Review on 3-D Printed Drug Delivery Systems
DOI:
https://doi.org/10.22270/ajprd.v12i2.1340Abstract
Pharmaceutical of the field of sciences, 3D printed delivery of drug systems (DDS) arerevolutionizing field. With the using of additive printing techniques, these technologies enable the creation of complex, patient-specific drug delivery devices with specialized geometries, dosage schedules, and controlled release profiles. Since 3D printing may be used to customize drug formulations, dosage forms, and the mixing of many medications into a single device, it is a promising technique for improving therapeutic efficacy and decreasing side effects. This article discusses the application of several 3D printing methods include stereolithography (SLA) and fused deposition modelling (FDM) and selective laser sintering (SLS), in the production of implants, drug-loaded matrices, and devices for targeted or sustained drug release. Furthermore, challenges such as material.
Downloads
References
Moore CMV, Khan MA, Khairuzzaman A, Madurawe RD, Norman J. 3D-printed pharmaceutical items represent a new era in pharmaceutical manufacturing. Drug Deliv Advanc Rev. 2017;108:39-50.
Mahmoud AA, Maged A, Elkasabgy NA. An enticing option for personalized medication delivery systems is 3D printing. Int J Pharm. 2020;588:119732.
Hassanin H, Kayyali R, ElShaer A, Okafor-Muo OL. Solid oral dosage form 3D printing: many difficulties and special possibilities. J Pharm Sci. 2020;109:3535-3550.
Grasso A, Saviano M, Barile S, Aquino RP. Personalized medicine using 3D printing technology is an example of intelligent and sustainable healthcare. Futures. 2018;103:35-50.
Pierce A, Chiu L, Ursan I. Structured review of three-dimensional drug printing. J Am Pharm Assoc. 2013;53:136-144.
Sandler N, Preis M. Printed drug-delivery systems for better patient care. Pharmacol Sci Trends. 2016;37:1070-1080.
Moulton SE, Wallace GG. 3-dimensional (3D) drug delivery devices made of polymers. J Control Release. 2014;193:27-34.
Goyanes A, Martinez PR, Buanz A, Basit AW, Gaisford S. Personalized tablet 3D printing using fused deposition modeling. Int J Pharm. 2015;494(1):313-323.
Zhang J, Yang X, Yan Y, Xiong Z. Drug-loaded implants for long-term release can be 3D printed. J Control Release. 2017;258:147-155.
Wang J, Goyanes A, Gaisford S, Basit AW. 3D printing of oral solid dosage forms with improved bioavailability. J Pharm Sci. 2019;108(5):1623-1632.
Lee JW, Kim JY, Cho H, Park JH. 3D printing of transdermal patches for sustained release. J Control Release. 2018;273:134-141.
Khaled SA, Alexander MR, Wildman RD, Wallace MJ, Sharpe S, Yoo J, Roberts CJ. 3D printing of pharmaceuticals: A review. J Pharm Sci. 2018;107(11):2831-2843.
Li Q, Wang J, Shah U, Zhang X, Zhang J. 3D printing of drug delivery systems. J Control Release. 2018;269:242-254.
Norman J, Madurawe RD, Moore CMV, Khan MA, Khairuzzaman A. Regulatory considerations for 3D-printed pharmaceuticals. J Pharm Sci. 2019;108(5):1553-1561.
Goyanes A, Martinez PR, Buanz A, Basit AW, Gaisford S. Fused deposition modeling 3D printing of personalized tablets. Int J Pharm. 2015;494(1):313-323.
Zhang J, Yang X, Yan Y, Xiong Z. 3D printing of drug-loaded implants for sustained release. J Control Release. 2017;258:147-155.
Chai X, Chai W, Zhang Y, Zhang X, Hou X, Chen X. 3D printing of tablets with customized release profiles. Int J Pharm. 2017;521(1-2):346-355.
Kim J, Kim JY, Cho H, Park JH. 3D printing of transdermal patches for localized delivery. J Pharm Sci. 2019;108(10):3333-3341.
Park JH, Lee JW, Kim JY, Cho H. 3D printing of implants for sustained release. J Control Release. 2018;272:134-141.
Wu BM, Borland SW, Giordano RA, Cima LG, Sachs EM, Cima MJ. Solid free-form fabrication of drug delivery devices. J Control Release. 1996;40:77-87.
Gbureck U, Vorndran E, Müller FA, Barralet J. Low temperature direct 3D printed bioceramics and biocomposites as drug release matrices. J Control Release. 2007;122:173180.
Yu DG, Yang XL, Huang WD, Liu J, Wang YG, Xu H. Tablets with material gradients fabricated by three-dimensional printing. J Pharm Biomed Anal. 2007;44:486-496.
Yu DG, Yang XL, Huang WD, Liu J, Wang YG, Xu H. Tablets with material gradients fabricated by three-dimensional printing. J Pharm Biomed Anal. 2007;44:486-496.
Khaled SA, Burley JC, Alexander MR, Roberts CJ. Desktop 3D printing of controlled release pharmaceutical bilayer tablets. Int J Pharm. 2014;461:105-111.
Goyanes A, Buanz ABM, Hatton GB, Gaisford S, Basit AW. 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. Eur J Pharm Biopharm. 2015;89:157162.
Goyanes A, Wang J, Buanz ABM, Martinez-Pacheco R, Telford R, Gaisford S, et al. 3D printing of medicines: engineering novel oral devices with unique design and drug release characteristics. Mol Pharm. 2015;12:4077-4084.
Khaled SA, Burley JC, Alexander MR, Yang J, Roberts CJ. 3D printing of tablets containing multiple drugs with defined release profiles. Int J Pharm. 2015;494:643-650.
Khaled SA, Burley JC, Alexander MR, Yang J, Roberts CJ. 3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles. J Control Release. 2015;217:308-314.
Okwuosa TC, Stefaniak D, Arafat B, Isreb A, Wan KW, Alhnan MA. A lower temperature FDM 3D printing for the manufacture of patient-specific immediate release tablets. Pharm Res. 2016;33:2704-2712.
Acosta-Vélez GF, Linsley CS, Craig MC, Wu BM. Photocurable bioink for the inkjet 3D pharming of hydrophilic drugs. Bioengineering. 2017;4(1):11.
Genina N, Boetker JP, Colombo S, Harmankaya N, Rantanen J, Bohr A. Anti-tuberculosis drug combination for controlled oral delivery using 3D printed compartmental dosage forms: From drug product design to in vivo testing. J Control Release. 2017;268:4048.
Holländer J, Hakala R, Suominen J, Moritz N, Yliruusi J, Sandler N. 3D printed UV light cured polydimethylsiloxane devices for drug delivery. Int J Pharm. 2018;544:433-442.
Kollamaram G, Croker DM, Walker GM, Goyanes A, Basit AW, Gaisford S. Low temperature fused deposition modeling (FDM) 3D printing of thermolabile drugs. Int J Pharm. 2018;545:144-152.
Melocchi A, Parietti F, Loreti G, Maroni A, Gazzaniga A, Zema L. 3D printing by fused deposition modeling (FDM) of a swellable/erodible capsular device for oral pulsatile release of drugs. J Drug Deliv Sci Technol. 2015;30:360-367.
Gaurkhede SG, Osipitan OO, Dromgoole G, Spencer SA, Pasqua AJD, Deng J. 3D printing and dissolution testing of novel capsule shells for use in delivering acetaminophen. J Pharm Sci. 2021;110(12):3829-3837.
Russi L, Del Gaudio C. 3D printed multicompartmental capsules for a progressive drug release. J 3D Print Med. 2021;3:100026.
Maroni A, Melocchi A, Parietti F, Foppoli A, Zema L, Gazzaniga A. 3D printed multi-compartment capsular devices for two-pulse oral drug delivery. J Control Release. 2017;268:10-18.
Wu W, Zheng Q, Guo X, Sun J, Liu Y. A programmed release multi-drug implant fabricated by three-dimensional printing technology for bone tuberculosis therapy. Biomed Mater. 2009;4:065005.
Kempin W, Franz C, Koster LC, Schneider F, Bogdahn M, Weitschies W, et al. Assessment of different polymers and drug loads for fused deposition modeling of drug loaded implants. Eur J Pharm Biopharm. 2017;115:84-93.
Teo AL, Shearwood C, Ng KC, Lu J, Moochhala S. Transdermal microneedles for drug delivery applications. J Mater Sci Eng B. 2006;132(1):151-154.
Yadav PR, Dobson LJ, Pattanayek SK, Das DB. Swellable microneedles based transdermal drug delivery: Mathematical model development and numerical experiments. Chem Eng Sci. 2022;247:117005.
Waghule T, Singhvi G, Dubey SK, Pandey MM, Gupta G, Singh M, et al. Microneedles: A smart approach and increasing potential for transdermal drug delivery system. Biomed Pharmacother. 2019;109:1249-1258.
Chen Z, Wu H, Zhao S, Chen X, Wei T, Peng H, et al. 3D-printed integrated ultrasonic microneedle array for rapid transdermal drug delivery. Mol Pharm. 2022;19(9):3314-3322.
Elbadawi M, McCoubrey LE, Gavins FKH, Ong JJ, Goyanes A, Gaisford S, et al. Harnessing artificial intelligence for the next generation of 3D printed medicines. Adv Drug Deliv Rev. 2021; 175:113805.
[45] Bagde A, Dev S, Madhavi KSL, Spencer SD, Kalvala A, Nathani A, Salau O, Mosley-Kellum K, Dalvaigari H, Rajaraman S, Kundu A, Singh M. Biphasic burst and sustained transdermal delivery in vivo using an AI-optimized 3D-printed MN patch. Int J Pharm. 2023;636:122647.
Meng F, Hasan A, NejadiBabadaei MM, Hashemi Kani P, Jouya Talaei A, Sharifi M, et al. Polymeric-based microneedle arrays as potential platforms in the development of drug delivery systems. J Adv Res. 2020;26:137-147.
Khosraviboroujeni A, Mirdamadian SZ, Minaiyan M, Taheri A. Preparation and characterization of 3D printed PLA microneedle arrays for prolonged transdermal drug delivery of estradiol valerate. Drug Deliv Transl Res. 2022; 12(5):1195-1208.
Ha JH, Kim JY, Kim D, Ahn J, Jeong Y, Ko J, et al. Multifunctional micro/nanofiber based-dressing patch with healing, protection, and monitoring capabilities for advanced wound care. Adv Mater Technol. 2023;8(7):2201765.
Al-Kubaisi MW, Al-Ghurabi BH, Alkubaisy W, Abdullah NN. Anti-inflammatory effects of manuka honey on salivary cytokines (clinical study). JBCD. 2023;35(1):10-19.
Brites A, Ferreira M, Bom S, Grenho L, Claudio R, Gomes PS, et al. Fabrication of antibacterial and biocompatible 3D printed Manuka-Gelatin based patch for wound healing applications. Int J Pharm. 2023;632:122541.
Kim J, Lee J, Kim B. Fabrication of microneedles using 3D printing technology. J Control Release. 2004;97(2):247-254.
Park JH, Lee JW, Kim YC, Prausnitz MR. 3D printing of microneedles for transdermal drug delivery. J Pharm Sci. 2007;96(10):2801-2814.
Here are the references in Vancouver style:
Goyanes A, Buanz ABM, Hatton GB, Gaisford S, Basit AW. Fused deposition modeling 3D printing of personalized microneedles. Int J Pharm. 2015;494(1):313-323.
Zhang J, Wang X, Liu T, Liu J. 3D printing of microneedles for sustained release of drugs. J Control Release. 2017; 258:147-155.
Wang J, Goyanes A, Gaisford S, Basit AW. 3D printing of microneedles with controlled release profiles. J Pharm Sci. 2019 May; 108(5):1623-1632. doi: 10.1016/j.xphs.2019.02.006.
Published
How to Cite
Issue
Section
Copyright (c) 2024 Anuksh Telrandhe, Ketki Phadnis, Nilakshi Dhoble, Nitin Padole, Jagdish Baheti
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.