Kartagener Syndrome: A Case Report

Authors

  • Dr Anuradha Kapoor AJPRD Senior Resident, General Medicine Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi
  • Dr Mitva Agarwal Senior Resident, ENT Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi
  • Dr Kanika Maheshwari Senior Resident, Pathology Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

DOI:

https://doi.org/10.22270/ajprd.v12i6.1459

Abstract

Kartagener syndrome is a rare, autosomal recessive genetic disorder that causes defects in the action of ciliary movement, characterized by clinical triad of situs inversus, chronic sinusitis, and bronchiectasis. We present the case of an 18-year-old male with repeated respiratory infections. He was diagnosed with Kartagener syndrome based on his clinical presentation and imaging features. In patients presenting with recurrent upper and lower respiratory tract infections, Kartagener syndrome should always be kept in mind. The correct diagnosis of this disorder in early life is very important to prevent complications and improve a patient's quality of life.

 

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Author Biographies

Dr Anuradha Kapoor AJPRD, Senior Resident, General Medicine Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

Senior Resident, General Medicine Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

Dr Mitva Agarwal, Senior Resident, ENT Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

Senior Resident, ENT Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

Dr Kanika Maheshwari, Senior Resident, Pathology Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

Senior Resident, Pathology Department, Dr N.C. Joshi Memorial Hospital, Govt. of N.C.T. of Delhi, Karol Bagh, New Delhi

References

Palange AA, Shahid AM, Sisode MS, Vaishnav B. Kartagener’s syndrome: case report. Int J Healthcare Biomed Res. 2013; 2(1):67–69.

Ahmed Z, Waseem W, Saman U. Kartagener’s syndrome presenting as bilateral recurrent nasal polyposis in a young boy. J Bahria Univ Med Dent Coll 2018; 8(4):274–277.

Siewert AK. Ueber einen Fall van Bronchiectasie bei einem patienten mito Situs inversus viscerum. Berlin Klin Wochen schr 1904; 6:139–141.

Kartagener M. Zur pathogenese der bronchiektasien. Beiträge zur Klinik der Tuberkulose und spezifischen Tuberkulose-Forschung 1933; 84(1–2):73–85. doi: 10.1007/BF02140428.

Tadesse A, Alemu H, Silamsaw M, Gebrewold Y. Kartagener’s syndrome: a case report. J Med Case Rep 2018;12(1):1–4. doi: 10.1186/s13256-017-1538-2.

Casanova MS, Tuji FM, Yoo HJ, Haiter-Neto F. Kartagener syndrome. Dentomaxillofacial Radiol 2006; 355:386–389. doi: 10.1259/dmfr/58545230.

Rugină AL, Dimitriu AG, Nistor N, Mihăilă D. Primary ciliary dyskinesia diagnosed by electron microscopy in one case of Kartagener syndrome. Rom J Morphol Embryol 2014; 55(2):697–701.

Leigh MW, Pittman JE, Carson JL, et al. Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome. Genet Med 2009; 11(7):473–487. doi: 10.1097/GIM.0b013e3181a53562.

Pandey AK, Maithani T, Bhardwaj A. Kartagener’s syndrome: a clinical reappraisal with two case reports. Egyptian J Ear Nose Throat Allied Sci 2014;15(3):271–274. doi: 10.1016/j.ejenta.2014.06.001.

Pandit S, Choudhury S, Das A, Basuthakur S, Das SK. A rare case of Kartagener’s syndrome. J Nat Sci Biol Med 2014; 5(1):175. doi: 10.4103/0976-9668.127321.

Corbo GM, Foresi A, Bonfitto P, Mugnano A, Agabiti N, Cole PJ. Measurement of nasal mucociliary clearance. Arch Dis Child 1989;64(4):546–50. doi: 10.1136/adc.64.4.546.

Dalrymple RA, Kenia P. European respiratory society guidelines for the diagnosis of primary ciliary dyskinesia: a guideline review. Arch Dis Child Educ Pract 2018; 104(5). doi: 10.1136/archdischild-2017-312902.

Camner P, Mossberg B, Afzelius BA. Measurements of tracheobronchial clearance in patients with immotile-cilia syndrome and its value in differential diagnosis. Eur J Respir Dis 1983; 127:57–63.

Skeik N, Jabr FI. Kartagener syndrome. Int J Gen Med 2011; 4:41. doi: 10.2147/IJGM.S16181.

Najafi S, Mohammadpour A, Eshghizadeh M. Kartagener syndrome: a case report. Asian J Pharm Clin Res 2018; 11(5):7–9. doi: 10.22159/ajpcr.2018.v11i5.25593.

Wang B, Zhang X, Jiang W, et al. Double lung transplantation for end-stage Kartagener syndrome: a case report and literature review. J Thorac Dis 2020;12(4):1588. doi: 10.21037/jtd.2020.02.28

Published

2024-12-15

How to Cite

AJPRD, D. A. K., Dr Mitva Agarwal, & Dr Kanika Maheshwari. (2024). Kartagener Syndrome: A Case Report. Asian Journal of Pharmaceutical Research and Development, 12(6), 71–79. https://doi.org/10.22270/ajprd.v12i6.1459

Issue

Vol. 12 No. 6 (2024): Volume 12 Issue 6 Nov- Dec. 2024

Section

Case Report

Copyright (c) 2024 Dr Anuradha Kapoor AJPRD, Dr Mitva Agarwal, Dr Kanika Maheshwari

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