Formulation and Evaluation of Herbal Tablets for the Treatment of PCOD using Kanchnar and Shatavari
DOI:
https://doi.org/10.22270/ajprd.v12i4.1438Abstract
Herbal tablets have been crucial in managing and preventing illnesses for centuries. Across cultures, herbs have advanced healthcare, leading to detailed herbal pharmacopeias. Integrating into mainstream healthcare, herbal tablets, especially Ayurvedic ones, are made from natural ingredients like Kanchanara and Shatavari, which are effective against Polycystic Ovary Disease (PCOD) by regulating cyst size and balancing hormones. Excipients in tablet formulations ensure correct dosage, integrity, and effective drug release. This underscores the growing importance of herbal medicine in modern healthcare. The meticulous selection of excipients, such as diluents, binders, disintegrants, and lubricants, is critical in the production of herbal tablets. Diluents add bulk to the tablet, binders ensure the tablet remains intact post-compression, disintegrants aid in the tablet's dissolution for effective drug release, and lubricants prevent sticking during manufacturing. Every excipient is selected based on its suitability and capacity to improve the tablet's characteristics, guaranteeing that the finished product is safe to eat and efficient. Moreover, the acceptability and widespread usage of herbal tablets demonstrate their potential to treat a variety of medical ailments. The ability of Shatavari and Kanchanara to treat PCOD, a condition marked by ovarian cysts and hormonal abnormalities, is evidence of the medicinal value of herbal medicine. Herbal pills are expected to become even more important in modern healthcare as research on the health benefits of various herbs continues, providing natural and holistic alternatives to traditional treatments.
Downloads
References
Mukherjee, P. K., & Wahile, A., et al. (2006). Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. Journal of ethnopharmacology, 103(1), 25-35.
Patwardhan, B., & Mashelkar, R. A., et al ., (2009). Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Drug discovery today, 14(15-16), 804-811.
Eisenberg, D. M., Davis, R. B., Ettner, S. L., et al. (1998). Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA, 280(18), 1569-1575.
Frawley, D., & Lad, V., et al,.(2001). The Yoga of Herbs: An Ayurvedic Guide to Herbal Medicine. Lotus Press.
Allen, L. V., & Ansel, H. C., et al,. (2013). Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. Wolters Kluwer Health.
Patel M, Patel NM, and Patel KR ,et al.,. Formulation and Evaluation of Polyherbal Tablets for the Treatment of Liver Disorders. Journal of Applied Pharmaceutical Science, 2011, 01 (05), pp. 166-169.
Sharma M, Agrawal S, Sharma PR, Chadha BS, Khatri P, Sharma S, et al,. Antioxidant and anti-inflammatory activities of Bauhinia purpurea and its compounds: a review. Journal of Integrative Medicine. 2018;16(5):337-45.
Kumar M, Pandey AK, Singh S, et al,. Antioxidant, analgesic and anti-inflammatory activities of Asparagus racemosus (Willd.) root. Indian Journal of Experimental Biology. 2009;47(4):270-5.
Sujata Kar, Dinesh Kumar, Bijay Kumar Padhi, Gopabandhu Jena, B. K. Mishra ,et al,. Polycystic Ovarian Disease: A Review. International Journal of Pharmaceutical Sciences and Research. 2011;2(1):25-34.
Stein, I. F., & Leventhal, M. L., et al. (1935). Amenorrhea associated with bilateral polycystic ovaries. American Journal of Obstetrics & Gynecology, 29(2), 181-191.
Teede, H. J., Misso, M. L., Costello, M. F., et al. (2018). Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Human Reproduction, 33(9), 1602-1618. doi:10.1093/humrep/dey256.
Escobar-Morreale, H. F., et al., (2018). Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nature Reviews Endocrinology, 14(5), 270-284.
Legro, R. S., Arslanian, S. A., Ehrmann, D. A., et al. (2013). Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 98(12), 4565-4592.
Azziz, R., Carmina, E., Chen, Z., et al. (2016). Polycystic ovary syndrome. Nature Reviews Disease Primers, 2, 16057.
Lizneva, D., Suturina, L., Walker, W., Brakta, S., Gavrilova-Jordan, L., & Azziz, R., et al., (2016). Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertility and Sterility, 106(1), 6-15. doi:10.1016/j.fertnstert.2016.05.003.
Mills, S., & Bone, K., et al., (2000). Principles and Practice of Phytotherapy: Modern Herbal Medicine. Churchill Livingstone.
Published
How to Cite
Issue
Section
Copyright (c) 2024 Sonali Kalam, Rupali Chaure, Poonam Dapke, Sandip Gorade, Saurabh Kale, Tushar Khore, Dr. Gajanan Sanap
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.