Phytochemical Screening and Antibacterial Activity of Syzygium cumini (L.) (Myrtaceae) Leaves Extracts
DOI:
https://doi.org/10.22270/ajprd.v9i5.1023Keywords:
Syzygium cumini (L.) (Myrtaceae) Leaves Extracts, Phytochemical Screening, Antiviral, antibacterial and anti-tumor activities.Abstract
The phytochemical analysis of the medicinal plants are important and have commercial interest in both research institutes and pharmaceutical companies for the manufacturing of the new drugs for treatment of various diseases. The present study was aimed to investigate the preliminary phytochemical screening of the seeds of Syzygium cumini belonging to family Myrtaceae. The results revealed the presence of medicinally important phytochemical constituents in the ethyl acetate and methanol extracts of Syzygium cumini seeds and it justifies their use in the traditional medicines for the treatment of different diseases.
Phytochemical investigation was carried out on the crude methanol and aqueous extracts of the leaves of Syzygium cumini (L.) The antimicrobial activity of the extract was tested against standard strains and clinical isolates of some bacteria using the disc diffusion method. Preliminary phytochemical studies revealed the presence of flavonoids, alkaloids, glycosides, steroids, phenols, saponins, terpenoid, cardiac glycosides and tannins as the chemical class present in the extracts. The extracts showed inhibitory activity against clinical isolates of the gram negative bacteria such as Salmonella enteritidis, Salmonella typhi, Salmonella typhi A, Salmonella paratyphi A, Salmonella paratyphi B, Pseudomonas aeruginosa and Escherichia coli. Gram positive bacteria are Bacillus subtilis, and Staphylococcus aureus. The results showed that the methanol extracts was more potent than the aqueous extracts.
Downloads
References
2. Ncube and Okoh ,Assessment techniques of antimicrobial properties of natural compounds of plant origin current methods and future trends. African Journal of Biotechnology 2008; 7(12):1797-1806.
3. Krishnaiah D, Sarbatly R and Bono ,A Phytochemical antioxidants for health and medicine A move towards nature. Biotechnology Molecular Biology Reviews 2007; 1 97-104.
4. Martinez SB and Del Valle MJ Storage stability and sensory quality of duhat Syzygium cumini Linn anthocyanins as food colorant, UP Home. Economic Journal 9 1.5.Hanshella, C., Magno, R., Villasenor, I.M., Harada, N. and Monde, K. (1981). 2005,
5. Antihyperglycaemic Flavonoids from Syzygium samarangense (Blume) Maerr and Perry, Phytotherapy Research, 19: 246-251.
6. Peter, T., Padmavathi, D., Sajini, R.J., Sarala, A, Syzygium samarangense: A Review on Morphology, Phytochemistry and Pharmacological Aspects, Asian Journal of Biochemical and Pharmaceutical Research, 2011;4(1):155-163.
7. Srivastava, R., Arun, K., Shaw and Kulshreshtha, K ,Triterpenoids and Chalcone from Syzygium samarangense, Phytochemistry, 1994; 38(3):687-689. 62: 1-5.
8. Kuo, Y.C., Yang, L.M., Lin, L.C.Isolation and Immunomodulatory Effect of Flavonoids from Syzygium samarangense, Planta Medica, 2004, 70 (12): 1237-1239.
9. Reddy, L.J. and Rose, B, Chemical Composition and Antibacterial Activity of The Volatile Oil from The Leave of Syzygium samarangense (Blum) Merr. & L.M. Perry, Asian Journal of Biochemical and Pharmaceutical Research, 2011; 3(1):263-269.
10. Nair, A.G.R., Krishnan, S., Ravikrishna, C. and Madhusudanan, K.P.New and Rare Flavonol Glycosides from Leaves of Syzygium samarangense, Fitoterapia, 1998; 70:148-151.
11. Ragasa, C.Y., Franco, F.C., Raga, D.D. and Shen, C., Chemical Constituen of Syzygium samarangense, Deer Pharma Chemica, 2014; 6(3): 256-260.
12. Harborne J.B., Phytochemical methods, A Guide to Modern Techniques of plant analysis, Chapman and Hall, London, Ltd, 1973; 49-188.
13. Trease G.E. and Evans W.C., A text book of pharmacognosy Academic press, London, 198 22-40.
14. Bhatia I.S. Bajaj K.L. and Ghangas G.S., Tannins in black plum seeds. Phytochemistry. 1971; 10(1):219- 220.
15. Aiyelaagbe O.O. and Osamudiamen P.M. Phytochemical screening for active compounds in Mangifera indica, Plant, Sci. Res, 2009; 2(1):11-13.
16. Callow R.K., Steroids. Proc. Royal, Soc London Series A, 1936; 157:194.
17. Haslem E., Plant polyphenols: Vegetable tannins revisied-chemistry and pharmacology of natural products. Cambridge University Press, 1989; 169.
18. Fridous A.J. Islam. S.N.L.M. and Faruque A.B.M., Antimicrobial activity of the leaves of Adhatoda vasica, Calatropis gigantium, Nerium odoratum and Ocimum sanctum. Bangladesh J. Bot. 1990:227.
19. Mahmoud I.I. Marzouk M.S.A. Moharram F.A. El- Gindi M.R. Hassan A.M.K., Acylated flavonol glycosides from Eugenia jambolana leaves, Phytochemistry, 58,1239-1244.
20. Timbola A.K. Szpoganicz B. Branco A. Monache F.D. Pizzolatii M.G., A new flavonol from leaves of Eugenia jambolana, Fitoterapia, 2002; 73:174-176.
Published
How to Cite
Issue
Section
AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
.