In Vitro Inhibition Assessment of Acetyl Cholinesterase by Mahabhutarava Ghrta
DOI:
https://doi.org/10.22270/ajprd.v11i6.1337Keywords:
Mahabhutaravaghrta, Acetylcholinesterase, Schizophrenia, UnmadaAbstract
Psychiatric disorders can make a huge negative impact not only to the patient but also to the family and his society. Schizophrenia is one among them that may lead to alteration in cognition and conation. Ayurveda considers the usage of ghrta preparations as the best strategy for the management of such psychiatric ailments. In the present study, a ghrta yoga, Mahabhutaravaghrta which had been in practise for the management of Schizophrenia and other psychiatric conditions was selected and an invitro inhibition assessment of Acetylcholinesterase has been planned. If inhibition is identified in the ghrta, it can justify the clinical efficacy of the drug in the patients.
Downloads
References
2. Niraj Ahuja. A Short Textbook of Psychiatry. 7th ed. Jaypee Brothers medical publishers, (p) Ltd; 2011; p.65.
3. Praveen Tripathi. Review of Psychiatry.4th ed. Jaypee Brothers Medical Publishers; 2019; p.17.
4. Benjamin James Sadock, Virginia Alcott Sadock. Kaplan &Sadock’s Synopsis of Psychiatry-Behavioral Sciences /Clinical psychiatry.11th ed. Lippincott Williams & Wilkins; 2015; p.318.
5. Benjamin James Sadock, Virginia Alcott Sadock. Kaplan & Sadock’s Synopsis of Psychiatry-Behavioral Sciences /Clinical psychiatry.11th ed. Lippincott Williams & Wilkins; 2015; p.320.
6. Harisāstri Parādakara editor. Aṣṭaṅga Hrdayam Sūtrasthāna of Vāgbhaṭa (Sarvāṅgasundara, Aruṇadatta, Āyurvedarasāyana, Hemādri, Comme, Sanskrit) 10th ed.Varanasi: Choukhambha Orientalia; 2011; p.243. 16/2.
7. Archanamadhavi et al. A critical review on the usage of ghrta in Unmada. J BiolSciOpin 2016: 4 (4): p. 148-52.
8. HarisāstriParādakara editor. Aṣṭaṅga Hrdayam Uttarasthāna of Vāgbhaṭa (Sarvāṅgasundara, Aruṇadatta, Āyurvedarasāyana, Hemādri, Comme, Sanskrit) 10th ed.Varanasi: Choukhambha Orientalia; 2011; p.795. 5/20.
9. Chi UnPae. Role of cholinesterase inhibitors in the treatment of Schizophrenia. Expert OpinInvestig Drugs.2013 Mar; 22 (3):293-8.
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).