Synthesis of Schiff’s Bases With Simple Synthetic Approach

  • Nikam Dhiraj Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614
  • Nikam Rutuja Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614
  • Shinde Kalpesh Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614
  • Karande Sunil Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Abstract

A series of Schiff’s bases (3A-G) were synthesized using a simple synthetic approach.0.05 mole of  m-nitro aniline and aromatic aldehydes in ethanolic solution was subjected to refluxed for 2 hr to obtain pure products. All the products obtained were having excellent yield in the range of 80-90 % w/w. Products were purified using hot ethanol and reaction was monitored by hexane: ethyl acetate (60:40).

Keywords: Schiff’s bases, m-nitroaniline, aldehydes

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Author Biographies

Nikam Dhiraj, Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Nikam Rutuja, Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Shinde Kalpesh, Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Karande Sunil, Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai, Maharashtra, India 400 614

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How to Cite
Dhiraj, N., Rutuja, N., Kalpesh, S., & Sunil, K. (2020). Synthesis of Schiff’s Bases With Simple Synthetic Approach. Asian Journal of Pharmaceutical Research and Development, 8(5), 72-74. https://doi.org/https://doi.org/10.22270/ajprd.v8i5.837