@article{M_A_M_2020, title={Phytochemicals Analysis and Cytotoxicity Activity of Ethanol Extract of Litseacubeba Lour.Heartwood}, volume={8}, url={https://ajprd.com/index.php/journal/article/view/643}, DOI={10.22270/ajprd.v8i1.643}, abstractNote={<p> </p> <p>Objective: The purpose of this study was to determine the chemical compounds whichcontained in the ethanol extract and cytotoxic activity ethanol extract of <em>Litseacubeba </em>heartwood induced in T47D cells.</p> <p>Methods: The ethanol extract was extracted by maceration using ethanol 96% solvent. Cytotoxic activity was determined with MTT method and the IC<sub>50</sub>analyzed using SPSS 23.</p> <p>Results: Phytochemicals screening were showed that the ethanol extract of <em>Litseacubeba </em>heartwood contained steroids/triterpenoids, glycosides, alkaloids, flavonoids, saponins and tannins. The IC<sub>50</sub>of ethanol extract of <em>L</em><em>itseacubeba </em>heartwood were 349,57 ±0,35μg/ml in T47D cells.</p> <p>Conclusions: Ethanol extract of <em>L</em><em>itseacubeba </em>heartwood has activity as an anticancer to T47D cells breast cancer agents.</p> <p> </p>}, number={1}, journal={Asian Journal of Pharmaceutical Research and Development}, author={M, Fujiko and A, Dalimunthe and M, Masfria}, year={2020}, month={Feb.}, pages={14–17} }