A Review of the Synthetic Account of 3-Methyl Pyrazolone as Anti-Inflammatory Agent

Authors

  • Chitnis Akshata Nandkumar Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India
  • Jadhav Kiran Mahadev Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India
  • Khandare Aishwarya Vishweshvar Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India
  • P. L. Salve Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India
  • V. J. Pise Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

DOI:

https://doi.org/10.22270/ajprd.v11i3.1427

Abstract

Pyrazolone is a five-membered lactam ring containing two nitrogens and one ketonic group in its structure. Numerous pyrazolone derivatives were exhibited with diverse biological, pharmacological, and chemical applications. The chemistry of pyrazolone has gained increasing attention due to its diverse pharmacological properties such as anticancer, analgesic, anti-inflammatory, antimicrobial, antioxidant, antifungal, antiviral, antidiabetic, and several other biological activities. Thus, because of their importance, synthetic strategies for existing as well as novel pyrazolone derivatives have been developed and explored their biochemical utility. Medicinal chemistry researchers have synthesized drug-like pyrazolone candidates with several medicinal features. This review paper intends to collect the references and comprehensively summarize the biological activity and the synthetic account of 3-methyl pyrazolone as an anti-inflammatory agent.


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Author Biographies

Chitnis Akshata Nandkumar, Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Jadhav Kiran Mahadev, Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Khandare Aishwarya Vishweshvar, Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India       

P. L. Salve, Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India       

V. J. Pise, Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India

Arvind Gavali College of Pharmacy, Jaitapur, Satara 415004, India       

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Published

2024-06-16

How to Cite

Nandkumar, C. A., Mahadev, J. K., Vishweshvar, K. A., Salve, P. L., & Pise, V. J. (2024). A Review of the Synthetic Account of 3-Methyl Pyrazolone as Anti-Inflammatory Agent. Asian Journal of Pharmaceutical Research and Development, 12(3), 230–238. https://doi.org/10.22270/ajprd.v11i3.1427