Asian Journal of Pharmaceutical Research and Development http://ajprd.com/index.php/journal <div class="aboutushome" align="justify"><strong>Asian Journal of Pharmaceutical Research and Development (AJPRD)</strong>&nbsp;is a new online international journal allowing free unlimited access to abstract and Full text. The journal is devoted to the promotion of pharmaceutical sciences and related disciplines. It seeks particularly (but not exclusively) to encourage pharmaceutical and allied research of tropical relevance and to foster multidisciplinary research and collaboration among scientists, the pharmaceutical industry and health the health care professionals. It will also provide an international plate form for the communication and evaluation of data, methods and findings in pharmaceutical sciences and related disciplines. Although primarily devoted to original research papers, the journal welcomes reviews on current topics of special interest and relevance.</div> <div class="aboutushome">&nbsp;</div> Asian Journal of Pharmaceutical Research and Development en-US Asian Journal of Pharmaceutical Research and Development 2320-4850 <p><strong>AUTHORS WHO PUBLISH WITH THIS JOURNAL AGREE TO THE FOLLOWING TERMS:</strong></p> <p>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank" rel="noopener">Creative Commons Attribution-NonCommercial 4.0</a> Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.</p> <p>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.</p> <p>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The <a href="http://opcit.eprints.org/oacitation-biblio.html" target="_blank" rel="noopener">Effect of Open Access</a>).</p> The Effect of Infusion Breadfruit Leaves (Artocarpus Altilis (Parkinson) Fosberg) On Blood Glucose Levels in Male Mice (Mus Musculus) Diabetes Mellitus Type 2 http://ajprd.com/index.php/journal/article/view/852 <p>Objective: The purpose of this study was to determine the content of secondary metabolite compounds contained in breadfruit leaf infusions which affect blood glucose levels and to determine the effective concentration of breadfruit leaf infusions which play a role in lowering blood glucose levels. Methods: The research method was carried out experimentally with the stages of making simplicia, making infusion, phytochemical screening and testing the breadfruit leaf infusion using the alloxan induction method. Antidiabetic testing was carried out in vivo on animal testing with 5 treatment groups (Na-CMC 1% w / v, Glibenclamide 0.65 mg / kg BW, breadfruit leaf infusion 300 mg / kg BW, 400 mg / kg BW, 500 mg / kg BW). Results: The results of phytochemical screening on breadfruit leaf infusion showed flavonoids, saponins and tannins. The results of the antidiabetic test with the alloxan induction method showed a decrease in blood glucose levels at the concentration of breadfruit leaf infusion 300 mg / kg BW, 400 mg / kg BW, 500 mg / kg BW. Conclusion: Breadfruit leaf infusion has an effect on reducing blood glucose levels in male type 2 diabetes mellitus mice.&nbsp;</p> Helen Anjelina Simanjuntak Kasta Gurning ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 1 4 10.22270/ajprd.v8i6.852 The Evaluation of Drug Related Problems to Patient of Bronchial Asthma Which Has Related With The Duration of Taking Care and Breath Frequency at RSUP Dr M Djamil Padang http://ajprd.com/index.php/journal/article/view/851 <p><strong>Objectives:</strong> Asthma patients often receive more than one drug and will increase the risk of the occurrence of effect or something unwanted. To deal with Drug-Related Problems (DRPs) in the hospital, the role of pharmacist is needed that is strongly committed and capable of dealing with DRPs is required. This study aims to identify and analyze the DRPs and the relations between DRP and length of stay and also the patient's breathing frequency at RSUP Dr M. Djamil Padang.</p> <p><strong>Data Sources Study Selection:</strong> This research is a descriptive research conducted retrospectively. Samples were obtained from patients medical record data during the 2017.</p> <p><strong>Summary of contents of the article:</strong> In this study 10 categories of DRPs were analyzed. DRP was occured 19% untreated indications and there was no significant relations between DRP and length of stay and there was no significant relations between DRP and the patient's breathing frequency.</p> <p><strong>Conclusion:</strong> The result of statistical test using Spearmen'rho P-value 0.482, there is no significant relation between Drug-Related Problems and length of stay that has the value P&gt;0,05 is the relations between Drug-Related Problems and the breathing of frequency.</p> <p>&nbsp;</p> Benny Kurniawan Kurniawan Suhatri S Oea Khairsyaf ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2021-01-28 2021-01-28 8 6 5 9 10.22270/ajprd.v8i6.851 Chemical Analysis Methods to Detect Pork DNA and Derivative Contents in Food: A Review http://ajprd.com/index.php/journal/article/view/850 <p><strong>Purpose:</strong> Indonesia is a country which the most Muslim population in the world. In Indonesia, Halal in food product are mainly priority. Food adulteration with elements of pork or its derivatives become a very important thing to be analyzed. Therefore, There are several analytical methods that can be used such as molecular biology techniques including PCR, FTIR, chromatography, and electronic nose. This method can provide information to the public in choosing food products that are halal and tested. This review article describes the analytical methods that can be used for determination pork contents and its derivatives using various methods.</p> <p><strong>Selection of Data Sources:</strong> In preparing this article review, literature study techniques was used by using primary data from international journals. The data was searched by used online media such as ScienceDirect, NCBI, Research Gate, Google Scholar, Pub Med, and E-Resources.</p> <p><strong>Conclusion:</strong> PCR method was the best method. It was sensitive, specific, simple, and economical. This method was suitable for confirm authenticity of food and detected of pork DNA in food products.</p> <p>&nbsp;</p> Lusiana Berti Rina Desni Yetti Ridho Asra ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 10 19 10.22270/ajprd.v8i6.850 Effect of Gel Formulation of Corn Silk Extract (Stigma Maydis) On Burn Wound Healing In Male White Rat http://ajprd.com/index.php/journal/article/view/821 <p><strong>Objectives:</strong> Burns are damage or loss of tissue caused by exposure to very high temperatures. This study was to determine the effect of gel formulation from corn silk (<em>Stigma maydis</em>) in healing burns in male white rats.</p> <p><strong>Data Sources Study Selection</strong>: This research is an experimental research of the effect of gel formulation from corn silk (<em>Stigma maydis</em>) in healing burns in male white rats</p> <p><strong>Summary of contents of the article:</strong> Five groups are used in this study. Group I (induced hot metal), group II (induced hot metal + gel base), group III (induced hot metal + 10% corn silk extract gel), group IV (induced hot metal + 15% gel of corn silk extract gel), group V (induced hot metal + B® gel). Observations were made for 21 days. The results of this study are the average % of burns healing on day 7, 14 and 21 : group I (27.29%, 63.03%, 100%), group II (35.39%, 60.16 %, 100%), group III (37.16%, 65.34%, 100%), group IV (36.89%, 68.23%, 100%), group V (32.81%, 66, 48%, 100%). The period of epithelialization of skin tissue are groups I, II, III on day 16, group IV on day 14 and group V on day 17. The mean results of the epithelialization scores for groups I, II, III, IV and V (2, 2, 3, 3, 3), the mean fibroblast score results (2,7, 2,9, 3, 3, 3), groups I, II, III, IV and V collagen fiber density groups I, II, III , IV and V (2,2, 2,8, 3,6, 3,9, 3,9). The two-way ANOVA statistical analysis test on % burn healing was not significant (p&gt; 0.05), and the one-way ANOVA statistical analysis test at the period of epithelialization was not significant (p&gt;0.05) and the histology of epithelialization and fibroblasts was not significant (p&gt;0.05), the density of collagen fibers was significant (p&lt;0.05).</p> <p><strong>Conclusion</strong>: The conclusion of this study is corn silk extract gel (<em>Stigma maydis</em>) 10% and 15% have the effect on the healing process of burns and can be formulated in gel dosage forms.</p> Nessa Nessa Noni Rahayu Putri Eka Fitrianda Elmitra Elmitra Ridho Asra ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 20 27 10.22270/ajprd.v8i6.821 Development of Information Systems Management of Pharmaceutical Preparations and Web-Based Medical Materials at Puskesmas, Medan City http://ajprd.com/index.php/journal/article/view/847 <p><strong>Objective:</strong> To determine the effect of web-based information systems on the management of pharmaceutical preparations and BMHP in Medan City Health Center.</p> <p><strong>Methods:</strong> This research is a descriptive study with comparative study data collection to see the effect of the SIFAMAS application (System Information Puskesmas) which is designed based on indicators of drug management before and after the application. The design of SIFAMAS as a web-based information system based on the waterfall model and evaluated using alpha and beta tests. This research was conducted in February-July 2020.</p> <p><strong>Results:</strong> Before using SIFAMAS, all Puskesmas had not met the standard for accuracy of the number of expired drugs according to the standard, only Puskesmas Mandala, Puskesmas that sent LPLPO on time in February, March, and April respectively 100%; 0%; and 16.67%, and all Puskesmas have not matched the conformity standard for real goods with stock cards. After using SIFAMAS, all Puskesmas did not have expired drugs (0%), delivery of LPLPO was on time (100%), and met the conformity standard for real goods with stock cards (100%). Alpha and beta test results show that SIFAMAS is acceptable and very feasible as a pharmaceutical preparation management information system.</p> <p><strong>Conclusion:</strong> SIFAMAS has a good effect and can solve problems related to the management of pharmaceutical preparations in Puskesmas.</p> <p>&nbsp;</p> Novriani E Harahap U Wiryanto W ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 28 32 10.22270/ajprd.v8i6.847 Anti-Inflammatory Activity Test of N-Hexane Fraction Cream (Rhaphidophora Pinnata (L.F) Schott.) on Carrageenan Induced Back Edema in Mice http://ajprd.com/index.php/journal/article/view/848 <p><strong>Objective: </strong>One of the medicinal plants used traditionally by Indonesians is Rhaphidophora pinnata (L.f.) Schott, Family Araceae. Based on hereditary experience, the use of herbal plants is considered quite effective in treating various diseases. The results of phytochemical screening showed that Rhaphidophora pinnata leaf extract contained triterpenoid/steroid compounds which were thought to be anti-inflammatory agents. Topical administration of drugs can increase bioavailability and drug efficacy by avoiding first-pass metabolism in the liver. The advantage of the desired local effect can also be achieved with the use of topical anti-inflammatory drugs.</p> <p><strong>Methods: </strong>The leaves were dried into simplicia and then the simplicia characterization was examined. Extracted by percolation method using 96% ethanol and concentrated by rotary evaporator, then fractionated with n-hexane and concentrated. Formulation and evaluation of creams with doses of n-hexane 2.5, 5 and 10% fractions were made. The method of measuring anti-inflammatory used in this study refers to the method of inflammation-associated edema.</p> <p><strong>Results: </strong>Evaluation of cream preparations F1, F2 and F3 stable during storage up to 12 weeks from organoleptic, homogeneity, pH (5.9-6.3), spreadability (2.42-2.80 cm2), good dispersibility and irritation test. The F2 formula is the best in terms of pH and cream spreadability tests. The comparative significance value of the anti-inflammatory activity test at F2 compared to hydrocortisone gel was not a significant difference (P&gt; 0.05).</p> <p><strong>Conclusion: </strong>Cream formulation F3 of the 5% dose of Rhaphidophora pinnata leaf hexane n fraction in the cream preparation has the same effectiveness as the comparison of hydrocortisone cream in the form of cream.</p> Hasyimi Walidah M Arianto Anayanti Yuandani Y ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 33 38 10.22270/ajprd.v8i6.848 In Vitro Anti-Diabetic Potential Extract Test of Seri (Muntingia Calabura, L.) Leaves http://ajprd.com/index.php/journal/article/view/874 <p><strong>Objective: </strong>The purpose of this study was to determine the potential of the ethanol extract of the of <em>Muntingia calabura</em>, L (<em>M. calabura</em>) leaves as an anti-diabetic tested by in-vitro using the α-glucosidase enzyme.</p> <p><strong>Methods:</strong> extraction by maceration, phytochemical screening using standard testing and testing for anti-diabetic potential were carried out in vitro with observations of inhibition % of the α-glucosidase enzyme from various concentrations of ethanol extract of <em>M calabura</em> (60, 120, 200 and 300 ppm) leaves and acarbose as a standard of comparison.</p> <p><strong>Results:</strong> Phytochemical screening showed the ethanol extract content of <em>M. calabura </em>leaves, namely alkaloids, flavonoids, tannins, saponins, triterpenoids and steroids. The ethanol extract of <em>M. calabura</em> leaves has potential as an anti-diabetic and the increase in concentration is directly proportional to its potential activity.</p> <p><strong>Conclusions:</strong> The ethanol extract of <em>M. calabura</em> leaves has various types of secondary metabolites such as alkaloids, flavonoids, triterpenoids and steroids, saponins and tannins and has potential as anti-diabetic.</p> <p>&nbsp;</p> Kasta Gurning Hilda Sinaga ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 39 41 10.22270/ajprd.v8i6.874 Formulation of Black Cumin (Nigella Sativa L.) Ethanol Extract Gel Preparation with Addition of Dimeticone as Hair Tonic http://ajprd.com/index.php/journal/article/view/875 <p><strong>Objective</strong>: This study aims to formulate a gel preparation for the ethanol extract of Black Cumin (<em>Nigella sativa</em> L.) with the addition of dimethicone as a hair tonic.</p> <p><strong>Methods</strong>: Characterization examinations of Black Cumin (<em>Nigella sativa</em> L.) simplicia were carried out. Simplicia is macerated using 80% ethanol and concentrated in a rotary evaporator then in a freeze dryer until the extract is thick. The concentrations taken are 3%, 5% and 7%. Then tested the simplicia characterization, rat hair growth activity and an evaluation of the preparations was carried out, namely the homogeneity, organoleptic test, and microbial contamination test.</p> <p><strong>Results</strong>: The results of the simplicia characterization test were water content of 6.63%, water soluble content of 24.64%, total ash content of 3.55% and acid insoluble ash content of 0.29%. Hair tonic preparations are stable in storage for up to 12 weeks from organoleptic, homogeneity. The hair growth activity of the ethanol extract hair tonic gel from 3 concentrations, the best was 7% (1.96 ± 0.00).</p> <p><strong>Conclusion</strong>: Black Cumin (<em>Nigella sativa</em> L.) ethanol extract gel has hair growth activity.</p> <p>&nbsp;</p> Wulansari S Reveny J Nainggolan M ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 42 45 10.22270/ajprd.v8i6.875 Fractination and Characterization of Pandan Jeronggi Fruit (Iris Domestica (L.) Goldblatt & Mabb) Ethanol Extracts As Well As Antibacterial Activities from Each Fraction http://ajprd.com/index.php/journal/article/view/814 <p><strong>Objectives</strong>: The research aims to find out antibacterial activity of ethanol extract, n-hexane fraction, ethylacetate fraction and residual fraction (water) of Pandan Jeronggi fruit against several types of bacteria.</p> <p><strong>Methods</strong>: Antibacterial activity test was carried out using the agar diffusion method by measuring the diameter of the clear zone around the paper disc.</p> <p><strong>Results: </strong>The results of the simplicia characterization and ethanol extract obtained water content of 9.23% and 19.13%. Phytochemical screening test results in thick extract there are alkaloids, flavonoids, glycosides, saponins, and tannins. Antibacterial activity test results shows the inhibition of gram-positive and gram-negative bacteria. Ethyl acetate fraction and ethanol extract have the highest antibacterial activity with a concentration of 500 mg/ ml inhibitory diameter of 13.68 mm for Sthaphylococcus aureus and 11.44 mm for pseudomonas aeruginosa bacteria. Ethanol extract in Sthaphylococcus aureus 12.12 mm and 10.76 mm for pseudomonas aeruginosa bacteria, while the remaining fraction shows not too high inhibitory properties such as ethanol extract and ethylacetate fraction which is 10.42 mm in Sthaphylococcus aureus and 9.24 for pseudomonas aeruginosa bacteria in the n-hexane fraction has no inhibitory power. The KKt results obtained from the ethyl acetate fraction contained three visual stains, with AlCl<sub>3</sub> spray two are also three stains, with ammonia vapor there are three stains, the compound contained in the ethyl acetate fraction suspected as an antibacterial activity is fenolik.</p> <p>&nbsp;</p> Marpaung J K Sitorus P Suryanto D ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 46 52 10.22270/ajprd.v8i6.814 Formulation of Black Cumin (Nigella Sativa L.) Ethanol Extract Gel Preparation with Addition of Dimeticone as Hair Tonic http://ajprd.com/index.php/journal/article/view/876 <p><strong>Objective</strong>: This study aims to formulate a gel preparation for the ethanol extract of Black Cumin (<em>Nigella sativa</em> L.) with the addition of dimethicone as a hair tonic.</p> <p><strong>Methods</strong>: Characterization examinations of Black Cumin (<em>Nigella sativa</em> L.) simplicia were carried out. Simplicia is macerated using 80% ethanol and concentrated in a rotary evaporator then in a freeze dryer until the extract is thick. The concentrations taken are 3%, 5% and 7%. Then tested the simplicia characterization, rat hair growth activity and an evaluation of the preparations was carried out, namely the homogeneity, organoleptic test, and microbial contamination test.</p> <p><strong>Results</strong>: The results of the simplicia characterization test were water content of 6.63%, water soluble content of 24.64%, total ash content of 3.55% and acid insoluble ash content of 0.29%. Hair tonic preparations are stable in storage for up to 12 weeks from organoleptic, homogeneity. The hair growth activity of the ethanol extract hair tonic gel from 3 concentrations, the best was 7% (1.96 ± 0.00).</p> <p><strong>Conclusion</strong>: Black Cumin (<em>Nigella sativa</em> L.) ethanol extract gel has hair growth activity.</p> <p>&nbsp;</p> Wulansari S Reveny J Nainggolan M ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 53 55 10.22270/ajprd.v8i6.876 Ovarian Cancer: Current Scenario, Treatment And Novel Strategies For Management http://ajprd.com/index.php/journal/article/view/880 <p>Ovarian cancer is the leading gynaecological cancer among women globally and leads to death with 5-year survival rate of metastatic form of ovarian cancer as only 20-30%. Detection of disease at an early stage is very difficult and no screening test are available for detection of OC in general population. For effective management of ovarian cancer chemotherapy, surgery, hormone therapy and radiation therapy are often used alone or in combination depending on the stage and severity of ovarian cancer. This mini-review describes about facts and figures as well as current diagnosis and treatment methods available for ovarian cancer. The manuscript will also cover a brief description of recent research of developing novel strategies such as liposomal drug delivery carriers in management of cancer.</p> <p>&nbsp;</p> Shreya Suthar Shryas Desai ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 56 60 10.22270/ajprd.v8i6.880 Combined Effects of % Er Coating and Ec: Pvp Ratio on Release Profile of Topiramate Extended Release Pellets http://ajprd.com/index.php/journal/article/view/882 <p>The main purpose of this study was to investigate the influence of %ER coating and EC: PVP ratio on the release profile of topiramate extended release pellets. This formulation comprises of an extended releasecomponent (ethyl cellulose) which retards the release of drug coated on the core pellets. The extent of extended release coat and concentration of extended release component is optimized to achieve predetermined dissolution profile. Formulating modified release drug delivery system for highly soluble drug is difficult.Presentresearchcomprisesofethylcelluloseactsasratecontrollinghydrophobicbarrier while povidone k-30 acts as pore former component which helps in release of drug. Reservoir technology by using wurster coating process was used to develop extended release pellets where, subsequent coating is applied on corepellets. In drug layering stage, drug solution prepared was dispersion solution. Therefore viscosity played animportantroleindruglayering. 4% barrier coating using Opadry clear was done to smoothen the drug layered pellets for the ease of subsequent coating process. Extended release coat applied on the barrier layer coated pellets, determines the release of the drug from the formulation. Thus, in present research ratio of EC: PVP K-30 and % ER coating were optimized to 75:15 and 13% respectively to obtain desired drug releaseprofile.</p> <p><strong>&nbsp;</strong></p> <p>&nbsp;</p> Vrunda Patel ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 61 72 10.22270/ajprd.v8i6.882 Microencapsulation to Maintain the Activity and Stability of Drug Substances: A Review http://ajprd.com/index.php/journal/article/view/829 <p><strong>Purpose: </strong>The microencapsulation method is one of the most widely used techniques to protect bioactive compounds from various environmental factors such as evaporation, oxidation, degradation of temperature, humidity, and light.&nbsp; Therefore, it can extend product shelf life and avoid damage so that it can last a long time and can still be utilized by the body well<sup>1</sup>.</p> <p><strong>Selection of Data Sources:</strong> In compiling a review, this article used a literature study by finding sources or literature in the form of national and international journals in the last 10 years (2010-2020). Data search was also carried out using online media with the keywords as follows: microencapsulation, microcapsules, and microencapsulation methods. The search for the main references used in this review article was conducted through trusted websites such as Science Direct, Pubmed, Google Scholar, and other published and trustworthy journals.</p> <p><strong>Conclusion:</strong> Based on the results of several studies, it can be concluded that microencapsulation using several of the above methods can provide protection for the substance / drug against environmental influences, and it can maintain the stability of a substance / drug so that it can extend the drug release time.</p> <p>&nbsp;</p> Sintia Ayu Almadanti Indra Makmur Ridho Asra Salman Umar ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 73 76 10.22270/ajprd.v8i6.829 The Application of Marine Natural Products (MNPS) In Anti-Covid-19 Therapeutics http://ajprd.com/index.php/journal/article/view/809 <p>The bioprospecting of MNPs for the treatment of COVID-19 virus was attempted. The marine biodiversity is a remarkable source of bioactive chemotherapeuticals. The structural uniqueness of selected MNPs was correlatedwith reported binding energies to ascertain structure activity relationship (SAR) features.</p> <p>&nbsp;</p> Rajendra Singh Pawar Mayank Dimri Alok Maithani Luv Kush ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 77 80 10.22270/ajprd.v8i6.809 Buckyballs In The Treatment of Alzheimer's Disease http://ajprd.com/index.php/journal/article/view/808 <p>Buckyball is the first nanoparticle discovered in the year 1985 by the trio scientists Richard Smalley, Harry Kroto, and Robert Curl. Buckyballs also called as fullerene. Fullerene is a powerful antioxidant that reacts with free radicals that cause cell death. Fullerenes and their derivatives have the Antiviral activity to treat the HIV infection. Two of the several brain changes that occur in Alzheimer’s disease are β-amyloid plaques and tau tangles present outside and inside the neurons respectively. The changes in brain, cerebrospinal fluid and blood indicate the earliest sign of Alzheimer's disease (biomarkers) even in the absence of memory loss. Ukrainian scientists discovered Carbon 60 or C-60 or Fullerene or Buckyballs. Through the microinjection C60HyFn (0.46nmol/µl) is injected into the hippocampus. It reduces the deposition of β-amyloid in the pyramidal neurons of hippocampal CA 1 neuron.</p> <p>&nbsp;</p> Akhila Yaramala Bhavana Samanthapudi ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 81 83 10.22270/ajprd.v8i6.808 Anti-Covid-19 Phytochemicals http://ajprd.com/index.php/journal/article/view/807 <p>The Phytochemicals are the future phytomedicine for Covid-19 virus, therefore their antiviral affinity was differently viewed.</p> <p>&nbsp;</p> Rajendra Singh Pawar Mayank Dimri Alok Maithani Luv Kush ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2020-12-15 2020-12-15 8 6 84 88 10.22270/ajprd.v8i6.807