The Correlation of Characteristics of Type 2 Diabetes Mellitus Patients and Medication Adherence Level: A Case Study in Community Pharmacy
Background: Patients with diabetes mellitus (DM) are patients with a low level of medication adherence. Low adherence causes poor glycemic control, thus increasing the risk of various chronic complications (microvascular and macrovascular).
Objective: This study aims to determine the correlation between patient characteristics including gender, age, education level, occupation, duration of illness, and comorbidities on medication adherence to type 2 diabetes mellitus patients at the pharmacy. Methods: This study used an observational method with a cross-sectional study design. The study involved 40 DM type 2 patients who met the inclusion criteria at one of the pharmacies in Medan in August-September 2020. Data on the level of treatment adherence were obtained using the MMAS-8 questionnaire (Morisky Medication Adherence Scale-8). Data were analyzed using the Chi-Square statistical test.
Results: The results showed that the majority of patients involved in this study were women (57.5%), aged 45-65 years (92.5%), high school education level (47.5%), and private employees/ traders/ labor (45%). This study also showed that the majority of patients had a low level of adherence (55%), duration of suffering from type 2 diabetes, 1-5 years (18%), and with comorbidities (75%). The relationship between patient characteristics and adherence level was gender (p = 0.636); age (p=0.922); education level (p=0.275); work (p=0.241); duration of illness (p=0.629); and with comorbidities (p=0.752) the level of treatment adherence was not significant (p>0.05).
Conclusion: Based on the results of the study it was concluded that there was no significant relationship between patient characteristics including gender, age, level of education, occupation, duration of disease, and comorbid diseases on the level of medication adherence of type 2 DM patients at the community pharmacy.
2. International Diabetes Federation. Diabetes Atlas. Ninth Edition. 2019. Available from: http://www.diabetesatlas.org
3. World Health Organization. Global report on diabetes. 2018. Available from: http://www.who.int/diabetes/global-report/en/.
4. Ministry of Health of the Republic of Indonesia. Basic health research of Republic of Indonesia Jakarta: Ministry of Health of the Republic of Indonesia. 2018.
5. Katadi S, Tri MA, Dwi E. The correlation of treatment adherence with clinical outcome and quality of life in patients with type 2 diabetes. Journal of Pharmaceutical Management and Pharmacy Practice. 2019; 9(1):19-26
6. Morisky DE, Ang A, Krousel-Wood MA, Ward H. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens. 2008; 10:348-354
7. Riastiena LP, Ikawati Z, Endarti D. Validation of 8-item morisky medication adherence scale in Indonesian version in type 2 diabetes mellitus patients at public health centers in Sleman Regency and Yogyakarta City. Thesis. Yogyakarta: Faculty of Pharmacy University of Gadjah Mada; 2017.
8. Alfian R. The correlation between medication adherence and blood sugar levels in outpatients with diabetes mellitus at RSUD Dr. H. Moch. Ansari Saleh Banjarmasin. Journal of Pharmascience. 2015; 2(2):15–23.
9. Rasdianah N, Martodiharjo S,Andayani TM, Hakim L. The Description of Medication Adherencefor Patients of Diabetes Mellitus Type 2in Public Health Center Yogyakarta.Indonesian Journal of Clinical Pharmacy.2016;5(4):249-257.
10. Ramadona A. The effect of counseling medication against patient compliance diabetes mellitus type 2. 2011.
11. Ponnusankar S, Surulivelrajan M,Anandamoorthy N, Suresh B. Assessmentof impact of medication counseling onpatients’ medication knowledge andcompliance in an outpatient clinic inSouth India. Patient Educ and Couns.2004; 54(1):55–60.
12. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005; 353:487–97.
13. Currie CJ, Peyrot M, Morgan CL, Poole CD, Jenkins-Jones S, Rubin RR, et al. The impact of treatment noncompliance on mortality in people with type 2 diabetes. Diabetes Care. 2012; 35(6):1279–84.
14. Pollack M, Chastek B, Williams S. Impact of treatment complexity on adherence and glycemic control: an analysis of oral anti-diabetic agents. Value Health.2009; 12(3):A103.
15. Cramer JA, Roy, Burrel A, et al. Medication compliance and persisten: terminology and definitions. Value Health. 2008; 11(1):44–7.
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