Anti-Covid-19 Phytochemicals

Authors

  • Rajendra Singh Pawar SBS University Balawala, Dehradun-248161 (Uttarakhand), India
  • Mayank Dimri SBS University Balawala, Dehradun-248161 (Uttarakhand), India
  • Alok Maithani SBS University Balawala, Dehradun-248161 (Uttarakhand), India
  • Luv Kush SBS University Balawala, Dehradun-248161 (Uttarakhand), India

DOI:

https://doi.org/10.22270/ajprd.v8i6.807

Keywords:

Phytochemical, Covid-19, IC50, Binding affinity, Structural resemblance.

Abstract

The Phytochemicals are the future phytomedicine for Covid-19 virus, therefore their antiviral affinity was differently viewed.

 

Downloads

Download data is not yet available.

Author Biographies

Rajendra Singh Pawar, SBS University Balawala, Dehradun-248161 (Uttarakhand), India

SBS University Balawala, Dehradun-248161 (Uttarakhand), India

Mayank Dimri, SBS University Balawala, Dehradun-248161 (Uttarakhand), India

SBS University Balawala, Dehradun-248161 (Uttarakhand), India

Alok Maithani, SBS University Balawala, Dehradun-248161 (Uttarakhand), India

SBS University Balawala, Dehradun-248161 (Uttarakhand), India

Luv Kush, SBS University Balawala, Dehradun-248161 (Uttarakhand), India

SBS University Balawala, Dehradun-248161 (Uttarakhand), India

References

1. Guan, W., Ni, Z, Hu, Y., Liang, W., Ou, C., He, J., …Zhong. N. (2020). Clinical characteristics of coronavirus disease 2019 in China. The New England journal of Medicine. https://doi.org/10.1056/NEJMoa2002032
2. Bosch, B. j., van der zee, r, de haan, C. A. and Rottier, P. J. (2003). The coronavirus spike protein is a class I virus fusion protein: Structural and functional characterization of the fusion core complex. Journal of Virology. 77(16), 8801-8811. https://doi.org/10.1128/jvi.77.16.8801-8811.2003
3. Zhang. L, Shen. F. M. Chen, F. and Lin, Z (2020). Origin and evolution of the 2019 novel coronavirus Clinical infectious Diseases, ciaa112. https://doi.org/10.1093/cid/ciaa112
4. Schoeman, D., and Fielding, B. C. (2019). Coronavirus envelop protein: Current knowledge. Virology Journal, 16, 69. https://doi.org/10.1186/s12985-019-1182-0
5. SARS-CoV replication. Journal of Traditional and Complementary Medicine, 1(1), 41-50. https://doi.org/10.1016/s225-4110(16)30055-4
6. Ganjhu, R. K., Mudgal, P. P., Maity, H., Dowarha, D., Devadiga, S., Nag., S., and Arunkumar, G. (2015). Herbal plants and plant preparations as remedial approach for viral diseases. Virus, 26(4), 225-236. https:// doi.org/10.1007/s13337-015-0276-6
7. Denaro, M., Smeriglio, A, Barreca, D., De Francesco, C., Occhiuto, C., Milano, G., and Trombetta, D. (2019). Antiviral activity of plants and their isolated bioactive compounds: An update. PhytotherapyResearch.https://doi.org/10.1002/ptr.6575
8. Wen C. C., Kuo, Y. H., Jan, J. T., Liang, P. H., Wang, S. Y., Liu, H. G.,.. Yang, N. S. (2007). Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. Journal of medicinal Chemistry, 50, 4087-4095. https://doi.org/10.1021/jm070295s
9. Cao, J, Forrest, J.C, and Zhang. X. (2015). A screen of the NIH clinical collection small molecule library identifies potential anti-coronavirus drugs. Antiviral Research, 114, 1-10. https://doi.org/10.1016/j.Antiviral.2014.11.010
10. Kannan, S., Shaik Syed Ali, P., Sheeza, A., and Hemalatha, K. (2020). COVID-19 (novel coronavirus 2019)- Recent trends. European Review for Medical and Pharmacological Science, 24, 2006-2011. https://doi.org/10.26355/eurrev-202002-20378
11. Li, S, Y, Chen, C., Zhang. H. Q, Guo, H. y., Wang. L…. Tan, X.(2005). Identification of natural compounds with antiviral activities against SARS-associated coronavirus. Antiviral Research, 67, 18-23. https://doi.org/10.1016/j.antiviral.2005.02.007
12. 23386 | RSC Adv., 2020, 10, 23379-23393
13. Luv Kush et.al AJPRD 8(4) 88-90 , 2020.
14. Muhammad Tahir ulQamar, Safar M. Alqahtani, Mubarak A. Alamri, Ling-Ling Chen. Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants.February 2020 Journal of Pharmaceutical Analysis 10(4).https://doi.org/10.1016/j.jpha.2020.03.009
15. K.-C. Chou, D.-Q. Wei, and W.-Z. Zhong, ̎Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS,” Biochemical and biophysical research communications, vol. 308, no.l, pp. 148-151,2003.
16. De Haan, C. A, and Rottier, P. J (2005). Molecular interactions in the assembly of coronaviruses. Advances in virus Research, 64, 165-230. https://doi.org/10.1016/S0065-3527(05)64006-7
17. Bacha, U.; Barrila, J.; Velazquez-Campoy, A.; Leavitt, S. A.; Freire, E., Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro. Biochemistry-Us 2004, 43, 4906-4912.
18. Anand, K.; Ziebuhr, J.; Wadhwani, P.; Mesters, J. R.; Hilgenfeld, R., Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 2003, 300, 1763-1767.

Published

2020-12-15

How to Cite

Pawar, R. S., Dimri, M., Maithani, A., & Kush, L. (2020). Anti-Covid-19 Phytochemicals. Asian Journal of Pharmaceutical Research and Development, 8(6), 84–88. https://doi.org/10.22270/ajprd.v8i6.807

Most read articles by the same author(s)

1 2 > >>