A Review on Self Micro Emulsifying Drug Delivery System: An Approach to Enhance the Oral Bioavailability of Poorly Water Soluble Drug

  • Mamta Patil SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.
  • Shobha Palde SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.
  • Amol Deshmukh SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

Abstract

Self-micro emulsifying drug delivery framework is the one of the methodology for improving the solvency of the hydrophobic medication. The medications which are insoluble in water can be formulated in this technique by solubilizing it in the lipid vehicle to absorb through the membrane. The lipid and surfactants are utilized to build the solvency of the drug and improve absorption. This improves the dissolution rate of the drug by expanding its solubility. A large number of the obstacles and arrangements are depicted in this article. This system picked up consideration as it likewise improves the bioavailability of the drug. This article has total survey about SMEDDS for present work and for future viewpoint too.


 

Keywords: Self-microemulsifying, surfactant, bioavailability, absorption, ternary phase diagram.

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Author Biographies

Mamta Patil, SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

Shobha Palde, SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

Amol Deshmukh, SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

SMBT College of Pharmacy, Nandi-Hills, Dhamangaon, Nashik, Maharashtra, India.

References

1. Akula S, Gurram AK, and DevireddySR. Review on:Self-Micro-Emulsifying Drug Delivery System: An Attractive Stratergy for Enhance Therapeutic Profile. International Scholarly Research Notices, 2014; 11(8): 1-4.
2. Deshmukh AS. Review on:Recent Advances in Self Emulsifying Drug Delivery System. International Journal of Pharmaceutical Science and Nanotechnology (IJPSN), 2015; 8 (1): 3-4.
3. Deshmukh AS, Mahajan VR. Review on: Advanced Delivery of Poorly Water Soluble Drug By Lipid Based Formulation as (SMEDDS). Asian Journal of Research in Biological and Pharmaceutical Science,2015; 3 (1): 15-18.
4. Deshmukh AS, Mahajan VR. Review on: Advanced Delivery of Poorly Water Soluble Drug Atrovastain By Lipid Based Formulation as (SMEDDS). Asian Journal of Pharmaceutical Research and Development,2015; 3 (2): 22-29.
5. Dokania S, Joshi AK. Review on:Self-Micro-Emulsifying Drug Delivery System (SMEDDS) – Challenges and Road Ahead. Drug Delivery Informa Healthcare,2014; 22(6): 677.
6. Gadhe LT, Kapadi SV, Bachkar B, Gandhi M Review on: Recent Patent Review on Self-Micro-Emulsifying Drug Delivery System.World Journal of Pharmaceutical Research, 2015; 4 (3): 970.

7. Gahlawat N, Verma R, Kaushik D. Review on: Recent Development in Self-Micro-Emulsifying Drug Delivery System: An Overview. Asian Journal of Pharmaceutics, 2019; 13(1):59- 60.
8. Gautam P, Shastri D. Review on: Self –Micro Emulsifiying Drug Delivery System to enhance the solubility of the hydrophobic drugs. Current Trends InBiomedical Engineering and Biosciences (JP Juniprer), 2018; 13(4): 60.
9. Gupta RN, Gupta R, Rathore GS. Review on: Enhancement of Oral Bioavailability of Lipophilic Drug Delivery System (SMEDDS). International Journal of Drug Development and Research, 2009: 1(1):13.
10. Jaiswal JJ, Solanki AJ, Yadav SK. Review on: A Review on Solid Self Micro Emulsifying Drug Delivery System: Formulation Strategies to Improve the Bioavailability of Poorly Soluble Drug. Journal of Pharmaceutical Science and Bioscientific Research (JPSBR), 2016; 6(3):241.
1. 11. Kalamkar P, Pawar K, Baddi H, Thawkar B, Yevale R, Dr. Kale M “ Self- Micro-Emulsifying Drug Delivery System (SMEDDS). International Journal of Pharmacy and Pharmaceutical Research (IJPPR).2016; 6(3): 370
2. 12. KhedekarK, Mittal S. Review on: Self -Micro-Emulsifying Drug Delivery System. International Journal Pharmaceutical Science and Research.2013; 4 (12):4497- 4498.
3. 13. Maurya SD, Arya RK, Rajpal G, Dhakar RC. Review on: Self-Micro-Emulsifying Drug Delivery Systems (SMEDDS): A Review on Physico-Chemical and Biopharmaceutical Aspect. Journal of Drug Delivery and Therapeutics, 2017; 7(3):59- 60
4. 14. Pattewar SV, Kasture S, Pande V, Sharma S. Review on: Self-Micro-Emulsifying Drug Delivery System: A Lipid Based Drug Delivery System. International Journal of Pharmaceutical Sciences and Research, 2016; 7(2): 443-448.
5. 15. Pawar SD, Gujrathi NA, Rane BR, Pawar SP. Review on: Self-Micro-Emulsifying Drug Delivery System (SMEDDS): A Promising Drug Delivery System for Enhancement of Bioavailability. Indian Journal of Drug, 2016; 4(3):6-7.
6. 16. Potphode VR, Deshmukh AS, Mahajan VR. Review on; Self-Micro-Emulsifying Drug Delivery System: Approach for Enhancement of Bioavaibility of Poorly Water Soluble Drugs. Asian J. Pharma Tech, 2016; 6(3): 63-65.
7. 17. P. Reddy UM, P. Babu R, P. Rao M, Edukoudalu V, Malikharjunarao KR. A Review on: Self-Micro Emulsifying Drug Delivery System. International Journal of Research in Pharmaceutical and Nano Sciences, 2013; 2(3):319.
8. 18. P. Tripura S, P. Mounika. Formulation and Evaluation of SMEDDS Containing Febuxostat By Employing Arachis Oil and Labrasol As Oil and Surfactant System. World Journal of Pharmaceutical Research, 2018; 7(11): 543- 545.
9. 19. Reddy S, Katyayani T, Navatha, A, Ramya G. Review on Self- Micro-Emulsifying Drug Delivery System. International Journal of Research in Pharmaceutical Sciences, (2011); 2(3):383- 386.
10. 20. Sharma VK., Koka A, Yadar J, Sharma AK., Keservani RK. Review on: Self-Micro-Emulsifying Drug Delivery System: A Strategy to Improve Oral Bioavailability. Ars Pharmaceutical, 2016; 57(3):102, 99.
11. 21. Sharma V, Singh J, Gill B, Harikumar SL. Review on: SMEDDS: A Novel Approach For Lipophilic Drugs. International Journal Pharmaceutical Sciences and Research, 2012; 3(8):2441-2444.
12. 22. Thakare P, Mogal V, Borse P, Dusane J, Kshirsagar S. Review on: Self-Micro-Emulsified Drug Delivery System. Pharmaceutical and Biological Evaluations,2016; 3 (2):146- 147.
13. 23. V.Kaushik, S. Preethi, P. Satish, Uma Shankar MS, Thakur RS. Development of Solid Micron Emulsifying Drug Delivery System. International Journal of Pharmaceutical Science and Nanotechnology (IJPSN),2013; 6 (2):2014-2015.
14. 24. Wankhade VP, Kale NS, Tapar KK. Review on: Self Micro Emulsifying Nutraceutical and Drug Delivery Systems. International Journal of Pharmaceutical Science and Nanotechnology (IJPSN),2014; 7(3): 2521-2526.
15. 25. Wu L, QiaoY, Wang L, Guo J, Wang G, He W, Yin I, ZhaoJ. Review on: A Self-Micro-Emulsifying Drug Delivery System (SMEDDS) for a Novel Meditative Compound Against Depression: A preparation and Bioavailability study in rats.American association of pharmaceutical scientists (AAPS), 2014; 16(5):1052-1054.
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How to Cite
Patil, M., Palde, S., & Deshmukh, A. ( ). A Review on Self Micro Emulsifying Drug Delivery System: An Approach to Enhance the Oral Bioavailability of Poorly Water Soluble Drug. Asian Journal of Pharmaceutical Research and Development, 8(3), 202-208. https://doi.org/https://doi.org/10.22270/ajprd.v8i3.766