In Vitro Test of Antibacterial Ethanol Extract, n-Hexane Fraction and Ethyl acetate Fraction of Sungkai Leaf (Peronema cenescens) Against Salmonella typhi

  • Sitepu Nadroh Br. Department of Pharmacy, Poltekkes Kemenkes Medan, Indonesia

Abstract

Object: This study aims to look at the class of compounds and the comparison of the antibacterial activity of ethanol extract, n-hexane fraction and ethyl acetate of Sungkai leaves against Salmonella typhi.


Methods: Study included phytochemical screening and in vitro antibacterial testing of ethanol extract, n-hexane fraction and ethyl acetate of Sungkai leaves against Salmonella typhi.


Results: obtained groups of chemical compounds alkaloids, flavonoids, glycosides, anthraquinones, tannins and triterpenoids/steroids on Sungkai leaf powder. Ethanol extract of Sungkai leaves obtained resistance at a concentration of 20% by 12.7 mm, and inhibition of the ethyl acetate fraction at a concentration of 20% of 14.8 mm.


Conclusion: Ethyl acetate fraction of Sungkai leaves have antibacterial properties against S. typhi which is greater than ethanol extract and hexane fraction of leaf heal.


 

Keywords: Antibacterial, Sungkai, Peronemacenescens, S. typhi.

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Author Biography

Sitepu Nadroh Br., Department of Pharmacy, Poltekkes Kemenkes Medan, Indonesia

Department of Pharmacy, Poltekkes Kemenkes Medan, Indonesia

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How to Cite
Br., S. ( ). In Vitro Test of Antibacterial Ethanol Extract, n-Hexane Fraction and Ethyl acetate Fraction of Sungkai Leaf (Peronema cenescens) Against Salmonella typhi. Asian Journal of Pharmaceutical Research and Development, 8(3), 59-61. https://doi.org/https://doi.org/10.22270/ajprd.v8i3.757