A Review: Natural Resources as Natural Dyes in Pharmaceutical Products

Authors

  • Shintasya Novelia. D. A School of Pharmaceutical Science (STIFARM) Padang, Indonesia 25147
  • Ridho Asra School of Pharmaceutical Science (STIFARM) Padang, Indonesia 25147

DOI:

https://doi.org/10.22270/ajprd.v8i5.826

Keywords:

Beverages, Cosmetics, Food, Medicines, Natural dyes, Pharmaceutical products, Plants. and Octyl methoxycinnamate

Abstract

Objectives: Several types of natural dyes have been used in pharmaceutical products such as food, beverages, cosmetics and drug additives. Natural dyes are safe and do not cause allergies or irritation to the body. The benefits of natural dyes are as a substitute for synthetic dyes which are safer for the body. The purpose of this article is to discuss natural dyes that are applied or added to pharmaceutical products or the pharmaceutical industry.

Data Sources Study Selection: The review method used is by studying the literature relevant to the research. Data sources of this article were selectively taken from Google Schoolar, Pubmed, and Mandeley.

Summary of contents of the article:  Pharmaceutical products always Use coloring additives for consumer appeal. The addition of dyes to pharmaceutical products such as drugs will make it easier to distinguish between these types of drugs. Dyes that are safe for the body are chosen as a safe alternative in their use. Natural dyes can be derived from plants, minerals, and animals, many plants contain pigments and can be applied to pharmaceutical products such as food, beverages, cosmetics, and medicines. There are many kinds of pigments contained in plants and animals, such as flavonoids, tannins, alkaloids, indigoid, chlorophyll, and carotenoids.

Conclusion: The conclusion of this article is that natural dyes cannot only be used as a substitute for dyes that are safe for the body, but natural dyes also have pharmacological properties. The application of natural dyes to food, beverages, cosmetics and medicines does not affect the taste, aroma and texture of the product

 

Downloads

Download data is not yet available.

Author Biographies

Shintasya Novelia. D. A, School of Pharmaceutical Science (STIFARM) Padang, Indonesia 25147

School of Pharmaceutical Science (STIFARM) Padang, Indonesia 25147

Ridho Asra, School of Pharmaceutical Science (STIFARM) Padang, Indonesia 25147

School of Pharmaceutical Science (STIFARM) Padang, Indonesia 25147

References

1. Tayade, V, S. Patil, D. Pal, S., & Gaur, S, S. Medicinal Properties of Natural Colors / Dyes from Plants. AsianJournal of Advanced Basic Science. 2018; 6(3):42-48.
2. Pujilestari, T. Review: Sources and Utilization of Natural Dyes for Industrial Use. The dynamics of handicrafts and batik. 2015; 32(2):93-106.
3. Kumar, M. Venkatesh, P, M., & Kumar, P, M, T. Colourants And Additives: Existing and Emerging Safety Concerns. International Journal of Pharmaceutical and Clinical Research. 2017; 9(7):525-533.
4. Simon, E, J. Decker, A, E. Ferruzzi, G, M. Giusti, M, M. Mejia, D, C. Goldschmidt, M., & Talcott, T, S. Feature Article Establishing Standards on Colors from Natural Souces. Journal of Food Science. 2017; 82:11.
5. Srivastava, R & Singh, N. Importance of Natural Dye Over Synthetic Dye: A Critical Review. International Journal of Home Science. 2019; 5(2):148-150.
6. Šuleková, M. Smrčová, M. Hudák, A. Heželová, M., &Fedorová, M. Organic Coloring Agents in The Pharmaceutical Industry. Folia Veterinaria. 2017; 61(3):32-46.
7. Ali, F, N. Review of Eco Friendly and Protective Natural Dyes. World Journal of Pharmaceutical and Life Sciences. 2018;4(5):120-125.
8. Lakshmi, C. Food Coloring: The Natural Way. Research Journal of Chemical Sciences. 2014;(2):87-96.
9. Simanjuntak, L. Sinaga, C., & Fatimah. Extraction of Anthocyanin Pigments from the Peel of Red Dragon Fruit (Hylocereuspolyrhizus). USU's Journal of Chemical Engineering. 2014;3(2): 25-29.
10. Marlina, L. Putri, I, S. Utilization of Cocoa Bean Extract as Natural Dyes in Lipstick. Farmako. 2019;13(2):134-141.
11. Alvionita, J. Darwis, D., &Efdi, M. Extraction and Identification of Anthocyanin Compounds from Plantain Heart (Musa X paradisiac L.) and Antioxidant Activity Test. Journal of Chemical Research. 2016;9(2):21-28.
12. Sofyaningsih, M. Iswahyudi.Red Dragon Fruit Peel Extract Microencapsulation UsingTechniqueSpray Drying. ARGIPE. 2018;3(1):1-7.
13. Handayani, A, P. Rahmawati, A. Utilization of Dragon Fruit Peel as Natural Food Coloring to Substitute Synthetic Dyes. Journal of Renewable Natural Materials. 2012;1(2):19-24.
14. Fendri, J, T, S. Martinus, A, B., &Haryanti, D, M. Effect of pH and Temperature on Anthocyanin Stability of Purple Sweet Potato Peel Extract (Ipomea batatas (L.) Lam.). Chempublish Journal. 2018;2(2):33-41.
15. Santoso, A, E, W &Estiasih, T. Journal of Review: Copigmentation of Purple Sweet Potatoes (Ipomoea batatas var. Ayamurasaki) With NA-Caseinate and Whey Protein Copigment and Its Stability Against Heating. Journal of Food and Agroindustry. 2014;(4):121-127.
16. Winarti, S. Sarofa, U., &Anggrahini, D. Extraction and Color Stability of Purple Sweet Potatoes (Ipomea batatas L.,) as Natural Dyes. Journal of Chemical Engineering. 2008;3(1):207-2014.
17. Santi, N, R. Herawati, E., &Ambarwati, S, S, N. Formulation and evaluation of cosmetic preparations for lipstick dyes from secang stem bark extract (Caesalpinia sappan L.). 2020;10(1):72-82.
18. Nurcahyo, H &Kusnadi. Natural Dyes Macerated Rosella Flower Extract (Hibiscus sabdariffa L.). Scientific Journal of Pharmacy. 2019;8(1):61-64.
19. Setiawan, W, A, M. Nugroho, K, E., &Lestario, N, L. Extraction of Betacyaninfrom BeetrootPeel(Beta vulgaris)as Natural Dyes. AGRIC Journal of Agricultural Sciences. 2015;27(1):38-43.
20. Sabarudin, A, N. Munaim, A, S, M., & Wahid, A, Z. Effect of Extraction Condition of Natural Dye Pigment from Bougainvillea Flowers' Bract. Australian Journal of Basic and Applied Sciences. 2016;10(17):172-175.
21. Asra, R. Yetti, D, R. Misfadhila, S. Rusdi. Audina, S. Agustina, A., & Nessa. Antioxidant Activity of Dried Extracts of Dragon Fruit and Its Peel (Hylocereuslemairei (Hook) Britton & Rose). Higea Journal of Pharmacy. 2019;11(1):17-22.
22. Aanisah, N. Sulastri, E. Yusriadi. Friskilla., & Syamsidi, A. Utilization of Cactus Fruit Extract (Oputian elatior Mill.) As Natural Dyes in Lipstick Preparations. Journal of Science and Health. 2020;2(2):122-128.
23. Octaviani, T. Guntatarti, A., &Susanti, H. Determination of ß-Carotene levelsIn Several Types of Chili (Genus capsicum) Using Visible Spectrophotometric Method. Pharmaciana. 2014;4(2):101-109.
24. Christian.Extraction of Carotenoid Pigments in Crab Shells as Healthy Natural Dyes. Academic Scientific Journal of UMG. 2018;7(1):27-33.
25. Anam, C &Handajani, S. Waluh Dried Noodles (Cucurbita moschata) with Antioxidants and Natural Dyes. CarakaTani. 2010;25(1):72-78.
26. Rebecca, J, L. Sharmila, S. Das, P, M &Seshiah, C. Extraction and Purification of Carotenoids from Vegetables. Journal of Chemical and Pharmaceutical Research. 2014;6(4):594-598.
27. Fikselova, M. Šilhar, S., &Marecek, J. Extraction of Carrot (Daucus carrota L.) Carotenes Under Different Conditions. 2008;26(4):268-274.
28. Ai, S, N & Banyo, Y. Leaf Chlorophyll Concentration as an Indicator of Water Deficiency in Plants. Scientific Journal of Science. 2011;11(2):166-173.
29. Tama, B, J. Kumalaningsih, S., &Mulyadi, F, E. Study of Making Natural Dye Powder from Suji Leaves (Pleomele angustifolia NEBR.). Study of Maltodextrin and MGCO3 Concentration. Industria Journal. 2014;3(1):73-82.
30. Resita, D. Merdekawati, W. Susanto, AB., &Limantara, L. Content and Composition of Pigments of Sargassum sp. In the waters of TelukAwur, Jepara with fresh and dry treatment. Journal of Fisheries (Journal of Fisheries Scienc). 2010;12(1):11-19.
31. Wiraningtyas, A. Ruslan. Qubra, H., & Agustina, S. Stability Test and Storage of Natural Dyes Extract from Seaweed Sargassum sp. Journal of Chemistry and Applied Education. 2020;3(1):1-7.
32. Nurliasari, D &Wiraputra, D.Production of Encapsulated Chlorophyll Pigment FromKangkung Leaves (Ipomea reptanspoir.) Using Microencapsulation Technique. Industrial Agri Technology Magazine (TEGI). 2018;10(1).
33. Noer, S. Pratiwi, D, R., &Gresinta. E. Determination of Phytochemical Compound Levels (Tannins, Saponins, and Flavonoids) as Quercetin in Inggu Leaf Extract (Ruta angustifolia L.). Exact Journal. 2018;18(1):19-29.
34. Putri, C, T, K, N. Ratnawati, A, A, G, I., &Suharta, G, W. 2019. Analysis of Natural Pigments for Mango Leaves (Mangifera indicalinn) As Batik Dyes WithUv-Vis. Kappa Journal. 2019;3(2):134-141.
35. Bahri, S. Jalaluddin., &Rosnita. Manufacture of naturalfrom the bark of Jamblang(Syzygiumcumini)dyesas a basic ingredient for textile dyes. Journal of Chemical Technology Unimal. 2017;6(1):10-19.
36. Prabhu, H, K &Teli, D, M. Eco-Dyeing Using Tamarindus indica L. Seed Coat Tannin as a Natural Mordant For Textile With Antibacterial Activity. Journal of the Saudi Chemical Society. 2014;18(6):864-872.
37. Manimozhi, R &Kanakarajan, S. Natural Dye from Torenia SP Flower For Coloring Silk Yarn Using Biomordants-An Eco Friendly Approach. Journal of Chemical And Pharmacetical Research. 2017;9(11):17-26.
38. Hidjrawan, Y. Identification of Tannin Compounds in Wuluh Starfruit Leaves (Averrhoa belimbi L.). Optimization Journal. 2018;4(2):78-82.
39. Sangadji, I. Rijal, M., &Astri, Y. Anthocyanin Content in Flower Crowns of Several Ornamental Plants. Journal of Biology Science & Education. 2017;6(2):118-128.
40. Ramadani, R, F. Saisa. Ceriana, R., &Andayani, T. Utilization of Red Dragon Fruit Peel (Hylocereuspolyrhizus) as Natural Color for Blush on Cosmetics. Journal of Healthcare Technology and Medicine. 2018;4(2):165-175.
41. Handarini, K. Potential of Rosella Flower Extract (Hibiscus sabdariffa L.) As Natural Colorants and Preservatives in Snack Jelly for Children. HEURISTIC Industrial Telknik Journal. 2014;11(2):32-42.
42. Rachmawati, W. Ramdanawati, L. Development of Chlorophyll from Cassava Leaves as Natural Food Coloring. Pharmacoscript. 2020;2(2):87-97.
43. Ekawati, P. Rostiati., &Syahraeni. Application of Dragon Fruit Peel Extract as Natural Dyes in Soy Milk and Coconut Milk. ej. Agrotechbists. 2015;3(2):198-205.
44. Atma, Y. Study on the Use of Angkak as Natural Dyes in Beef Sausage Processing. Journal of Technology. 2015;7(2):76-85.
45. Dwicahyani, U. Isrul, M., &Noviyanti, N, O, W. Lipstick Formulation for Ruruhi Fruit Peel Extract (SyzygiumpolicephalumMerr) asColor.Journal of the IndonesianMandalaPharmacon. 2019;5(2):91-103.
46. Yulyuswarni. Red Dragon Fruit Peel Extract Formulation (Hylocereuspolyrhizus) As Natural Color in Lipstick Preparations. Journal of Health Analysis. 2018;7(1):673-679.
47. Supomo, Setiawan, D., &Ayusia, S. Utilization of Secang Wood Infusion (Caesalpinia sappan L.) in Hair Dye Preparation Formulas. Mulawarman Journal of Chemistry. 2014;11(2):59-63.
48. Iqbal, Z. Liaqat, L. Waheed, A., & Mahmood, K. Formulation of Natural Hair Colors From Herbs And Dry-Fruit Hulls From Pakistan. World Journal of Pharmaceutical Research.2015;5(1):1598-1602.
49. Setiawati, E &Suharyani, I. Lip gloss formulations made from Dayak onions (Eleutherinapalmifolia L. Merr) as natural cosmetic dyes. Muhammadiyah Kuningan Pharmacy Journal. 2018;3(2):30-38.
50. Bindharawati, N. Darsono, L, F., & Wijaya, S. The formulation of a blush on from Rosella flower petal extract (Hibiscus sabdariffa Linn.) As a dye in the form of a compact powder. Journal of Pharmaceutical Science And Pharmacy Practice. 2015;2(2):33-36.
51. Fitri, A, Z. Ambarwati, S, S, N., &Jubaedah, L. Utilization of thick extract of secang stem bark (Caesalpinia sappan L) as a coloring agent in blush on compact preparations. Journal of Makeup. 2020;10(1):61-71.
52. Pratimasari, D &Lindawati, Y, N. Color Optimization of TelangFlowers(Clitoriaternatea) as Natural Dyes in Paracetamol Syrup. Manuntung Scientific Journal. 2018;4(2):89-97.
53. Asra, R. Yetti, D, R. Rusdi, Audina, S & Nessa, N. Physicochemical Study of Betacyaninin Dragon Fruit Peel and Its Application as Natural Red Color for Pharmaceutical Preparations. Galenic Journal of Pharmacy. 2019;5(2):140-146.
54. Verma, S & Gupta, G. Natural Dyes and Its Applications: A Brief Review. International Journal of Research And Analytical Reviews. 2017;4(4):57-60.
55. Adriani, A &Zarwinda, I. Education for the Community on the Dangers of Dyes Through the Publication of Qualitative Analysis Results of Synthetic Dyes in Sauce. Serambi Science Journal. 2019;20(2):218-237.
56. Guerra, E. Llompart, M., & Garcia-Jares, C. Review Analysis of Dyes In Cosmetics: Challenges And Recent Development. Cosmetics. 2018;5(47):1-15.
57. Anggraini, S &Ginting, M.Lipstick Formulation from Red Dragon Fruit Juice (Hylocereuspolyrhizus) And Turmeric (Curcuma longa L.). World Journal of Pharmacy. 2017;3(1):114-122.
58. Mamoto, V, L &Citraningtyas, G, F. Analysis of Rhodamine B on Lipstick Circulating in Manado City Market. Pharmaceutical Scientific Journal. 2013;2(2):61-66.
59. Allam, V, K & Kumar, P, G. Colorants-The Cosmetic for The Pharmaceutical Dosage Forms. International Journal of Pharmacy and Pharmaceutical Sciences. 2011;3(3):13-21.
60. Kaseke, G, F, H. Extraction of food coloring from coconut roots. Journal of Health Ecology. 2016;14(2):95-99.
61. Amanda, A &Kurniaty, I. Effect of Maceration Time on the Anthocyanin Natural Dyes from Purple Eggplant Jelly Drink. Journal of Science and technology. 2017;ISSN:2407-1846.
62. Santos, F, B. Corrêa, A, M., &Chorilli, M. Sustainability, Natiral And Organic Cosmetics: Consumer, Products, Efficacy, Toxicological and Regulatory Considerations. Brazilian Journal of Pharmaceutical Sciences. 2015;51(1):17-26.
63. Rubia & Bhardwaj, A. A Review: Natural Colors. International Journal Of Engineering Sciences & Research Technology. 2016;5(7):778-781.
64. V. Hitesh, SP Lokesh, KP Ganesh, PN Yogesh, M., & S. Shweta, G. An Overview to Some Natural Coloring Agents Used in Pharmaceutical Formulations. World Journal of Pharmaceutical Research. 2014;3(3):3904-3916.

Published

2020-10-15

How to Cite

Novelia. D. A, S., & Asra, R. (2020). A Review: Natural Resources as Natural Dyes in Pharmaceutical Products. Asian Journal of Pharmaceutical Research and Development, 8(5), 82–87. https://doi.org/10.22270/ajprd.v8i5.826

Most read articles by the same author(s)

1 2 > >>