Test of Active Compound and Activity Pirdot Leaf Extract (Sauraia Vulcani Korth.) on Candida Albicans Growth in Vitro

  • Romauli Anna Teresia Marbun Faculty of Pharmacy Institut Kesehatan Medistra Lubuk Pakam

Abstract

Objective: to determine the activity of pirdot leaf extract on the growth of Candida albicans in vitro


Design: this study was a true experiment with a post-test only control group research design. The method used agar diffusion using Kirby Bauer technique. This study used 4 variations concentration namely 10%, 20%, 40%, and 80%, positive control (ketoconazole tablets), and negative control (Dimethyl Sulfoxide). The data obtained were analyzed using descriptive statistical analysis.


Interventions: the intervened variable were compound content and antifungal activity of pirdot leaf extract concentration of inhibitory effect.


Main outcome measures: the main measurement in this study was the inhibition  concentration of pirdot leaf extract on Candida albicans growth


Results:  the results showed that the inhibitory from a concentration of 10% of 8.96 mm, the highest inhibition was at 80% of 18.33 mm.


Conclusion: it could  be concluded that pirdot leaf extract has antifungal activity against Candida albicans.


Keywords: Antifungal; Candida albicans; Diffusison Method; Saurauia vulcani Korth

Keywords: Antifungal; Candida albicans; Diffusison Method; Saurauia vulcani Korth

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Author Biography

Romauli Anna Teresia Marbun, Faculty of Pharmacy Institut Kesehatan Medistra Lubuk Pakam

Faculty of Pharmacy, Institut Kesehatan Medistra Lubuk Pakam. Indonesia

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How to Cite
Marbun, R. (2020). Test of Active Compound and Activity Pirdot Leaf Extract (Sauraia Vulcani Korth.) on Candida Albicans Growth in Vitro. Asian Journal of Pharmaceutical Research and Development, 8(5), 37-40. https://doi.org/https://doi.org/10.22270/ajprd.v8i5.825