A Technical Note: On Niosomes

Authors

  • Rajput J. Vrunda Vidyabharti College of Pharmacy, Amravati, Maharashtra.
  • Gawai G. Anuja Vidyabharti College of Pharmacy, Amravati, Maharashtra.
  • Sable P. Rupali Vidyabharti College of Pharmacy, Amravati, Maharashtra.
  • Urkunde A. Subodh Vidyabharti College of Pharmacy, Amravati, Maharashtra.
  • Atram C. Dr. Sandeep Vidyabharti College of Pharmacy, Amravati, Maharashtra.

DOI:

https://doi.org/10.22270/ajprd.v12i1.1357

Abstract

A wide range of substances that serve as carriers can be suspended or captured by the Niosomes Delivery System (MDS), which can then be included into a designed product like a gel cream or powder. The formulation's primary goal is to get the desired medication concentration in the blood. Niosomes are a type of porous medication delivery device for small particles. They are tiny, spherical particles that resemble microscopic  and have a broad porous surface. In addition, they may increase stability by altering the drug's release pattern while minimizing negative effects. The serious condition impacting social life is acne vulgaris. Acne can be involved; alternation of follicular keratinization seldom causes significant systemic issues, but maturity, especially for women, which leads to drugs assist to reduce the production of sebum, which is mostly responsible for reducing the formation of acne on the skin. The use of niosomes as carriers for medications that target acne vulgaris is currently receiving more attention in research that focuses on illness detection and a brief to target acne vulgaris. Acne vulgaris is a serious condition that is currently affecting people's social lives. Increased sebum production, bacterial involvement, altered follicular keratinization, and altered follicular barrier are all characteristics of acne.  The current review is focused on the niosomes as carriers for the drug targeting the acne vulgaris, brief discussion on the present and future aspects of the niosomes  to targetet acne vulgaris.

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Author Biographies

Rajput J. Vrunda, Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Gawai G. Anuja, Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Sable P. Rupali, Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Urkunde A. Subodh, Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Atram C. Dr. Sandeep, Vidyabharti College of Pharmacy, Amravati, Maharashtra.

Vidyabharti College of Pharmacy, Amravati, Maharashtra.

References

Goodwin C. Anatomy and Physiology of the Skin. Journal of the Dermatology Nurses’ Association. 2011;3(4):203-13.

Agarwal R, Katare O.P, Vyas S.P. (2001). Preparation and in-vitro evaluation of liposomal or niosomal delivery systems for antipsoriatic drug dithranol. International Journal of Pharmaceutics, 228, 43-52

Agarwal R, Saraswat A, Kaur I, Katare O.P, Kumar B. (2002). A novel liposomal formulation of dithranol for psoriasis-Preliminary results. Journal of Dermatology, 29, 529-32.

Yousef H, Alhajj M, Sharma S. Anatomy, skin (integument), epidermis.

Nigam Y, Knight J. Anatomy and physiology of ageing 9: the immune system. Nursing Times. 2017;113:42-5.

Roshini A, Kumar RJ, Varshani S, Manikandan S, Nagalakshmi S. Design, Development, and Evaluation of Microsponge Loaded Topical Gel Using Design ExpertWith Benzoyl Peroxide for the Treatment of Acne Vulgaris. Journal of Cosmetic Science. 2022 Sep 1;73(5).

Lawton S. Skin 1: the structure and functions of the skin. Nurs. Times. 2019 Dec;115:30-3.

Patil PB, Datir SK, Saudagar RB. A review on topical gels as drug delivery system. Journal of Drug Delivery and Therapeutics. 2019 Jun 15;9(3-s):989-94.

Kumar D, Singh J, Antil M, Kumar V. Emulgel-novel topical drug delivery system-a comprehensive review. International journal of pharmaceutical sciences and research. 2016 Dec 1;7(12):4733.

Patel K, Patel R, Patel M. Formulation and characterization of microemulsion based gel of antifungal drug. PharmaTutor. 2014 Feb 1;2(2):79-89.

Bani KS, Bhardwaj K. Topical drug delivery therapeutics, drug absorption and penetration enhancement techniques. Journal of Drug Delivery and Therapeutics. 2021 Jul 15;11(4):105-10.

Islam J, Ganesh N, Kumar KU, Chandy V. Review on niosome as novel drug delivery system. Drugs. 2021 Mar 7;4:5.

Nasir A, Harikumar SL, Amanpreet K. Niosomes: An excellent tool for drug delivery. international journal of research in pharmacy and chemistry. 2012;2(2):479-87.

Sankhyan A, Pawar P. Recent Trends in Niosome as Vesicular DrugDelivery System. Journal of Applied Pharmaceutical Science. 2012 Jun 30(Issue):20-32.

Rai AK, Alam G, Singh AP, Verma NK. Niosomes: An aproach to current drug delivery-A review. International Journal of Advances in Pharmaceutics. 2017 Feb 28;6(2):41-8.

Yeo PL, Lim CL, Chye SM, Ling AP, Koh RY. Niosomes: a review of their structure, properties, method of preparation, and medical applications. Asian Biomed. 2017 Aug 1;11(4):301-14.

Makeshwar KB, Wasankar SR. Niosome: a novel drug delivery system. Asian journal of pharmaceutical research. 2013;3(1):16-20.

Soumya singh, Niosomes: a role in targeted drug delivery system, international journal of pharmaceutical sciences research,2013, vol 4(2);550-557.

Kaur dhanvir, kumar Sandeep, Niosomes: present scenario and future aspects, journal of drug delivery and therapeutics, 2018, vol 8(5);35-43.

V.shakya, B.K.Bansal, Niosomes: a novel trend in drug delivery, international journal of research and development in pharmacy and life sciences, 2014, vol 3;1036-1041.

Kumar A, Dua JS. Formulation and evaluation of itraconazole niosomal gel. Asian Journal of Pharmaceutical Research and Development. 2018 Oct 31;6(5):76-80.

Jayaraman SC, Ramachandran C, Weiner N. Topical delivery of erythromycin from various formulations: An in vivohairless mouse study. Journal of Pharmaceutical Sci., 1996; (85): 1082-1084.

Rohit SC, Manchanda R, Manchanda R. NATURAL POLYSACCHARIDES BASED NIOSOMES: A PROMISING DRUG DELIVERY SYSTEM.

Farroq U, Bashir I, Jamshaid M, Majeed I, Alvi MN, Siddiqui FA, Khan KI, Mehmood Y. Niosomes: A unique drug delivery tool. World J. pharm. Pharm. Sci. 2014 Sep 23;3:111-23.

Gayatri Devi S., Venkatesh P. and Udupa N. Niosomal sumatriptan succinate for nasal administration. Int. J. Pharm. Sci. 2000; 62(6), 479- 481.

Aravamudhan A, Ramos DM, Nada AA, Kumbar SG. Natural polymers: polysaccharides and their derivatives for biomedical applications. InNatural and synthetic biomedical polymers 2014 Jan 1 (pp. 67-89). Elsevier.

Rajeswari S, Prasanthi T, Sudha N, Swain RP, Panda S, Goka V. Natural polymers: A recent review. World J. Pharm. Pharm. Sci. 2017 May 31;6:472-94.

Charde et al. Development and evaluation of herbal formulation for the treatment of acne. IJPSR. 2014; 5(6):2250-2260.

Fatima Grace X, Vijetha J, Rahul Raj S, Shanthi S, Latha S, Shanmuganathan S. Formulation and evaluation of polyherbal anti-acne Gel. Advanced Journal of Pharmacy and Life Science Research. 2015;3(1):5-8.

Gunaydin A, Esenturk-Guzel İ, AlginYapar E, Yurdasiper A. Recent approaches in topical acne treatment and drug delivery. Journal of Research in Pharmacy. 2022 Nov 1;26(6).

Dawson AL, Dellavalle RP. Acne Vulgaris, BMJ 2013; 346: f2634.

Spencer EH, Ferdowsian HR, Barnard ND. Diet and Acne: A Review of the Evidence, Int J Dermatol 2009; 48(4):339–47.

Suva MA, Patel AM, Sharma N, Bhattacharya C, Mangi RK. A brief review on acne vulgaris: pathogenesis, diagnosis and treatment. Research & Reviews: Journal of Pharmacology. 2014;4(3):1-2.

Shrivastava B. Topical combination delivery of benzoyl peroxide and adapalene niosomal gel for acne treatment. Asian Journal of Pharmaceutics (AJP). 2019 Nov 7;13(04).

SONI S. Development and Screening of Isotretinoin Gel For The Treatment of Skin Problem Acne.

Ravisankar P, Koushik OS, Himaja V, Ramesh J, Pragna P. Acne-causes and amazing remedial measures for acne. J Pharm Res. 2015;5:209-301.

Published

2024-02-15

How to Cite

Vrunda, R. J., Anuja, G. G., Rupali, S. P., Subodh, U. A., & Sandeep, A. C. D. (2024). A Technical Note: On Niosomes. Asian Journal of Pharmaceutical Research and Development, 12(1), 107–118. https://doi.org/10.22270/ajprd.v12i1.1357