Chewable Tablets: A Comprehensive Review
DOI:
https://doi.org/10.22270/ajprd.v12i4.1451Abstract
Tablets that can be chewed between the teeth must be broken before consumption. These tablets are provided to individuals who like swallowing and to youngsters who have difficulty swallowing. These tablets are designed to dissolve smoothly and quickly in the mouth, either with or without chewing. Typically, chewable tablets have a smooth texture when they dissolve, have a fruity flavour, and leave no bitter or unpleasant taste. Tablets that can be chewed between the teeth must be broken before consumption. These tablets are provided to individuals who like swallowing and to youngsters who have difficulty swallowing. These tablets are designed to dissolve smoothly and quickly in the mouth, either with or without chewing. Typically, chewable tablets have a smooth texture when they dissolve, have a fruity Flavour, and leave no bitter or unpleasant taste. Tablets that can be chewed between the teeth must be broken before consumption. These tablets are provided to individuals who like swallowing and to youngsters who have difficulty swallowing. These tablets are designed to dissolve smoothly and quickly in the mouth, either with or without chewing. Typically, chewable tablets have a smooth texture when they dissolve, have a fruity flavour, and leave no bitter or unpleasant taste.
Downloads
References
Chinwala M.Recent formulation advances and therapeutic usefulness of orally disintegrating tablets (ODTs). Pharmacy(Basel).2020;8(4):186.
Rajesh M, Varghese BS, PR SQ. Formulation and evaluation of sugar free sucralfate chewable tablets. World J Pharm Res. 2017 Sep 11;6(14):846-58.
Nasser N. Nyamweya and Samantha N. Kimani, Chewable Tablets: A Review of Formulation Considerations, Pharmaceutical Technology, 2020; 44(11):38-44.
Kaur G, Singh M, Matsoukas T, Kumar J, de Beer T, Nopens I. Two-compartment modeling and dynamics of top-sprayed fluidized bed granulator. Appl Math Model. 2019; 68:267-280.
Taranum R, Mittapally S. Soft chewable drug delivery system: Oral medicated jelly and soft chew. Journal of Drug Delivery Therapeutic 2018; 8(4):65-72.
Al-Kasmi B, Alsirawan MB, Bashimam M, El-Zein H. Mechanical microencapsulation: The best technique in taste masking for the manufacturing scale-Effect of polymer encapsulation on drug targeting. J Control Release. 2017; 260:134-141.
Ozkan G, Franco P, de Marco I, Xiao J, Capanoglu E. A review of microencapsulation methods for food antioxidants: Principles, advantages, drawbacks and applications. Food Chem. 2019; 272: 494-506.
Song H, Moon C, Lee BJ, Oh E. Mesoporous pravastatin solid dispersion granules incorporable into orally disintegrating tablets. J Pharm Sci. 2018; 107(7):1886-1895.
Liu T, Wan X, Luo Z, Liu C, Quan P, Cun D, et al. A donepezil/cyclodextrin complexation orodispersible film: Effect of cyclodextrin on taste-masking based on dynamic process and in vivo drug absorption. Asian J Pharm Sci. 2019; 14(2):183-192.
Sheaikh SS, Gaikwad RP, Shaikh AA, Pawar YD, Gavit BD. Solubility enhancement of etodolac chewable tablet using honey, and evaluation with (Doe) Design of experiment. Acta Sci Pharm Sci. 2018; 2(6):199-205.
Amit Antil, Monika Dahiya, Deepali Tomar, An Overview on Efficacy of Chewable Tablets in Improving Oral Drug Delivery,Systematic Review Pharmacy,2023; 14(9):571-577.
Dr. Vedprakash Patil,A Review on Chewable Tablet, International Journal of Pharmaceutical Research and Applications, 2023; 8(1):599-613.
Wafa M. Al-Madhagi, Arwa Alshargabi, Abdulkarim K. Y. Alzomor, and Olla Sharhan,Formulation of New Chewable Oral Dosage Forms of Meclizine and Pyridoxine Hydrochloride,Ady Pharmacology Pharm Sci. 2023:2023:5512379.
Saikishore Meruva, Aditya B Singaraju, Bhavani Prasad Vinjamuri, Robert Ternik, William C Stagner, Current State of Minitablet Product Design: A Review. Journal of Pharmaceutical Sciences, 2024.
Robert G Strickley, Pediatric oral formulations: an updated review of commercially available pediatric oral formulations since 2007. Journal of Pharmaceutical Sciences, 2019; 108 (4), 1335-1365.
Lisa Zieschang, Martin Klein, Nathalie Jung, Johannes Krämer, Maike Windbergs, Formulation development of medicated chewing gum tablets by direct compression using the SeDeM-Diagram-Expert-System. European Journal of Pharmaceutics and Biopharmaceutics,2019; 144:68-78.
Shubhrat Maheshwari, Aditya Singh, Aditya Prakash Varshney, Anurag Sharma, Advancing oral drug delivery: The science of fast dissolving tablets (FDTs). Intelligent Pharmacy, 2024.
Penelope N Rampedi, Modupe O Ogunrombi, Oluwatoyin A Adeleke, Leading Paediatric Infectious Diseases—Current Trends, Gaps, and Future Prospects in Oral Pharmacotherapeutic Interventions. Pharmaceutics,2024; 16 (6):712.
ALSayyed AN Sallam, Derar M Omari, Recent developments in pediatric and geriatric dosage forms. Novel Formulations and Future Trends, 2024; 267-293.
Yangbo Song, Xiaoli Ren, Lili Zhao, Biying Zhang, Wei Chi, Yanlin Liu, Kan Shi, Shuwen Liu, Foodomics uncovers functional and volatile metabolite dynamics in red raspberry chewable tablet optimized processing. Food Chemistry, 2024; 450:139379.
Published
How to Cite
Issue
Section
Copyright (c) 2024 Swapnil Sandip Shingade, Trushali A. Mandhare, Pooja S. Kashid, Kishor Otari
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).