Garg, A., Shukla, A., Nema, N., & Pasi, A. (2013). Formulation and evaluation of herbal effervescent granules incorporated with martynia annua extract. Journal of Drug Discovery and Therapeutics, 1(5), 54–57 Rahmawati, P. S., & Adi, A. C. (2017).
Daya terima dan zat gizi permen jeli dengan penambahan bubuk daun kelor (Moringa Oleifera). Media Gizi Indonesia, 11(1), 86. https://doi.org/10.20473/mgi.v11i1.86-93
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