Anti Inflammatory Potential of Moringa Oleifera Lam. Bark In Jaipur Region

Authors

  • Nidhi Chauhan Arya college of Pharmacy, Kookas, Jaipur, Rajasthan, India
  • Vandana Sharma
  • Ramesh Pareek Arya college of Pharmacy, Kookas, Jaipur, Rajasthan, India
  • Ashish Kushwaha Pharmacy Institute, Noida Institute of Engineering & Technology 19, Knowledge Park-II, Institutional Area Greater Noida- 201306, Uttar Pradesh, India

DOI:

https://doi.org/10.22270/ajprd.v9i1.889

Keywords:

Moringa Oleifera Lam., Anti inflammation, Carrageenan induced, Egg albumin

Abstract

Objective: To investigate the anti-inflammatory potential of moringa oleifera lam. (M.Oleifera L.) bark crude ethanolic extract in regards to phytochemical studies . Method: compared tha anti-inflammatory effect of M.Oleifera L. at  (300, 200 and  100 mg/kg, p.o) doses with that of standard anti-inflammatory agent like diclofenac sodium at a dose of (10mg/kg, p.o) using carrageenan induced paw edema and egg albumin induced paw edema. Result: Hydroalcoholic extract of M.Oleifera L. stem bark at a dose of 300mg/kg p.o and 200mg/kg p.o showed a significant dose dependent as campare to 100mg/kg, further it was compared with the reduction of paw edema against standard drug diclofenac sodium at a dose of 10mg/kg p.o both in carrageenan induced and egg albumin induced paw edema. The decrease in the edema volume was seen over a period of time from 2nd, 3rd,  and 4thhour where the degree of edema was reduce. Conclusion: from the above findings it was observed that the hydroalcoholic extract of  M.Oleifera L.possess a significant anti-inflammatory activity against the animal model.

 

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Author Biographies

Nidhi Chauhan, Arya college of Pharmacy, Kookas, Jaipur, Rajasthan, India

Arya college of Pharmacy, Kookas, Jaipur, Rajasthan, India

Ramesh Pareek, Arya college of Pharmacy, Kookas, Jaipur, Rajasthan, India

Arya college of Pharmacy, Kookas, Jaipur, Rajasthan, India

Ashish Kushwaha, Pharmacy Institute, Noida Institute of Engineering & Technology 19, Knowledge Park-II, Institutional Area Greater Noida- 201306, Uttar Pradesh, India

Pharmacy Institute, Noida Institute of Engineering & Technology 19, Knowledge Park-II, Institutional Area Greater Noida- 201306, Uttar Pradesh, India

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Published

2021-02-15

How to Cite

Chauhan, N., Sharma, V., Pareek, R., & Kushwaha, A. (2021). Anti Inflammatory Potential of Moringa Oleifera Lam. Bark In Jaipur Region. Asian Journal of Pharmaceutical Research and Development, 9(1), 78–83. https://doi.org/10.22270/ajprd.v9i1.889

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