A Review on Medicinal Plants of North Eastern Region with Potential Antifertility Activity
The increase in population is becoming a comprehensive problem, causing much pressure on economic, social and natural assets. Oral contraceptive agents have improved the rate of infertility but their unusual side effects limit the use. Current antifertility therapy lacks satisfactory success due to this adverse effect; hence, patients are seeking complementary and alternative medicine for anti-fertility action. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about more than 45000 plant species and among them several thousand are claimed to possess medicinal properties. Researchers conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for anti-fertility action. This review reveals that some plants and their part used having anti-fertility action, which are helpful for researcher to develop new herbal anti-fertility formulations. In the recent years, interest in drugs of plant origin has been progressively increased. The aim of this review is to highlight the work on anti-fertility of plant origin. For women who can't use modern forms of contraception due to adverse effect or other reasons, therefore herbs can offer alternatives and reducing fertility would be better than other contraceptives. This article may help investigators to identify medicinal plants responsible for anti-fertility activity.
2. Jain S, Choudhary GP, Jain DK.Medicinal plants with potential anti-fertility activity: A review. International Journal of Green Pharmacy. 2015; 9 (4):223.
3. Zade V, Wikhe M, Dabhadkar D, Dawada S, Patil U. Antifertility efficacy of Cannabis sativa leaves on female albino rats. Int J Sci Invent Today. 2013; 2(2):107-17.
4. Purohit A. Antifertility efficacy of Curcuma longa (50% E to H extract) with special referance to serum biochemistry and fertility test. Ancient science of life. 1999; 18(3-4):192.
5. Ghosh AK, Das AK, Patra KK. Studies on antifertility effect of rhizome of Curcuma longa Linn. Asian Journal of Pharmacy and Life Science. 2011; 1(4):349-53.
6. Julaeha E, Permatasari Y, Mayanti T, Diantini A. Antifertility compound from the seeds of Carica papaya. Procedia Chemistry. 2015 Jan 1; 17:66-9.
7. Nwaehujor CO, Ode JO, Ekwere MR, Udegbunam RI. Anti-fertility effects of fractions from Carica papaya (Pawpaw) Linn. methanol root extract in male Wistar rats. Arabian Journal of Chemistry. 2014; 22.
8. Airaodion AI, Ogbuagu EO, Ekenjoku JA, Okoroukwu VN, Ogbuagu U, Airaodion EO. Antifertility effect of ethanolic leaf extract of Carica papaya in male Wistar Rats. Merit Research Journal of Medicine and Medical Science. 2019; 3(9):121-9.
9. Mishra RK, Singh SK. Antispermatogenic and antifertility effects of fruits of Piper nigrum L. in mice.
10. Ghosh A, Jana K, Pakhira BP, Tripathy A, Ghosh D. Anti-fertility effect of aqueous-ethanolic (1:1) extract of the fruit of Terminalia chebula: Rising approach towards herbal contraception. Asian Pacific Journal of Reproduction. 2015; 4(3):201-7.
11. Agrawal SS, Kumar A, Gullaiya S, Dubey V, Nagar A, Tiwari P, Dhar P, Singh V. Antifertility activity of methanolic bark extract of Aegle marmelos (L.) in male wistar rats. Journal of Pharmaceutical Sciences. 2012; 20(1):94.
12. Roop JK, Dhaliwal PK, Guraya SS. Extracts of Azadirachta indica and Melia azadarach seeds inhibit folliculogenesis in albino rats. Braz J Med Biol Res 2005; 38:943-7 Nnnn
13. Ata A, Kalhari KA, Samarasekera R. Chemical constituents of Barleria prionitis and their enzyme inhibitory and free radical scavenging activities. Phytochem Lett 2009; 2:37-40.
14. Edwin S, Joshi SB, Jain DC. Antifertility activity of leaves of Plumbago zeylanica Linn. in female albino rats. The European Journal of Contraception & Reproductive Health Care. 2009 Jan 1; 14(3):233-9.
15. Daniyal M, Akram M. Antifertility activity of medicinal plants. Journal of the Chinese Medical Association. 2015 Jul 1; 78(7):382-8.
16. Bora D, Mehmud S, Das KK, Medhi H. Report on folklore medicinal plants used for female health care in Assam (India). Int. J. Herbal. Med. 2016; 4(6):4-13.
17. Dolatabad SS, Rostami FF, Khaki A. Antifertility activity of methanolic extract of Gossypium herbaceum in female rats. BALTICA. 2014; 27(1).
18. Jadhav VM, Thorat RM, Kadam VJ, Sathe NS. Hibiscus rosa sinensis Linn–‘‘Rudrapuspa’’: A Review. J Pharm Res. 2009; 2(7):1168-73.
19. Pattanayak SP, Mazumder PM. Effect of Dendrophthoe falcata (L.f.) Ettingsh on female reproductive system in Wistar rats: A focus on antifertility efficacy. Contraception 2009; 80:314-20.
20. Jain S, Choudhary GP, Jain DK. Pharmacological evaluation and antifertility activity of Jatropha gossypifolia in rats. BioMed research international. 2013; 2013.
21. Gurumani M, Balamurugan K. Evaluation of antifertility potential of ethanolic extract of whole plant of Achyranthes aspera in female albino rats. Int J Current Pharma Rev Res. 2014; 5(1):31-6.
22. Ghimire K, Banerjee J, Gupta AK, Dahal P. Phytochemical constituents and pharmacological uses of medicinal plant Achyranthes aspera: A Review. World journal of pharmaceutical research. 2015; 4(1): 470-489.
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